BNIP3L and ROBO2

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		BNIP3L	ROBO2
Gene Name		BCL2/adenovirus E1B 19kDa interacting protein 3-like	roundabout, axon guidance receptor, homolog 2 (Drosophila)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nuclear Envelope Mitochondrion Mitochondrial Outer Membrane Endoplasmic Reticulum Integral Component Of Membrane Intrinsic Component Of Membrane	Cell Surface Integral Component Of Membrane Axolemma Extracellular Vesicular Exosome
	Molecular Function	Protein Binding Lamin Binding Identical Protein Binding Protein Homodimerization Activity Protein Heterodimerization Activity	Protein Binding Axon Guidance Receptor Activity Identical Protein Binding
	Biological Process	Viral Process Mitochondrial Protein Catabolic Process Positive Regulation Of Apoptotic Process Negative Regulation Of Apoptotic Process Defense Response To Virus Mitochondrial Outer Membrane Permeabilization	Metanephros Development Ureteric Bud Development Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Axon Guidance Central Nervous System Development Brain Development Axon Midline Choice Point Recognition Olfactory Bulb Interneuron Development Retinal Ganglion Cell Axon Guidance Cellular Response To Hormone Stimulus Positive Regulation Of Axonogenesis Negative Regulation Of Negative Chemotaxis Negative Regulation Of Synapse Assembly Apoptotic Process Involved In Luteolysis
Pathways			Axon guidance Regulation of Commissural axon pathfinding by Slit and Robo Signaling by Robo receptor
Drugs
Diseases
GWAS			Brain imaging in schizophrenia (interaction) ( 19023125) Metabolite levels (5-HIAA/ MHPG Ratio) ( 23319000)
Protein-Protein Interactions		23 interactors: BCL2 BCL2L1 BNIP3 CAMK1D CASK CLEC7A CLN8 DOK5 DUSP3 ECM1 EWSR1 FATE1 GBP2 GNB5 KLHL23 LDLRAD1 MAP1LC3A RHEB RINT1 ROBO2 SMCO4 STEAP3 TMEM11	16 interactors: BNIP3L CENPU CPE HLA-DPB1 NR1H2 NR4A1 OLFM2 PPP1R1B RDH11 ROBO1 RPS6KA5 SLIT2 SLIT3 SSRP1 TRIM13 UBQLN4
Entrez ID		665	6092
HPRD ID		07288	11895
Ensembl ID		ENSG00000104765	ENSG00000185008
Uniprot IDs		B0AZS9 B4DTN1 O60238 Q6IBV1	Q9HCK4
PDB IDs			1UEM 1UJT 2EDJ
Enriched GO Terms of Interacting Partners?		Mitochondrial Membrane Organization Mitochondrion Organization Regulation Of Mitochondrial Membrane Permeability Regulation Of Membrane Permeability Defense Response Neuron Apoptotic Process Positive Regulation Of Intrinsic Apoptotic Signaling Pathway Neuron Death Positive Regulation Of Apoptotic Signaling Pathway Apoptotic Mitochondrial Changes Response To External Stimulus Regulation Of Mitochondrion Organization Ovulation Cycle Process Negative Regulation Of Anoikis Positive Regulation Of Apoptotic Process Regulation Of Autophagy Female Gonad Development Positive Regulation Of Programmed Cell Death Ovulation Cycle Regulation Of Anoikis Development Of Primary Female Sexual Characteristics Positive Regulation Of Cell Death Regulation Of Response To DNA Damage Stimulus Response To Stress Defense Response To Protozoan Regulation Of Signal Transduction Response To Protozoan Response To Other Organism Release Of Cytochrome C From Mitochondria Mitochondrial Transport Regulation Of Intrinsic Apoptotic Signaling Pathway Response To Biotic Stimulus Regulation Of Mitotic Cell Cycle Regulation Of Intracellular Signal Transduction Negative Regulation Of Mitochondrion Organization Negative Regulation Of Autophagy Regulation Of Mitochondrial Membrane Potential Regulation Of Signaling Positive Regulation Of Signal Transduction Innate Immune Response Positive Regulation Of Intracellular Signal Transduction Intrinsic Apoptotic Signaling Pathway Cellular Response To Organic Substance Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Regulation Of Calcium Ion Transport Membrane Organization Negative Regulation Of Calcium Ion Transport Cell Communication Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Negative Regulation Of Apoptotic Process	Roundabout Signaling Pathway Negative Regulation Of Chemokine-mediated Signaling Pathway Negative Regulation Of Cytokine-mediated Signaling Pathway Negative Regulation Of Response To Cytokine Stimulus Negative Chemotaxis Cell Migration Involved In Sprouting Angiogenesis Chemorepulsion Involved In Postnatal Olfactory Bulb Interneuron Migration Regulation Of Cytokine-mediated Signaling Pathway Apoptotic Process Involved In Luteolysis Blood Vessel Endothelial Cell Migration Regulation Of Negative Chemotaxis Luteolysis Response To Cortisol Sprouting Angiogenesis Mammary Duct Terminal End Bud Growth Signal Transduction Tangential Migration From The Subventricular Zone To The Olfactory Bulb Cellular Response To Stimulus Olfactory Bulb Interneuron Development Axon Extension Involved In Axon Guidance Signaling Endothelial Cell Migration Cell Communication Chemotaxis Cerebral Cortex Tangential Migration Positive Regulation Of Cell Death Epithelial Cell Migration Epithelium Migration Olfactory Bulb Interneuron Differentiation Response To External Stimulus Axon Guidance Developmental Growth Involved In Morphogenesis Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Chemotaxis Response To Stimulus Apoptotic Process Involved In Development Ameboidal-type Cell Migration Response To Steroid Hormone Regulation Of Cellular Process Regulation Of Protein Metabolic Process Forebrain Neuron Development Substrate-dependent Cell Migration Apoptotic Process Axonogenesis Olfactory Bulb Development Axon Extension Programmed Cell Death Cell Surface Receptor Signaling Pathway Olfactory Lobe Development Cell Death
Tagcloud ?		abrogates autophagy carried connections endoplasmic er extent hct116 interest ire1 microarray nbr1 nix p62 particular perk regulates reticulum sqstm1 stages still stress subjected transcriptional transmembrane unclear unfolded upr upregulation	arhgap18 circuitry connectivity ctxn3 deeper dlpfc epistatic fgf17 forebrain glypican gpc1 gsea gwas leverages networks neuroimaging perturbed postmortem qt quantifying reorganization robo1 rsrc1 slc12a2 strengths tnik trait unanticipated visualizing
Tagcloud (Difference) ?		abrogates autophagy carried connections endoplasmic er extent hct116 interest ire1 microarray nbr1 nix p62 particular perk regulates reticulum sqstm1 stages still stress subjected transcriptional transmembrane unclear unfolded upr upregulation	arhgap18 circuitry connectivity ctxn3 deeper dlpfc epistatic fgf17 forebrain glypican gpc1 gsea gwas leverages networks neuroimaging perturbed postmortem qt quantifying reorganization robo1 rsrc1 slc12a2 strengths tnik trait unanticipated visualizing
Tagcloud (Intersection) ?