BNIP3L and CAMK1D

Number of citations of the paper that reports this interaction (PubMedID 21988832)
38

Data Source:
BioGRID (two hybrid)

		BNIP3L	CAMK1D
Description		BCL2 interacting protein 3 like	calcium/calmodulin dependent protein kinase ID
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nuclear Envelope Mitochondrion Mitochondrial Envelope Mitochondrial Outer Membrane Endoplasmic Reticulum Membrane Nuclear Speck	Nucleus Cytoplasm
	Molecular Function	Protein Binding Lamin Binding Identical Protein Binding Protein Homodimerization Activity	Nucleotide Binding Catalytic Activity Protein Kinase Activity Protein Serine/threonine Kinase Activity Calcium/calmodulin-dependent Protein Kinase Activity Protein Binding Calmodulin Binding ATP Binding Kinase Activity Transferase Activity Protein Serine Kinase Activity
	Biological Process	Apoptotic Process Negative Regulation Of Mitochondrial Membrane Potential Positive Regulation Of Macroautophagy Mitochondrial Protein Catabolic Process Positive Regulation Of Mitochondrial Membrane Permeability Positive Regulation Of Apoptotic Process Negative Regulation Of Apoptotic Process Regulation Of Programmed Cell Death Negative Regulation Of Programmed Cell Death Defense Response To Virus Cellular Response To Hypoxia Mitochondrial Outer Membrane Permeabilization Regulation Of Mitophagy Regulation Of Protein Targeting To Mitochondrion	Inflammatory Response Signal Transduction Nervous System Development Regulation Of Neuron Projection Development Positive Regulation Of Neuron Projection Development Positive Regulation Of CREB Transcription Factor Activity Positive Regulation Of Apoptotic Process Negative Regulation Of Apoptotic Process Positive Regulation Of Phagocytosis Regulation Of Dendrite Development Positive Regulation Of Respiratory Burst Regulation Of Granulocyte Chemotaxis Positive Regulation Of Neutrophil Chemotaxis
Pathways		TP53 Regulates Transcription of Genes Involved in Cytochrome C Release
Drugs			N-(5-METHYL-1H-PYRAZOL-3-YL)-2-PHENYLQUINAZOLIN-4-AMINE Fostamatinib
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Cognitive decline rate in late mild cognitive impairment ( 26252872) High light scatter reticulocyte count ( 27863252 32888494) High light scatter reticulocyte percentage of red cells ( 27863252 32888494) Immature fraction of reticulocytes ( 27863252 32888494) Lymphocyte percentage of white cells ( 32888494) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular hemoglobin concentration ( 32888494) Mean corpuscular volume ( 32888494) Red blood cell count ( 32888494) Red cell distribution width ( 27863252 32888494) Schizophrenia ( 28991256 30285260)	Anorexia nervosa ( 23568457) Attention deficit hyperactivity disorder (inattention symptoms) ( 32595297) Bipolar disorder ( 31043756) Body mass index ( 28892062) Borderline personality disorder ( 28632202) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Coronary artery aneurysm in Kawasaki disease ( 27171184) Eating disorders ( 23568457) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Gut microbiota (bacterial taxa, rank normal transformation method) ( 32572223) Gut microbiota relative abundance (Faecalibacterium) ( 33208821) Headache ( 29397368) Height ( 31562340) Household income (MTAG) ( 31844048) Obesity-related traits ( 23251661) Obstructive sleep apnea (BMI adjusted) ( 33243845) QT interval (drug interaction) ( 23459443) Response to cyclophosphamide in systemic lupus erythematosus with lupus nephritis ( 26980576) Tea consumption ( 31046077) Triglyceride levels in HIV infection ( 33109212) Type 2 diabetes ( 30718926 30297969 29358691 26961502 32499647 26818947 22885922 20862305 18372903)
Interacting Genes		36 interacting genes: ADIPOQ BCL2 BCL2L1 BNIP3 CAMK1D CASK CLEC7A CLN8 CYB5B DOK5 DUSP3 ECM1 EWSR1 FATE1 FBXL4 GABARAPL1 GABARAPL2 GBP2 GNB5 HTR2B KLHL23 LDLRAD1 LMNA MALL MAP1LC3A NGFR RHEB RINT1 ROBO2 SMCO4 STEAP3 TMEM11 TMEM120B TMEM132D TMPRSS4 TNMD	13 interacting genes: APP ASAH1 BNIP3L CAMKK1 CDC25A CUL3 GMFG LRRK2 NEDD4 NEDD4L POT1 SNCA TNFSF13
Entrez ID		665	57118
HPRD ID		07288	06409
Ensembl ID		ENSG00000104765	ENSG00000183049
Uniprot IDs		O60238 Q6IBV1	Q5SQQ7 Q8IU85
PDB IDs			2JC6 6QP5 6T28 6T29 6T6F 8BFM 8BFS
Enriched GO Terms of Interacting Partners?		Mitophagy Autophagy Of Mitochondrion Cellular Response To Nitrogen Starvation Membrane Neuron Apoptotic Process Mitochondrial Membrane Organization Phosphatidylethanolamine Binding Mitochondrial Outer Membrane Dendritic Cell Apoptotic Process Macroautophagy Ubiquitin Protein Ligase Binding Autophagy Vacuole Organization Autophagosome Assembly Response To Nutrient Levels BH3 Domain Binding Autophagosome Organization Negative Regulation Of Autophagy Regulation Of Release Of Cytochrome C From Mitochondria Response To Oxidative Stress Protein Binding Regulation Of Autophagy Positive Regulation Of Cell Maturation Negative Regulation Of Dendritic Cell Apoptotic Process Bcl-2 Family Protein Complex Positive Regulation Of Respiratory Burst Autophagosome Maturation Mitochondrion Organization Cellular Response To Nutrient Levels Identical Protein Binding Autophagosome Membrane Cellular Response To Decreased Oxygen Levels Endoplasmic Reticulum Regulation Of Mitochondrial Membrane Permeability Response To Oxygen-glucose Deprivation Regulation Of Endothelial Cell Proliferation Nuclear Lamina Regulation Of Locomotion Cellular Response To Oxygen Levels Negative Regulation Of Apoptotic Process Chemical Homeostasis Response To Stress Apoptotic Mitochondrial Changes Positive Regulation Of Monocyte Chemotactic Protein-1 Production Regulation Of Membrane Permeability Regulation Of Mitochondrial Membrane Potential Apoptotic Process Response To Decreased Oxygen Levels Negative Regulation Of Programmed Cell Death GABA Receptor Binding	Regulation Of Membrane Potential Synapse Organization Positive Regulation Of Catabolic Process Regulation Of Synapse Organization Neuromuscular Junction Development Positive Regulation Of Metabolic Process Positive Regulation Of Endocytosis Regulation Of Protein Catabolic Process Negative Regulation Of Potassium Ion Export Across Plasma Membrane Protein Monoubiquitination Positive Regulation Of Macromolecule Metabolic Process Positive Regulation Of Protein Catabolic Process Endocytosis Cell Junction Organization Cellular Response To Manganese Ion Sodium Channel Inhibitor Activity Receptor Internalization Postsynapse Potassium Channel Inhibitor Activity Regulation Of Potassium Ion Export Across Plasma Membrane Regulation Of Monoatomic Cation Transmembrane Transport Positive Regulation Of Programmed Cell Death Response To Manganese Ion Negative Regulation Of Sodium Ion Transport Extracellular Exosome Regulation Of SNARE Complex Assembly Golgi-associated Vesicle Regulation Of Monoatomic Ion Transmembrane Transport Regulation Of Protein Metabolic Process Cellular Response To Catecholamine Stimulus Import Into Cell Regulation Of Endocytosis Mitochondrial Membrane Organization Response To Metal Ion Protein Metabolic Process Regulation Of Cell Activation Regulation Of Neurotransmitter Uptake Response To Catecholamine Receptor Catabolic Process Regulation Of Metabolic Process Phospholipase Binding Regulation Of Metal Ion Transport Negative Regulation Of Potassium Ion Transmembrane Transport Positive Regulation Of Mitotic Cell Cycle Positive Regulation Of Cellular Component Organization Cellular Response To Copper Ion Regulation Of Reactive Oxygen Species Metabolic Process Growth Cone Vesicle-mediated Transport Regulation Of Autophagy
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