SNAI1 and CTDSPL

Number of citations of the paper that reports this interaction (PMID 19004823)
17

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology)
HPRD (in vitro, in vivo)

		SNAI1	CTDSPL
Gene Name		snail family zinc finger 1	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like
Image
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm	Nucleus Extracellular Vesicular Exosome
	Molecular Function	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Negative Regulation Of Transcription Protein Binding Kinase Binding Metal Ion Binding	Molecular_function Phosphoprotein Phosphatase Activity Metal Ion Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Osteoblast Differentiation Mesoderm Formation Epithelial To Mesenchymal Transition Positive Regulation Of Epithelial To Mesenchymal Transition Negative Regulation Of Vitamin D Biosynthetic Process Cell Migration Positive Regulation Of Cell Migration Hair Follicle Morphogenesis Negative Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Positive Regulation Of Transcription, DNA-templated Palate Development Cartilage Morphogenesis Trophoblast Giant Cell Differentiation Negative Regulation Of Cell Differentiation Involved In Embryonic Placenta Development Left/right Pattern Formation Notch Signaling Involved In Heart Development Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Regulation Of Tight Junction Assembly	Negative Regulation Of Protein Phosphorylation Biological_process Dephosphorylation Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle
Pathways
Drugs
Diseases
GWAS		Psoriasis ( 20953189)	Prostate cancer ( 17903305)
Protein-Protein Interactions		19 interactors: ACTN2 CTDSP1 CTDSP2 CTDSPL FBXL14 FBXL5 GSK3B HIST1H3A HOXD4 KRT31 KRT40 KRTAP10-3 LATS2 MID2 MTUS2 NOTCH1 NOTCH2NL RCOR1 TRIM23	2 interactors: CDK9 SNAI1
Entrez ID		6615	10217
HPRD ID		05025	12264
Ensembl ID		ENSG00000124216	ENSG00000144677
Uniprot IDs		O95863	O15194
PDB IDs		2Y48	2HHL
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Protein Phosphorylation Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Phosphorylation Protein Localization To Microtubule Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Metabolic Process Cellular Protein Modification Process Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G1/S Phase Transition Protein Localization To Cytoskeleton Cellular Protein Metabolic Process Negative Regulation Of Mitotic Cell Cycle Phase Transition Negative Regulation Of Canonical Wnt Signaling Pathway Negative Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Cell Cycle Regulation Of Hematopoietic Progenitor Cell Differentiation Negative Regulation Of Protein Metabolic Process Negative Regulation Of Neuron Differentiation Negative Regulation Of Wnt Signaling Pathway Regulation Of Mitotic Cell Cycle Phase Transition Negative Regulation Of Mitotic Cell Cycle Regulation Of Canonical Wnt Signaling Pathway Regulation Of Cell Cycle Phase Transition Protein Ubiquitination Regulation Of Protein Phosphorylation Wound Healing Positive Regulation Of Stem Cell Differentiation Protein Modification By Small Protein Conjugation Epithelial To Mesenchymal Transition Epidermis Development Venous Endothelial Cell Differentiation Notch Signaling Pathway Involved In Regulation Of Secondary Heart Field Cardioblast Proliferation Protein Metabolic Process Negative Regulation Of Neurogenesis Regulation Of Developmental Growth Response To Wounding Regulation Of Wnt Signaling Pathway Regulation Of Cellular Protein Metabolic Process Regulation Of Phosphorylation Negative Regulation Of Cell Development Negative Regulation Of Type B Pancreatic Cell Development Vasculogenesis Involved In Coronary Vascular Morphogenesis Cardiac Right Atrium Morphogenesis Mitral Valve Formation Superior Temporal Gyrus Development Negative Regulation Of Biosynthetic Process Keratinocyte Differentiation Regulation Of Nitrogen Compound Metabolic Process Cellular Metabolic Process Regulation Of Protein Metabolic Process	Regulation Of Response To DNA Damage Stimulus Negative Regulation Of Cell Differentiation Involved In Embryonic Placenta Development Replication Fork Arrest Negative Regulation Of Vitamin D Biosynthetic Process Notch Signaling Involved In Heart Development Regulation Of Tight Junction Assembly Negative Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Regulation Of Vitamin Metabolic Process Transcription From RNA Polymerase II Promoter Cartilage Morphogenesis Trophoblast Giant Cell Differentiation Left/right Pattern Formation Negative Regulation Of Steroid Biosynthetic Process Negative Regulation Of Cell Cycle Arrest Negative Regulation Of Signal Transduction By P53 Class Mediator Negative Regulation Of Steroid Metabolic Process Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Negative Regulation Of Embryonic Development Positive Regulation Of Epithelial To Mesenchymal Transition Cell Differentiation Involved In Embryonic Placenta Development Hair Follicle Morphogenesis Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Biosynthetic Process Epidermis Morphogenesis Negative Regulation Of Lipid Biosynthetic Process Regulation Of Signal Transduction By P53 Class Mediator Positive Regulation Of Viral Transcription Negative Regulation Of DNA Replication Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Skin Morphogenesis Positive Regulation Of Stem Cell Differentiation Positive Regulation Of Cellular Biosynthetic Process Epithelial To Mesenchymal Transition Regulation Of Epithelial To Mesenchymal Transition Regulation Of Cell Junction Assembly Transcription Elongation From RNA Polymerase II Promoter Regulation Of DNA Repair Regulation Of Viral Transcription Regulation Of Steroid Biosynthetic Process Positive Regulation Of Viral Process Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Lipid Metabolic Process Regulation Of Cellular Component Organization DNA-templated Transcription, Elongation Mesoderm Formation Mesoderm Morphogenesis Negative Regulation Of Cellular Metabolic Process Hair Follicle Development
Tagcloud ?		aberrations apart aspect ccnd1 clinicopathological copy covered encompassed endometrial erbb1 erbb2 erbb3 erbb4 esr1 frequent infiltration insufficient myometrial pakt1 pgr pik3ca prom1 rad21 rad27 runx1 scgb2a2 snai2 top2a younger	adc aldh1l1 ankrd28 bhlhe40 cggbp1 ephb1 fbln2 fgd5 foxp1 gnai2 gorasp1 iqsec1 itga itga9 loc285205 loc285375 lrrc3b lrrn1 mitf nkiras1 noti rbsp3 rpl15 rpl32 thrb ttc21 ube2e2 vhl wnt7a
Tagcloud (Difference) ?		aberrations apart aspect ccnd1 clinicopathological copy covered encompassed endometrial erbb1 erbb2 erbb3 erbb4 esr1 frequent infiltration insufficient myometrial pakt1 pgr pik3ca prom1 rad21 rad27 runx1 scgb2a2 snai2 top2a younger	adc aldh1l1 ankrd28 bhlhe40 cggbp1 ephb1 fbln2 fgd5 foxp1 gnai2 gorasp1 iqsec1 itga itga9 loc285205 loc285375 lrrc3b lrrn1 mitf nkiras1 noti rbsp3 rpl15 rpl32 thrb ttc21 ube2e2 vhl wnt7a
Tagcloud (Intersection) ?