SP4 and ZBTB7A

Number of citations of the paper that reports this interaction (PMID 12004059)
24

Data Source:
HPRD (in vitro)

		SP4	ZBTB7A
Gene Name		Sp4 transcription factor	zinc finger and BTB domain containing 7A
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Cytoplasm Microtubule Cytoskeleton Intercellular Bridge	Nucleus
	Molecular Function	Sequence-specific DNA Binding RNA Polymerase II Transcription Factor Activity DNA Binding Transcription Coactivator Activity Metal Ion Binding	DNA Binding Protein Binding Histone Acetyltransferase Binding Metal Ion Binding
	Biological Process	Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter Regulation Of Heart Contraction	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated Multicellular Organismal Development Cell Differentiation Negative Regulation Of Transcription, DNA-templated
Pathways
Drugs
Diseases
GWAS		Major depressive disorder ( 20125088) Major depressive disorder (broad) ( 20038947) Multiple cancers (lung cancer, gastric cancer, and squamous cell carcinoma) ( 23103227)
Protein-Protein Interactions		14 interactors: ADAM15 ATXN7L1 CIB3 COL8A1 E2F1 FOXP2 LMO3 NKX3-1 NRF1 POU2F1 PRR20A SERF2 SP1 ZBTB7A	12 interactors: AR BCL6 HOMEZ KHDRBS1 RELA SP1 SP3 SP4 SUMO1 TP53 ZBTB48 ZMYND8
Entrez ID		6671	51341
HPRD ID		02764	10433
Ensembl ID		ENSG00000105866	ENSG00000178951
Uniprot IDs		Q02446	O95365 Q8TB76
PDB IDs			2IF5 2NN2
Enriched GO Terms of Interacting Partners?		Transcription, DNA-templated RNA Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Receptor Binding Organ Development RNA Metabolic Process Camera-type Eye Development Multicellular Organismal Development Gene Expression Eye Development Transcription From RNA Polymerase II Promoter Camera-type Eye Morphogenesis Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Tissue Development Organ Morphogenesis Eye Morphogenesis Positive Regulation Of Transcription From RNA Polymerase II Promoter Anatomical Structure Formation Involved In Morphogenesis Developmental Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription System Development Negative Regulation Of RNA Biosynthetic Process Sensory Organ Development Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Negative Regulation Of Cellular Metabolic Process Nucleobase-containing Compound Metabolic Process Negative Regulation Of Gene Expression Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Biosynthetic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Respiratory System Development Response To Hypoxia Regulation Of Gene Expression Anatomical Structure Development Negative Regulation Of Protein Binding Regulation Of Nitrogen Compound Metabolic Process Anatomical Structure Morphogenesis Positive Regulation Of Macromolecule Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Gene Expression Collagen Catabolic Process Positive Regulation Of Cellular Biosynthetic Process Cardiovascular System Development	Transcription, DNA-templated RNA Biosynthetic Process Negative Regulation Of Biosynthetic Process Transcription From RNA Polymerase II Promoter Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Nucleobase-containing Compound Metabolic Process RNA Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Gene Expression Gene Expression Regulation Of Nitrogen Compound Metabolic Process Negative Regulation Of Transcription, DNA-templated Cellular Nitrogen Compound Metabolic Process Negative Regulation Of Nucleic Acid-templated Transcription Cellular Macromolecule Biosynthetic Process Negative Regulation Of RNA Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Nitrogen Compound Metabolic Process Negative Regulation Of Gene Expression Biosynthetic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Metabolic Process Negative Regulation Of Cellular Metabolic Process Positive Regulation Of Cellular Metabolic Process Embryonic Process Involved In Female Pregnancy B Cell Differentiation Erythrocyte Differentiation Enucleate Erythrocyte Differentiation Erythrocyte Homeostasis Positive Regulation Of Histone Deacetylation Myeloid Cell Homeostasis Cellular Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Metabolic Process Megakaryocyte Differentiation Positive Regulation Of Protein Deacetylation Liver Development B Cell Activation Definitive Hemopoiesis Positive Regulation Of Cellular Biosynthetic Process Trophectodermal Cell Differentiation Protein Localization To Nucleus Gland Development Protein Import Into Nucleus, Translocation
Tagcloud ?			acquisition actionable ar block bypassed castration conversely counteracts crpc driven elucidate facilitates identifies innovative integrated leverages mechanistically notably overcomes predictive prostate pten signature srd5a1 stratification tailored trp53 xaf1 xiap
Tagcloud (Difference) ?			acquisition actionable ar block bypassed castration conversely counteracts crpc driven elucidate facilitates identifies innovative integrated leverages mechanistically notably overcomes predictive prostate pten signature srd5a1 stratification tailored trp53 xaf1 xiap
Tagcloud (Intersection) ?