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SMARCC2 and POLR2C
Number of citations of the paper that reports this interaction (PMID
16169070
)
531
Data Source:
HPRD
(two hybrid)
SMARCC2
POLR2C
Gene Name
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2
polymerase (RNA) II (DNA directed) polypeptide C, 33kDa
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Nuclear Chromatin
Nucleoplasm
SWI/SNF Complex
Transcriptional Repressor Complex
Protein Complex
NpBAF Complex
NBAF Complex
Nucleus
Nucleoplasm
DNA-directed RNA Polymerase II, Core Complex
Cytoplasm
Microtubule Cytoskeleton
Molecular Function
RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding
RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding
Transcription Coactivator Activity
Protein Binding
Nucleosomal DNA Binding
RNA Polymerase II Activity
DNA Binding
Protein Dimerization Activity
Biological Process
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Chromatin Organization
Nucleosome Disassembly
Chromatin Remodeling
Transcription, DNA-templated
Regulation Of Transcription From RNA Polymerase II Promoter
Regulation Of Transcription From RNA Polymerase II Promoter Involved In Forebrain Neuron Fate Commitment
ATP-dependent Chromatin Remodeling
Negative Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription, DNA-templated
MRNA Splicing, Via Spliceosome
DNA Repair
Transcription-coupled Nucleotide-excision Repair
Nucleotide-excision Repair
Transcription From RNA Polymerase II Promoter
Transcription Initiation From RNA Polymerase II Promoter
Transcription Elongation From RNA Polymerase II Promoter
7-methylguanosine MRNA Capping
RNA Splicing
Gene Expression
Viral Process
PiRNA Metabolic Process
Somatic Stem Cell Maintenance
Positive Regulation Of Viral Transcription
Pathways
Chromatin modifying enzymes
Chromatin organization
RMTs methylate histone arginines
RNA Polymerase II Promoter Escape
mRNA Splicing
Formation of HIV-1 elongation complex containing HIV-1 Tat
PIWI-interacting RNA (piRNA) biogenesis
Nucleotide Excision Repair
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
RNA Polymerase II Transcription
Abortive elongation of HIV-1 transcript in the absence of Tat
HIV Infection
Regulatory RNA pathways
Formation of the Early Elongation Complex
Tat-mediated elongation of the HIV-1 transcript
Tat-mediated HIV elongation arrest and recovery
Formation of transcription-coupled NER (TC-NER) repair complex
RNA Pol II CTD phosphorylation and interaction with CE
RNA Polymerase II Pre-transcription Events
Dual incision reaction in TC-NER
Influenza Life Cycle
HIV elongation arrest and recovery
HIV Life Cycle
HIV Transcription Initiation
Influenza Viral RNA Transcription and Replication
RNA Pol II CTD phosphorylation and interaction with CE
Transcriptional regulation of pluripotent stem cells
RNA Polymerase II HIV Promoter Escape
HIV Transcription Elongation
POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation
Transcriptional regulation by small RNAs
Processing of Capped Intron-Containing Pre-mRNA
mRNA Capping
mRNA Splicing - Minor Pathway
mRNA Splicing - Major Pathway
MicroRNA (miRNA) biogenesis
Influenza Infection
Pausing and recovery of Tat-mediated HIV elongation
Late Phase of HIV Life Cycle
Formation of RNA Pol II elongation complex
RNA Polymerase II Transcription Initiation And Promoter Clearance
Pausing and recovery of HIV elongation
Formation of HIV elongation complex in the absence of HIV Tat
Transcription-coupled NER (TC-NER)
Viral Messenger RNA Synthesis
Formation of the HIV-1 Early Elongation Complex
RNA Polymerase II Transcription Initiation
Transcription of the HIV genome
RNA Polymerase II Transcription Elongation
Drugs
Diseases
GWAS
Protein-Protein Interactions
21 interactors:
ARRB2
ATXN1
ATXN1L
BAZ1B
C11orf74
CSNK2A1
GATA1
ITCH
ITSN1
KLF1
MCPH1
NOVA1
PEX14
PHYHIP
POLR2C
RAB1B
RELB
SP1
SRGAP3
TERF1
TERF2IP
26 interactors:
ATF4
ATF7IP
C11orf58
C14orf1
CCHCR1
EEF1A1
ITCH
LRIF1
MYOG
NEDD4
NFKBIA
NUDT21
POLR2A
POLR2B
POLR2D
POLR2E
POLR2F
POLR2G
POLR2H
POLR2J
POLR2K
POLR2L
SMARCC2
STC2
TAF15
UBE2W
Entrez ID
6601
5432
HPRD ID
03437
15945
Ensembl ID
ENSG00000139613
ENSG00000102978
Uniprot IDs
F8VXC8
Q8TAQ2
P19387
Q6FGR6
PDB IDs
Enriched GO Terms of Interacting Partners
?
Regulation Of Metabolic Process
Regulation Of Nitrogen Compound Metabolic Process
Positive Regulation Of Metabolic Process
Transcription, DNA-templated
Regulation Of RNA Metabolic Process
RNA Biosynthetic Process
RNA Metabolic Process
Regulation Of Gene Expression
Negative Regulation Of Cellular Metabolic Process
Gene Expression
Regulation Of Cellular Process
Regulation Of RNA Biosynthetic Process
Cellular Macromolecule Biosynthetic Process
Macromolecule Biosynthetic Process
Nucleobase-containing Compound Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Positive Regulation Of Cellular Metabolic Process
Positive Regulation Of Macromolecule Biosynthetic Process
Cellular Nitrogen Compound Metabolic Process
Regulation Of Signal Transduction
Positive Regulation Of Cellular Biosynthetic Process
Regulation Of Transcription, DNA-templated
Regulation Of Nucleic Acid-templated Transcription
Regulation Of Chromosome Organization
Telomere Maintenance Via Telomerase
Negative Regulation Of Telomere Maintenance
Developmental Process
Nitrogen Compound Metabolic Process
Regulation Of Signaling
Myeloid Cell Differentiation
Negative Regulation Of Chromosome Organization
Regulation Of Organelle Organization
Biosynthetic Process
Regulation Of Cellular Component Organization
Anatomical Structure Development
Negative Regulation Of Binding
Erythrocyte Differentiation
System Development
Rhythmic Process
Response To Stimulus
Erythrocyte Homeostasis
Regulation Of Telomere Maintenance
Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Positive Regulation Of Gene Expression
RNA-dependent DNA Replication
Megakaryocyte Differentiation
Myeloid Cell Homeostasis
Organ Development
7-methylguanosine MRNA Capping
PiRNA Metabolic Process
7-methylguanosine RNA Capping
Transcription Elongation From RNA Polymerase II Promoter
Transcription-coupled Nucleotide-excision Repair
Positive Regulation Of Viral Transcription
DNA-templated Transcription, Elongation
Somatic Stem Cell Maintenance
Regulation Of Viral Transcription
Positive Regulation Of Viral Process
Viral Process
Nucleotide-excision Repair
Transcription Initiation From RNA Polymerase II Promoter
DNA-templated Transcription, Initiation
MRNA Splicing, Via Spliceosome
Stem Cell Maintenance
RNA Splicing, Via Transesterification Reactions
Regulation Of Viral Process
RNA Splicing
Transcription From RNA Polymerase II Promoter
Stem Cell Development
Positive Regulation Of Macromolecule Biosynthetic Process
Positive Regulation Of Gene Expression
MRNA Processing
Transcription, DNA-templated
Positive Regulation Of Cellular Biosynthetic Process
Stem Cell Differentiation
RNA Biosynthetic Process
MRNA Metabolic Process
Cellular Response To Stress
Termination Of RNA Polymerase III Transcription
Transcription Elongation From RNA Polymerase III Promoter
RNA Processing
DNA Repair
Regulation Of Type I Interferon Production
NcRNA Metabolic Process
Termination Of RNA Polymerase I Transcription
Transcription Elongation From RNA Polymerase I Promoter
Regulation Of Gene Expression
RNA Metabolic Process
Negative Regulation Of Cell Differentiation
Transcription Initiation From RNA Polymerase I Promoter
Regulation Of RNA Biosynthetic Process
DNA-templated Transcription, Termination
Regulation Of RNA Metabolic Process
Transcription From RNA Polymerase I Promoter
Positive Regulation Of Type I Interferon Production
DNA Metabolic Process
Positive Regulation Of Metabolic Process
Gene Expression
Tagcloud
?
affymetrix
arrays
c10orf18
cabp4
capn10
centb1
converted
fdr
fractioned
genechip
glycerol
hybridized
or4c6
papillary
ran
sall1
serous
spata13
splicing
st
st18
subcellular
supernatants
supraspliceosome
transcriptome
wdr78
znf263
zp2
zranb2
Tagcloud (Difference)
?
affymetrix
arrays
c10orf18
cabp4
capn10
centb1
converted
fdr
fractioned
genechip
glycerol
hybridized
or4c6
papillary
ran
sall1
serous
spata13
splicing
st
st18
subcellular
supernatants
supraspliceosome
transcriptome
wdr78
znf263
zp2
zranb2
Tagcloud (Intersection)
?