SNAP25 and STX5

Number of citations of the paper that reports this interaction (PMID 9325254)
12

Data Source:
BioGRID (pull down)

		SNAP25	STX5
Gene Name		synaptosomal-associated protein, 25kDa	syntaxin 5
Image
Gene Ontology Annotations	Cellular Component	Cytoplasm Trans-Golgi Network Cytosol Plasma Membrane Membrane Cell Junction Growth Cone BLOC-1 Complex SNARE Complex Vesicle Presynaptic Membrane Neuron Projection Perinuclear Region Of Cytoplasm Synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I Complex	Golgi Membrane Nucleoplasm Endoplasmic Reticulum Golgi Apparatus Integral Component Of Membrane SNARE Complex Vesicle Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane
	Molecular Function	SNAP Receptor Activity Protein Binding Syntaxin-1 Binding Calcium-dependent Protein Binding	SNARE Binding SNAP Receptor Activity Protein Binding Protein N-terminus Binding
	Biological Process	Neurotransmitter Uptake Energy Reserve Metabolic Process Synaptic Transmission Neurotransmitter Secretion Pathogenesis Regulation Of Neuron Projection Development Glutamate Secretion Synaptic Vesicle Exocytosis Synaptic Vesicle Docking Synaptic Vesicle Priming Synaptic Vesicle Fusion To Presynaptic Membrane Small Molecule Metabolic Process Regulation Of Insulin Secretion Long-term Synaptic Potentiation Regulation Of Establishment Of Protein Localization	Intracellular Protein Transport ER To Golgi Vesicle-mediated Transport Vesicle Fusion Early Endosome To Golgi Transport Retrograde Transport, Endosome To Golgi Positive Regulation Of Protein Catabolic Process Vesicle Docking Vesicle Fusion With Golgi Apparatus Golgi Disassembly Regulation Of Golgi Organization
Pathways		Dopamine Neurotransmitter Release Cycle Integration of energy metabolism Toxicity of botulinum toxin type E (BoNT/E) Toxicity of botulinum toxin type A (BoNT/A) Acetylcholine Neurotransmitter Release Cycle Regulation of insulin secretion Toxicity of botulinum toxin type C (BoNT/C) Norepinephrine Neurotransmitter Release Cycle GABA synthesis, release, reuptake and degradation Glutamate Neurotransmitter Release Cycle Uptake and actions of bacterial toxins Neurotransmitter Release Cycle Neurotoxicity of clostridium toxins Serotonin Neurotransmitter Release Cycle Transmission across Chemical Synapses
Drugs		Botulinum Toxin Type A
Diseases
GWAS		Cardiac hypertrophy ( 21348951)
Protein-Protein Interactions		34 interactors: APP CCDC53 CENPF CPLX1 DNM1 GOSR1 HGS ITSN1 KCNB1 KIF5B NAPA PRKACA PRKCA PRRT2 RIMS1 SCAMP1 SNAPIN SRCIN1 STX11 STX12 STX1A STX2 STX3 STX4 STX5 STXBP6 SYT1 SYT3 SYT9 TRIM9 VAMP2 VAMP7 VAMP8 ZDHHC17	27 interactors: APLP1 ASNA1 BAG6 BET1 CCDC155 COPS6 GOSR1 GOSR2 HAP1 IMMT LNX1 LRIF1 MAGEA6 NAPA NAPB NSFL1C SCFD1 SEC22B SNAP23 SNAP25 STX4 TACC1 TP53 USO1 VAPB VCP VCPIP1
Entrez ID		6616	6811
HPRD ID		02637	04426
Ensembl ID		ENSG00000132639	ENSG00000162236
Uniprot IDs		P60880	B4DKR0 F8W8Q9 Q13190
PDB IDs		1KIL 1XTG 3RK2 3RK3 3RL0 3ZUR	3EFO
Enriched GO Terms of Interacting Partners?		Membrane Fusion Exocytosis Vesicle-mediated Transport Vesicle Fusion Synaptic Vesicle Exocytosis Synaptic Vesicle Transport Establishment Of Localization In Cell Secretion By Cell Organelle Fusion Establishment Of Vesicle Localization Vesicle Localization Regulation Of Exocytosis Secretion Neurotransmitter Secretion Cellular Localization Transport Establishment Of Organelle Localization Regulation Of Cellular Localization Synaptic Transmission Regulation Of Neurotransmitter Levels Regulation Of Secretion Organelle Localization Neurotransmitter Transport Membrane Organization Regulation Of Vesicle-mediated Transport Synaptic Vesicle Fusion To Presynaptic Membrane Protein Transport Vesicle Organization Establishment Of Protein Localization Cell-cell Signaling Vesicle Docking Intracellular Transport Membrane Docking Protein Localization Positive Regulation Of Exocytosis Calcium Ion-dependent Exocytosis Regulation Of Hormone Secretion Intracellular Protein Transport Regulation Of Cellular Component Organization Positive Regulation Of Transport Glutamate Secretion Regulation Of Synaptic Transmission Golgi Vesicle Transport Post-Golgi Vesicle-mediated Transport Regulation Of Protein Localization Positive Regulation Of Synaptic Transmission Regulation Of Insulin Secretion Cellular Protein Localization Regulation Of Peptide Hormone Secretion Acid Secretion	Membrane Fusion Golgi Vesicle Transport Membrane Organization Cellular Localization Organelle Fusion Vesicle-mediated Transport Establishment Of Protein Localization ER To Golgi Vesicle-mediated Transport Vesicle Fusion Establishment Of Localization In Cell Intracellular Transport Protein Localization Protein Transport Vesicle Organization Post-Golgi Vesicle-mediated Transport Vesicle Fusion With Golgi Apparatus Organelle Organization Synaptic Vesicle Fusion To Presynaptic Membrane Transport Cytoplasmic Transport Response To Endoplasmic Reticulum Stress SNARE Complex Disassembly Vesicle Docking Membrane Docking Organelle Localization ER-nucleus Signaling Pathway Cellular Protein Localization Endoplasmic Reticulum Organization Double-strand Break Repair Establishment Of Organelle Localization Exocytosis Protein Insertion Into ER Membrane Synaptic Vesicle Exocytosis Intra-Golgi Vesicle-mediated Transport Intracellular Protein Transport Synaptic Vesicle Priming Negative Regulation Of Macroautophagy Establishment Of Vesicle Localization Vesicle Localization Endomembrane System Organization Cellular Component Assembly Response To Stress Endoplasmic Reticulum Unfolded Protein Response Brain Development Cellular Response To Stress Cellular Response To Unfolded Protein Head Development Secretion By Cell Protein Insertion Into Membrane Neurotransmitter Secretion
Tagcloud ?		anterograde axonal axons blunt breakdown bulbous bulbs caudate circumscribed disorganized immunocytochemical immunoreactivity insult map5 mca neurofilament nf68kd nonischemic occlusion permeating precedes reminiscent roughened sequalae subcortical swellings synaptosomal territory tracts	abrasively abundant abundantly bfa bypass compartments glycosylated glycosylation golgi immature influencing insensitive interfered lipoprotein maturation modulating mutual participating partner physiology postulate reaching ribbon special syntaxin trafficking translocating vesicle vldl
Tagcloud (Difference) ?		anterograde axonal axons blunt breakdown bulbous bulbs caudate circumscribed disorganized immunocytochemical immunoreactivity insult map5 mca neurofilament nf68kd nonischemic occlusion permeating precedes reminiscent roughened sequalae subcortical swellings synaptosomal territory tracts	abrasively abundant abundantly bfa bypass compartments glycosylated glycosylation golgi immature influencing insensitive interfered lipoprotein maturation modulating mutual participating partner physiology postulate reaching ribbon special syntaxin trafficking translocating vesicle vldl
Tagcloud (Intersection) ?