BNIP3L and STEAP3

Number of citations of the paper that reports this interaction (PubMedID 12606722)
37

Data Source:
HPRD (in vivo, two hybrid, in vitro)

		BNIP3L	STEAP3
Description		BCL2 interacting protein 3 like	STEAP3 metalloreductase
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nuclear Envelope Mitochondrion Mitochondrial Envelope Mitochondrial Outer Membrane Endoplasmic Reticulum Membrane Nuclear Speck	Cytoplasm Endosome Multivesicular Body Plasma Membrane Endosome Membrane Membrane
	Molecular Function	Protein Binding Lamin Binding Identical Protein Binding Protein Homodimerization Activity	Protein Binding Cupric Reductase (NADH) Activity Oxidoreductase Activity Heme Binding Identical Protein Binding Metal Ion Binding Ferric-chelate Reductase (NADPH) Activity FAD Binding
	Biological Process	Apoptotic Process Negative Regulation Of Mitochondrial Membrane Potential Positive Regulation Of Macroautophagy Mitochondrial Protein Catabolic Process Positive Regulation Of Mitochondrial Membrane Permeability Positive Regulation Of Apoptotic Process Negative Regulation Of Apoptotic Process Regulation Of Programmed Cell Death Negative Regulation Of Programmed Cell Death Defense Response To Virus Cellular Response To Hypoxia Mitochondrial Outer Membrane Permeabilization Regulation Of Mitophagy Regulation Of Protein Targeting To Mitochondrion	Monoatomic Ion Transport Iron Ion Transport Apoptotic Process Protein Secretion Copper Ion Import
Pathways		TP53 Regulates Transcription of Genes Involved in Cytochrome C Release	TP53 Regulates Transcription of Genes Involved in Cytochrome C Release CDC42 GTPase cycle RHOD GTPase cycle RHOQ GTPase cycle RHOJ GTPase cycle RHOF GTPase cycle Transferrin endocytosis and recycling
Drugs
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Cognitive decline rate in late mild cognitive impairment ( 26252872) High light scatter reticulocyte count ( 27863252 32888494) High light scatter reticulocyte percentage of red cells ( 27863252 32888494) Immature fraction of reticulocytes ( 27863252 32888494) Lymphocyte percentage of white cells ( 32888494) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular hemoglobin concentration ( 32888494) Mean corpuscular volume ( 32888494) Red blood cell count ( 32888494) Red cell distribution width ( 27863252 32888494) Schizophrenia ( 28991256 30285260)	Cocaine dependence ( 23958962) Gut microbiota (bacterial taxa, rank normal transformation method) ( 32572223) Renal cell carcinoma x sex interaction ( 31231134)
Interacting Genes		36 interacting genes: ADIPOQ BCL2 BCL2L1 BNIP3 CAMK1D CASK CLEC7A CLN8 CYB5B DOK5 DUSP3 ECM1 EWSR1 FATE1 FBXL4 GABARAPL1 GABARAPL2 GBP2 GNB5 HTR2B KLHL23 LDLRAD1 LMNA MALL MAP1LC3A NGFR RHEB RINT1 ROBO2 SMCO4 STEAP3 TMEM11 TMEM120B TMEM132D TMPRSS4 TNMD	6 interacting genes: BAD BNIP3L MTDH PKMYT1 SETD7 TPT1
Entrez ID		665	55240
HPRD ID		07288	10285
Ensembl ID		ENSG00000104765	ENSG00000115107
Uniprot IDs		O60238 Q6IBV1	B8ZZX6 Q658P3
PDB IDs			2VNS 2VQ3
Enriched GO Terms of Interacting Partners?		Mitophagy Autophagy Of Mitochondrion Cellular Response To Nitrogen Starvation Membrane Neuron Apoptotic Process Mitochondrial Membrane Organization Phosphatidylethanolamine Binding Mitochondrial Outer Membrane Dendritic Cell Apoptotic Process Macroautophagy Ubiquitin Protein Ligase Binding Autophagy Vacuole Organization Autophagosome Assembly Response To Nutrient Levels BH3 Domain Binding Autophagosome Organization Negative Regulation Of Autophagy Regulation Of Release Of Cytochrome C From Mitochondria Response To Oxidative Stress Protein Binding Regulation Of Autophagy Positive Regulation Of Cell Maturation Negative Regulation Of Dendritic Cell Apoptotic Process Bcl-2 Family Protein Complex Positive Regulation Of Respiratory Burst Autophagosome Maturation Mitochondrion Organization Cellular Response To Nutrient Levels Identical Protein Binding Autophagosome Membrane Cellular Response To Decreased Oxygen Levels Endoplasmic Reticulum Regulation Of Mitochondrial Membrane Permeability Response To Oxygen-glucose Deprivation Regulation Of Endothelial Cell Proliferation Nuclear Lamina Regulation Of Locomotion Cellular Response To Oxygen Levels Negative Regulation Of Apoptotic Process Chemical Homeostasis Response To Stress Apoptotic Mitochondrial Changes Positive Regulation Of Monocyte Chemotactic Protein-1 Production Regulation Of Membrane Permeability Regulation Of Mitochondrial Membrane Potential Apoptotic Process Response To Decreased Oxygen Levels Negative Regulation Of Programmed Cell Death GABA Receptor Binding	Positive Regulation Of Autophagy Regulation Of Mitochondrial Membrane Potential Positive Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To Osmotic Stress Regulation Of Mitochondrial Membrane Permeability Apoptotic Mitochondrial Changes Negative Regulation Of Programmed Cell Death Negative Regulation Of Apoptotic Process Regulation Of Membrane Permeability Regulation Of Autophagy Negative Regulation Of Ectoderm Development Regulation Of Programmed Cell Death Regulation Of Cellular Response To Stress Regulation Of Apoptotic Process BAD-BCL-2 Complex Positive Regulation Of Catabolic Process Positive Regulation Of Type B Pancreatic Cell Development Mitochondrial Membrane Organization Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Negative Regulation Of G2/MI Transition Of Meiotic Cell Cycle Cellular Response To Oxygen Levels Regulation Of Intrinsic Apoptotic Signaling Pathway Peptidyl-lysine Dimethylation Positive Regulation Of Mitochondrial Membrane Potential Mitochondrial Outer Membrane Intercellular Canaliculus Regulation Of G2/MI Transition Of Meiotic Cell Cycle Negative Regulation Of Meiotic Cell Cycle Phase Transition Peptidyl-lysine Monomethylation Regulation Of Type B Pancreatic Cell Development Cellular Response To Nicotine Histone H3K4 Monomethyltransferase Activity Nucleolus Mitochondrial Outer Membrane Permeabilization Mitochondrion Organization Cysteine-type Endopeptidase Activator Activity Mitochondrial Protein Catabolic Process Positive Regulation Of Membrane Potential Negative Regulation Of Mitochondrial Membrane Potential Heterochromatin Organization Response To Hypoxia Regulation Of Cellular Response To Osmotic Stress Negative Regulation Of Membrane Potential Response To Decreased Oxygen Levels Regulation Of Response To Osmotic Stress Positive Regulation Of Mitochondrial Membrane Permeability Involved In Apoptotic Process Mitochondrial Envelope Response To Oxygen Levels Lamin Binding Mitochondrial Outer Membrane Permeabilization Involved In Programmed Cell Death
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?