SMARCC2 and C11orf74

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		SMARCC2	C11orf74
Gene Name		SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2	chromosome 11 open reading frame 74
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nuclear Chromatin Nucleoplasm SWI/SNF Complex Transcriptional Repressor Complex Protein Complex NpBAF Complex NBAF Complex
	Molecular Function	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding Transcription Coactivator Activity Protein Binding Nucleosomal DNA Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Chromatin Organization Nucleosome Disassembly Chromatin Remodeling Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Transcription From RNA Polymerase II Promoter Involved In Forebrain Neuron Fate Commitment ATP-dependent Chromatin Remodeling Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated
Pathways		Chromatin modifying enzymes Chromatin organization RMTs methylate histone arginines
Drugs
Diseases
GWAS			Cutaneous nevi ( 21478494)
Protein-Protein Interactions		21 interactors: ARRB2 ATXN1 ATXN1L BAZ1B C11orf74 CSNK2A1 GATA1 ITCH ITSN1 KLF1 MCPH1 NOVA1 PEX14 PHYHIP POLR2C RAB1B RELB SP1 SRGAP3 TERF1 TERF2IP	3 interactors: PPP1CC SLC10A1 SMARCC2
Entrez ID		6601	119710
HPRD ID		03437	14019
Ensembl ID		ENSG00000139613	ENSG00000166352
Uniprot IDs		F8VXC8 Q8TAQ2	A8K468 Q86VG3
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Metabolic Process Transcription, DNA-templated Regulation Of RNA Metabolic Process RNA Biosynthetic Process RNA Metabolic Process Regulation Of Gene Expression Negative Regulation Of Cellular Metabolic Process Gene Expression Regulation Of Cellular Process Regulation Of RNA Biosynthetic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Regulation Of Signal Transduction Positive Regulation Of Cellular Biosynthetic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of Chromosome Organization Telomere Maintenance Via Telomerase Negative Regulation Of Telomere Maintenance Developmental Process Nitrogen Compound Metabolic Process Regulation Of Signaling Myeloid Cell Differentiation Negative Regulation Of Chromosome Organization Regulation Of Organelle Organization Biosynthetic Process Regulation Of Cellular Component Organization Anatomical Structure Development Negative Regulation Of Binding Erythrocyte Differentiation System Development Rhythmic Process Response To Stimulus Erythrocyte Homeostasis Regulation Of Telomere Maintenance Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Positive Regulation Of Gene Expression RNA-dependent DNA Replication Megakaryocyte Differentiation Myeloid Cell Homeostasis Organ Development	Regulation Of Transcription From RNA Polymerase II Promoter Involved In Forebrain Neuron Fate Commitment Nucleosome Disassembly Forebrain Neuron Fate Commitment Triglyceride Catabolic Process Regulation Of Transcription Involved In Cell Fate Commitment Entrainment Of Circadian Clock By Photoperiod Photoperiodism Entrainment Of Circadian Clock Acylglycerol Catabolic Process
Tagcloud ?		affymetrix arrays c10orf18 cabp4 capn10 centb1 converted fdr fractioned genechip glycerol hybridized or4c6 papillary ran sall1 serous spata13 splicing st st18 subcellular supernatants supraspliceosome transcriptome wdr78 znf263 zp2 zranb2
Tagcloud (Difference) ?		affymetrix arrays c10orf18 cabp4 capn10 centb1 converted fdr fractioned genechip glycerol hybridized or4c6 papillary ran sall1 serous spata13 splicing st st18 subcellular supernatants supraspliceosome transcriptome wdr78 znf263 zp2 zranb2
Tagcloud (Intersection) ?