SNAI1 and CTDSP2

Number of citations of the paper that reports this interaction (PMID 19004823)
17

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology)
HPRD (in vivo, in vitro)

		SNAI1	CTDSP2
Gene Name		snail family zinc finger 1	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2
Image
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm	Nucleoplasm
	Molecular Function	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Negative Regulation Of Transcription Protein Binding Kinase Binding Metal Ion Binding	Protein Binding CTD Phosphatase Activity Metal Ion Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Osteoblast Differentiation Mesoderm Formation Epithelial To Mesenchymal Transition Positive Regulation Of Epithelial To Mesenchymal Transition Negative Regulation Of Vitamin D Biosynthetic Process Cell Migration Positive Regulation Of Cell Migration Hair Follicle Morphogenesis Negative Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Positive Regulation Of Transcription, DNA-templated Palate Development Cartilage Morphogenesis Trophoblast Giant Cell Differentiation Negative Regulation Of Cell Differentiation Involved In Embryonic Placenta Development Left/right Pattern Formation Notch Signaling Involved In Heart Development Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Regulation Of Tight Junction Assembly	Negative Regulation Of Protein Phosphorylation Protein Dephosphorylation Activation Of Signaling Protein Activity Involved In Unfolded Protein Response Endoplasmic Reticulum Unfolded Protein Response Cellular Protein Metabolic Process Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle
Pathways			IRE1alpha activates chaperones XBP1(S) activates chaperone genes Unfolded Protein Response (UPR)
Drugs
Diseases
GWAS		Psoriasis ( 20953189)
Protein-Protein Interactions		19 interactors: ACTN2 CTDSP1 CTDSP2 CTDSPL FBXL14 FBXL5 GSK3B HIST1H3A HOXD4 KRT31 KRT40 KRTAP10-3 LATS2 MID2 MTUS2 NOTCH1 NOTCH2NL RCOR1 TRIM23	4 interactors: AR CDCA3 POLR2A SNAI1
Entrez ID		6615	10106
HPRD ID		05025	12281
Ensembl ID		ENSG00000124216	ENSG00000175215
Uniprot IDs		O95863	O14595
PDB IDs		2Y48	2Q5E
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Protein Phosphorylation Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Phosphorylation Protein Localization To Microtubule Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Metabolic Process Cellular Protein Modification Process Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G1/S Phase Transition Protein Localization To Cytoskeleton Cellular Protein Metabolic Process Negative Regulation Of Mitotic Cell Cycle Phase Transition Negative Regulation Of Canonical Wnt Signaling Pathway Negative Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Cell Cycle Regulation Of Hematopoietic Progenitor Cell Differentiation Negative Regulation Of Protein Metabolic Process Negative Regulation Of Neuron Differentiation Negative Regulation Of Wnt Signaling Pathway Regulation Of Mitotic Cell Cycle Phase Transition Negative Regulation Of Mitotic Cell Cycle Regulation Of Canonical Wnt Signaling Pathway Regulation Of Cell Cycle Phase Transition Protein Ubiquitination Regulation Of Protein Phosphorylation Wound Healing Positive Regulation Of Stem Cell Differentiation Protein Modification By Small Protein Conjugation Epithelial To Mesenchymal Transition Epidermis Development Venous Endothelial Cell Differentiation Notch Signaling Pathway Involved In Regulation Of Secondary Heart Field Cardioblast Proliferation Protein Metabolic Process Negative Regulation Of Neurogenesis Regulation Of Developmental Growth Response To Wounding Regulation Of Wnt Signaling Pathway Regulation Of Cellular Protein Metabolic Process Regulation Of Phosphorylation Negative Regulation Of Cell Development Negative Regulation Of Type B Pancreatic Cell Development Vasculogenesis Involved In Coronary Vascular Morphogenesis Cardiac Right Atrium Morphogenesis Mitral Valve Formation Superior Temporal Gyrus Development Negative Regulation Of Biosynthetic Process Keratinocyte Differentiation Regulation Of Nitrogen Compound Metabolic Process Cellular Metabolic Process Regulation Of Protein Metabolic Process	Negative Regulation Of Cell Differentiation Involved In Embryonic Placenta Development Negative Regulation Of Integrin Biosynthetic Process Transcription From RNA Polymerase II Promoter Transcription Initiation From RNA Polymerase II Promoter Transcription, RNA-templated Positive Regulation Of Integrin Biosynthetic Process DNA-templated Transcription, Initiation Regulation Of Integrin Biosynthetic Process Stem Cell Development Negative Regulation Of Apoptotic Signaling Pathway Negative Regulation Of Vitamin D Biosynthetic Process Positive Regulation Of Macromolecule Biosynthetic Process Stem Cell Differentiation Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Notch Signaling Involved In Heart Development Positive Regulation Of Transcription From RNA Polymerase III Promoter Regulation Of Tight Junction Assembly Negative Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Regulation Of Vitamin Metabolic Process Reproductive Structure Development Reproductive System Development Cartilage Morphogenesis Transcription, DNA-templated Trophoblast Giant Cell Differentiation Left/right Pattern Formation Regulation Of Transcription From RNA Polymerase III Promoter RNA Biosynthetic Process Negative Regulation Of Steroid Biosynthetic Process Negative Regulation Of Signal Transduction By P53 Class Mediator Negative Regulation Of Steroid Metabolic Process Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Positive Regulation Of Cellular Metabolic Process Negative Regulation Of Embryonic Development 7-methylguanosine MRNA Capping Developmental Process Involved In Reproduction PiRNA Metabolic Process Negative Regulation Of Cell Differentiation Positive Regulation Of Epithelial To Mesenchymal Transition Cell Differentiation Involved In Embryonic Placenta Development Hair Follicle Morphogenesis Positive Regulation Of RNA Splicing Androgen Receptor Signaling Pathway 7-methylguanosine RNA Capping Transcription-coupled Nucleotide-excision Repair Regulation Of Establishment Of Protein Localization To Plasma Membrane Epidermis Morphogenesis Negative Regulation Of Lipid Biosynthetic Process Regulation Of Signal Transduction By P53 Class Mediator
Tagcloud ?		aberrations apart aspect ccnd1 clinicopathological copy covered encompassed endometrial erbb1 erbb2 erbb3 erbb4 esr1 frequent infiltration insufficient myometrial pakt1 pgr pik3ca prom1 rad21 rad27 runx1 scgb2a2 snai2 top2a younger
Tagcloud (Difference) ?		aberrations apart aspect ccnd1 clinicopathological copy covered encompassed endometrial erbb1 erbb2 erbb3 erbb4 esr1 frequent infiltration insufficient myometrial pakt1 pgr pik3ca prom1 rad21 rad27 runx1 scgb2a2 snai2 top2a younger
Tagcloud (Intersection) ?