SERF2 and PSME3

Number of citations of the paper that reports this interaction (PubMedID 16189514)
0

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		SERF2	PSME3
Description		small EDRK-rich factor 2	proteasome activator subunit 3
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytosol	Proteasome Complex Nucleus Nucleoplasm Cytoplasm Cytosol Cilium Proteasome Activator Complex Membrane Ciliary Basal Body
	Molecular Function		P53 Binding Protein Binding Identical Protein Binding Endopeptidase Activator Activity MDM2/MDM4 Family Protein Binding
	Biological Process	Protein Destabilization	Apoptotic Process Regulation Of Proteasomal Protein Catabolic Process Regulation Of G1/S Transition Of Mitotic Cell Cycle Negative Regulation Of Extrinsic Apoptotic Signaling Pathway
Pathways			Proteasome assembly
Drugs
Diseases
GWAS
Interacting Genes		18 interacting genes: BOLL CEBPA CHD3 DAB1 GC KRTAP10-3 MDFI NELFCD PSMA3 PSME3 PTPN11 QKI RBPMS RHOXF2 SP4 THAP1 UPF2 WT1	63 interacting genes: ABCF3 ADAP1 AICDA ATN1 ATP5F1B BBS2 CASP3 CASP6 CASP7 CDC25B CDC42 CEBPA CHEK2 COIL CREBBP DEPTOR DIP2A DMRT3 DTNBP1 DVL3 EAF1 EAF2 FAM90A1 FBXL12 FMR1 FOXD4L1 FXR1 FXR2 GPATCH2L HSPA5 INPP5J ITPKB KANSL1 KBTBD7 KLF2 LNX1 MDM2 MEOX2 NCOA3 NTAQ1 NUDT18 PFDN5 PICK1 PRKAB2 PRR13 RDX RNF111 RPH3AL RPS27 SERF2 SIRT1 SMURF1 SPG7 TBXA2R THAP10 TNFAIP8L1 TP53 TXN2 UBE2H UBE2I WDR25 YWHAQ ZCCHC10
Entrez ID		10169	10197
HPRD ID		05447	05500
Ensembl ID		ENSG00000140264	ENSG00000131467
Uniprot IDs		P84101	B3KQ25 P61289 V9HWJ8
PDB IDs			7YQC 7YQD
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of RNA Metabolic Process Regulation Of Macromolecule Biosynthetic Process Regulation Of RNA Metabolic Process Negative Regulation Of Metabolic Process Regulation Of Macromolecule Metabolic Process Negative Regulation Of Biosynthetic Process Negative Regulation Of Macromolecule Metabolic Process Regulation Of Gene Expression Glial Cell Differentiation Identical Protein Binding Regulation Of Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process MRNA 3'-UTR Binding Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Astrocyte Differentiation Nucleus RNA Binding Astrocyte Differentiation Macrophage Differentiation Regulation Of Primary Metabolic Process RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Cell-cell Adhesion Involved In Neuronal-glial Interactions Involved In Cerebral Cortex Radial Glia Guided Migration Calcidiol Binding Negative Regulation Of Cortisol Secretion Genitalia Development Negative Regulation Of Growth Hormone Secretion Negative Regulation Of Type I Interferon Production Negative Regulation Of Metanephric Glomerular Mesangial Cell Proliferation Internal N(7)-methylguanine-containing RNA Reader Activity Positive Regulation Of Gene Expression Sequence-specific DNA Binding Negative Regulation Of DNA-templated Transcription Cell Development Animal Organ Regeneration Response To Vitamin B2 C/EBP Complex Negative Regulation Of RNA Biosynthetic Process Inner Ear Development Cerebellum Structural Organization Developmental Process Involved In Reproduction Proteasome Complex Intestinal Epithelial Cell Migration Adrenal Cortex Formation Positive Regulation Of Metanephric Ureteric Bud Development Visceral Serous Pericardium Development Posterior Mesonephric Tubule Development Myofibroblast Contraction	Regulation Of Translation At Presynapse, Modulating Synaptic Transmission Cellular Response To Staurosporine Response To Nutrient Levels Protein Binding Protein Domain Specific Binding Nucleus Positive Regulation Of Long-term Neuronal Synaptic Plasticity Cellular Response To Nutrient Levels Macromolecule Catabolic Process Cytosol Positive Regulation Of Protein Metabolic Process Cellular Response To Alkaloid Post-translational Protein Modification Response To Xenobiotic Stimulus Neuron Projection Response To Alkaloid Positive Regulation Of Macromolecule Metabolic Process Positive Regulation Of Metabolic Process Leukocyte Apoptotic Process Response To UV Proteolysis Regulation Of Protein Metabolic Process Signal Transduction By P53 Class Mediator Mononuclear Cell Differentiation Protein-containing Complex Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Translation Regulator Activity Cellular Response To Glucose Starvation Cellular Response To Actinomycin D Positive Regulation Of Catabolic Process Proteolysis Involved In Protein Catabolic Process Ubiquitin-dependent Protein Catabolic Process Cytoplasm Developmental Process Modification-dependent Protein Catabolic Process PML Body Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Regulation Of RNA Metabolic Process Protein Destabilization Response To Actinomycin D HLH Domain Binding Regulation Of Blood Vessel Endothelial Cell Migration Regulation Of Protein Stability Leukocyte Differentiation Protein Catabolic Process Regulation Of Long-term Neuronal Synaptic Plasticity Regulation Of MiRNA-mediated Gene Silencing Disordered Domain Specific Binding Glial Cell Apoptotic Process Positive Regulation Of Macromolecule Biosynthetic Process
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