BNIP3L and KLHL23

Number of citations of the paper that reports this interaction (PubMedID 21900206)
0

Data Source:
BioGRID (two hybrid)

		BNIP3L	KLHL23
Description		BCL2 interacting protein 3 like	kelch like family member 23
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nuclear Envelope Mitochondrion Mitochondrial Envelope Mitochondrial Outer Membrane Endoplasmic Reticulum Membrane Nuclear Speck	Cytoplasm Cul3-RING Ubiquitin Ligase Complex
	Molecular Function	Protein Binding Lamin Binding Identical Protein Binding Protein Homodimerization Activity	Protein Binding Ubiquitin-like Ligase-substrate Adaptor Activity
	Biological Process	Apoptotic Process Negative Regulation Of Mitochondrial Membrane Potential Positive Regulation Of Macroautophagy Mitochondrial Protein Catabolic Process Positive Regulation Of Mitochondrial Membrane Permeability Positive Regulation Of Apoptotic Process Negative Regulation Of Apoptotic Process Regulation Of Programmed Cell Death Negative Regulation Of Programmed Cell Death Defense Response To Virus Cellular Response To Hypoxia Mitochondrial Outer Membrane Permeabilization Regulation Of Mitophagy Regulation Of Protein Targeting To Mitochondrion	Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Pathways		TP53 Regulates Transcription of Genes Involved in Cytochrome C Release
Drugs
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Cognitive decline rate in late mild cognitive impairment ( 26252872) High light scatter reticulocyte count ( 27863252 32888494) High light scatter reticulocyte percentage of red cells ( 27863252 32888494) Immature fraction of reticulocytes ( 27863252 32888494) Lymphocyte percentage of white cells ( 32888494) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular hemoglobin concentration ( 32888494) Mean corpuscular volume ( 32888494) Red blood cell count ( 32888494) Red cell distribution width ( 27863252 32888494) Schizophrenia ( 28991256 30285260)	Common carotid intima-media thickness in HIV infection ( 29206233) Obesity-related traits ( 23251661) Platelet count ( 32888494) Plateletcrit ( 32888494)
Interacting Genes		36 interacting genes: ADIPOQ BCL2 BCL2L1 BNIP3 CAMK1D CASK CLEC7A CLN8 CYB5B DOK5 DUSP3 ECM1 EWSR1 FATE1 FBXL4 GABARAPL1 GABARAPL2 GBP2 GNB5 HTR2B KLHL23 LDLRAD1 LMNA MALL MAP1LC3A NGFR RHEB RINT1 ROBO2 SMCO4 STEAP3 TMEM11 TMEM120B TMEM132D TMPRSS4 TNMD	5 interacting genes: ANXA1 ANXA7 BNIP3L CDKN1A TK1
Entrez ID		665	151230
HPRD ID		07288	11320
Ensembl ID		ENSG00000104765	ENSG00000213160
Uniprot IDs		O60238 Q6IBV1	Q8NBE8
PDB IDs
Enriched GO Terms of Interacting Partners?		Mitophagy Autophagy Of Mitochondrion Cellular Response To Nitrogen Starvation Membrane Neuron Apoptotic Process Mitochondrial Membrane Organization Phosphatidylethanolamine Binding Mitochondrial Outer Membrane Dendritic Cell Apoptotic Process Macroautophagy Ubiquitin Protein Ligase Binding Autophagy Vacuole Organization Autophagosome Assembly Response To Nutrient Levels BH3 Domain Binding Autophagosome Organization Negative Regulation Of Autophagy Regulation Of Release Of Cytochrome C From Mitochondria Response To Oxidative Stress Protein Binding Regulation Of Autophagy Positive Regulation Of Cell Maturation Negative Regulation Of Dendritic Cell Apoptotic Process Bcl-2 Family Protein Complex Positive Regulation Of Respiratory Burst Autophagosome Maturation Mitochondrion Organization Cellular Response To Nutrient Levels Identical Protein Binding Autophagosome Membrane Cellular Response To Decreased Oxygen Levels Endoplasmic Reticulum Regulation Of Mitochondrial Membrane Permeability Response To Oxygen-glucose Deprivation Regulation Of Endothelial Cell Proliferation Nuclear Lamina Regulation Of Locomotion Cellular Response To Oxygen Levels Negative Regulation Of Apoptotic Process Chemical Homeostasis Response To Stress Apoptotic Mitochondrial Changes Positive Regulation Of Monocyte Chemotactic Protein-1 Production Regulation Of Membrane Permeability Regulation Of Mitochondrial Membrane Potential Apoptotic Process Response To Decreased Oxygen Levels Negative Regulation Of Programmed Cell Death GABA Receptor Binding	Epithelial Cell Differentiation Calcium-dependent Phospholipid Binding Keratinocyte Differentiation Phosphatidylserine Binding Vesicle Membrane Calcium-dependent Protein Binding Positive Regulation Of Programmed Cell Death Epidermal Cell Differentiation PCNA-p21 Complex Negative Regulation Of Cardiac Muscle Tissue Regeneration Thymidine Kinase Activity Regulation Of G1/S Transition Of Mitotic Cell Cycle Negative Regulation Of T-helper 2 Cell Differentiation Myoblast Migration Involved In Skeletal Muscle Regeneration Positive Regulation Of Lymphocyte Proliferation Positive Regulation Of Neutrophil Apoptotic Process Positive Regulation Of Mononuclear Cell Proliferation Positive Regulation Of Leukocyte Proliferation Regulation Of Cell Cycle G1/S Phase Transition Cellular Response To Cell-matrix Adhesion DNA Synthesis Involved In Mitotic DNA Replication Thymidine Biosynthetic Process Regulation Of Neutrophil Apoptotic Process Phospholipase A2 Inhibitor Activity Positive Regulation Of T-helper 1 Cell Differentiation Neutrophil Clearance Oncogene-induced Cell Senescence Stress-induced Premature Senescence Thymidine Metabolic Process BBSome
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