CTDSP2

Gene Name		CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2
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Gene Ontology Annotations	Cellular Component	Nucleoplasm
	Molecular Function	Protein Binding CTD Phosphatase Activity Metal Ion Binding
	Biological Process	Negative Regulation Of Protein Phosphorylation Protein Dephosphorylation Activation Of Signaling Protein Activity Involved In Unfolded Protein Response Endoplasmic Reticulum Unfolded Protein Response Cellular Protein Metabolic Process Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle
Pathways		IRE1alpha activates chaperones XBP1(S) activates chaperone genes Unfolded Protein Response (UPR)
Drugs
Diseases
GWAS
Protein-protein Interactions		4 interactors: AR CDCA3 POLR2A SNAI1
Entrez ID		10106
HPRD ID		12281
Ensembl ID		ENSG00000175215
Uniprot IDs		O14595
PDB IDs		2Q5E
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Cell Differentiation Involved In Embryonic Placenta Development Negative Regulation Of Integrin Biosynthetic Process Transcription From RNA Polymerase II Promoter Transcription Initiation From RNA Polymerase II Promoter Transcription, RNA-templated Positive Regulation Of Integrin Biosynthetic Process DNA-templated Transcription, Initiation Regulation Of Integrin Biosynthetic Process Stem Cell Development Negative Regulation Of Apoptotic Signaling Pathway Negative Regulation Of Vitamin D Biosynthetic Process Positive Regulation Of Macromolecule Biosynthetic Process Stem Cell Differentiation Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Notch Signaling Involved In Heart Development Positive Regulation Of Transcription From RNA Polymerase III Promoter Regulation Of Tight Junction Assembly Negative Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Regulation Of Vitamin Metabolic Process Reproductive Structure Development Reproductive System Development Cartilage Morphogenesis Transcription, DNA-templated Trophoblast Giant Cell Differentiation Left/right Pattern Formation Regulation Of Transcription From RNA Polymerase III Promoter RNA Biosynthetic Process Negative Regulation Of Steroid Biosynthetic Process Negative Regulation Of Signal Transduction By P53 Class Mediator Negative Regulation Of Steroid Metabolic Process Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Positive Regulation Of Cellular Metabolic Process Negative Regulation Of Embryonic Development 7-methylguanosine MRNA Capping Developmental Process Involved In Reproduction PiRNA Metabolic Process Negative Regulation Of Cell Differentiation Positive Regulation Of Epithelial To Mesenchymal Transition Cell Differentiation Involved In Embryonic Placenta Development Hair Follicle Morphogenesis Positive Regulation Of RNA Splicing Androgen Receptor Signaling Pathway 7-methylguanosine RNA Capping Transcription-coupled Nucleotide-excision Repair Regulation Of Establishment Of Protein Localization To Plasma Membrane Epidermis Morphogenesis Negative Regulation Of Lipid Biosynthetic Process Regulation Of Signal Transduction By P53 Class Mediator
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