SNAI1 and TRIM23

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		SNAI1	TRIM23
Gene Name		snail family zinc finger 1	tripartite motif containing 23
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm	Golgi Membrane Nucleus Lysosomal Membrane Extracellular Vesicular Exosome
	Molecular Function	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Negative Regulation Of Transcription Protein Binding Kinase Binding Metal Ion Binding	GTPase Activity Ubiquitin-protein Transferase Activity Protein Binding GTP Binding Enzyme Activator Activity Zinc Ion Binding Ligase Activity GDP Binding Identical Protein Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Osteoblast Differentiation Mesoderm Formation Epithelial To Mesenchymal Transition Positive Regulation Of Epithelial To Mesenchymal Transition Negative Regulation Of Vitamin D Biosynthetic Process Cell Migration Positive Regulation Of Cell Migration Hair Follicle Morphogenesis Negative Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Positive Regulation Of Transcription, DNA-templated Palate Development Cartilage Morphogenesis Trophoblast Giant Cell Differentiation Negative Regulation Of Cell Differentiation Involved In Embryonic Placenta Development Left/right Pattern Formation Notch Signaling Involved In Heart Development Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Regulation Of Tight Junction Assembly	Small GTPase Mediated Signal Transduction Viral Process Protein Ubiquitination Positive Regulation Of Catalytic Activity
Pathways
Drugs
Diseases
GWAS		Psoriasis ( 20953189)
Protein-Protein Interactions		19 interactors: ACTN2 CTDSP1 CTDSP2 CTDSPL FBXL14 FBXL5 GSK3B HIST1H3A HOXD4 KRT31 KRT40 KRTAP10-3 LATS2 MID2 MTUS2 NOTCH1 NOTCH2NL RCOR1 TRIM23	137 interactors: AKTIP ANKRD36BP1 AQP1 ARFGAP1 ARHGEF3 ARNT2 ATPAF2 ATXN7 BAG1 C10orf10 C19orf57 C8orf33 CARD9 CCDC146 CCDC25 CDC20B CDR2 CFAP53 COX5B CREB5 CXCL14 CYTH1 CYTH2 DCX DMC1 DMRT3 DOCK2 EAF2 EXOC3-AS1 FAM103A1 FAM110A FAM133A FAM193B FAM208B FAM83A FAM90A1 FBF1 FHIT FLAD1 FLJ38668 FXR2 GATA2 GEM GGA2 GMCL1P1 GPANK1 GPKOW HAUS1 HOXB5 HSPB7 IQCE IQUB JOSD1 KAT5 KIFC3 KLHL42 KRT6A LGALS8 LINC00526 LINC01018 LMO2 LNX1 LOC729603 MDM2 MKRN3 MLH1 MORN4 MRPL4 MRPL45 MTFR2 NEK6 NFU1 NXT2 PHF1 PIAS2 PIK3R2 PITX1 PKP4 POLI POLL POM121 PPIL2 PPP1R18 PSMA1 RAD18 RIBC2 RNF126 RNF213 RNF32 RNF34 RSRC2 RTP5 SF1 SH2D4A SIAH1 SLC25A6 SMG9 SNAI1 SNAI2 SNRPB SORBS3 SPG21 STK19 SUMO1P1 TBC1D22B TMSB4X TNFAIP3 TRAF1 TRAIP TRIM27 TRIM29 TRIM31 TRIM32 TRIM42 TROAP TSG101 TSHZ3 TXNDC5 UBC UBE2D1 UBE2D2 UBE2D3 UBE2E1 UBE2E2 UBE2H UBE2I UBE2U UBOX5 USP2 USP20 USP21 UTP23 WDR25 ZC2HC1C ZNF250 ZNF564 ZNF581
Entrez ID		6615	373
HPRD ID		05025	03449
Ensembl ID		ENSG00000124216	ENSG00000113595
Uniprot IDs		O95863	P36406
PDB IDs		2Y48
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Protein Phosphorylation Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Phosphorylation Protein Localization To Microtubule Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Metabolic Process Cellular Protein Modification Process Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G1/S Phase Transition Protein Localization To Cytoskeleton Cellular Protein Metabolic Process Negative Regulation Of Mitotic Cell Cycle Phase Transition Negative Regulation Of Canonical Wnt Signaling Pathway Negative Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Cell Cycle Regulation Of Hematopoietic Progenitor Cell Differentiation Negative Regulation Of Protein Metabolic Process Negative Regulation Of Neuron Differentiation Negative Regulation Of Wnt Signaling Pathway Regulation Of Mitotic Cell Cycle Phase Transition Negative Regulation Of Mitotic Cell Cycle Regulation Of Canonical Wnt Signaling Pathway Regulation Of Cell Cycle Phase Transition Protein Ubiquitination Regulation Of Protein Phosphorylation Wound Healing Positive Regulation Of Stem Cell Differentiation Protein Modification By Small Protein Conjugation Epithelial To Mesenchymal Transition Epidermis Development Venous Endothelial Cell Differentiation Notch Signaling Pathway Involved In Regulation Of Secondary Heart Field Cardioblast Proliferation Protein Metabolic Process Negative Regulation Of Neurogenesis Regulation Of Developmental Growth Response To Wounding Regulation Of Wnt Signaling Pathway Regulation Of Cellular Protein Metabolic Process Regulation Of Phosphorylation Negative Regulation Of Cell Development Negative Regulation Of Type B Pancreatic Cell Development Vasculogenesis Involved In Coronary Vascular Morphogenesis Cardiac Right Atrium Morphogenesis Mitral Valve Formation Superior Temporal Gyrus Development Negative Regulation Of Biosynthetic Process Keratinocyte Differentiation Regulation Of Nitrogen Compound Metabolic Process Cellular Metabolic Process Regulation Of Protein Metabolic Process	Protein Modification By Small Protein Conjugation Protein Ubiquitination Protein Polyubiquitination Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Protein K48-linked Ubiquitination Protein Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Cellular Macromolecule Catabolic Process Negative Regulation Of Cellular Metabolic Process Cellular Metabolic Process Cellular Protein Modification Process Cellular Protein Metabolic Process Regulation Of Protein Catabolic Process Proteolysis Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Apoptotic Process Programmed Cell Death Regulation Of Metabolic Process Cellular Response To Stress Positive Regulation Of Metabolic Process Cell Death Death Gene Expression RNA Biosynthetic Process Transcription, DNA-templated Negative Regulation Of RNA Biosynthetic Process Catabolic Process Regulation Of Proteasomal Protein Catabolic Process Negative Regulation Of Gene Expression Positive Regulation Of Cellular Metabolic Process Negative Regulation Of Signal Transduction By P53 Class Mediator Negative Regulation Of Biosynthetic Process RNA Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Cellular Response To Hypoxia Protein Metabolic Process Cellular Response To Decreased Oxygen Levels Regulation Of Transcription, DNA-templated Regulation Of Proteolysis Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Cellular Response To Oxygen Levels Regulation Of Cellular Protein Metabolic Process Nucleobase-containing Compound Metabolic Process
Tagcloud ?		aberrations apart aspect ccnd1 clinicopathological copy covered encompassed endometrial erbb1 erbb2 erbb3 erbb4 esr1 frequent infiltration insufficient myometrial pakt1 pgr pik3ca prom1 rad21 rad27 runx1 scgb2a2 snai2 top2a younger	344r abrogated adaptor antiviral conjugation defense e3 ectopic embryo helicase ikkgamma innate irf3 k165 k27 lys mda5 modulator multipoints nemo polyubiquitination rig substantially tightly tlr3 tlrs toll triparite ubiquitin
Tagcloud (Difference) ?		aberrations apart aspect ccnd1 clinicopathological copy covered encompassed endometrial erbb1 erbb2 erbb3 erbb4 esr1 frequent infiltration insufficient myometrial pakt1 pgr pik3ca prom1 rad21 rad27 runx1 scgb2a2 snai2 top2a younger	344r abrogated adaptor antiviral conjugation defense e3 ectopic embryo helicase ikkgamma innate irf3 k165 k27 lys mda5 modulator multipoints nemo polyubiquitination rig substantially tightly tlr3 tlrs toll triparite ubiquitin
Tagcloud (Intersection) ?