SMARCC2 and NOVA1

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
HPRD (two hybrid)

		SMARCC2	NOVA1
Gene Name		SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2	neuro-oncological ventral antigen 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nuclear Chromatin Nucleoplasm SWI/SNF Complex Transcriptional Repressor Complex Protein Complex NpBAF Complex NBAF Complex	Nucleus Nucleolus Intracellular Membrane-bounded Organelle
	Molecular Function	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding Transcription Coactivator Activity Protein Binding Nucleosomal DNA Binding	RNA Binding MRNA Binding Poly(A) RNA Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Chromatin Organization Nucleosome Disassembly Chromatin Remodeling Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Transcription From RNA Polymerase II Promoter Involved In Forebrain Neuron Fate Commitment ATP-dependent Chromatin Remodeling Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated	MRNA Splicing, Via Spliceosome RNA Processing Synaptic Transmission Locomotory Behavior RNA Splicing Regulation Of RNA Metabolic Process
Pathways		Chromatin modifying enzymes Chromatin organization RMTs methylate histone arginines
Drugs
Diseases
GWAS
Protein-Protein Interactions		21 interactors: ARRB2 ATXN1 ATXN1L BAZ1B C11orf74 CSNK2A1 GATA1 ITCH ITSN1 KLF1 MCPH1 NOVA1 PEX14 PHYHIP POLR2C RAB1B RELB SP1 SRGAP3 TERF1 TERF2IP	5 interactors: APP PCBP1 RPP14 SMARCC2 SRPK1
Entrez ID		6601	4857
HPRD ID		03437	03693
Ensembl ID		ENSG00000139613	ENSG00000139910
Uniprot IDs		F8VXC8 Q8TAQ2	B7Z770 P51513
PDB IDs			1DT4 2ANN 2ANR
Enriched GO Terms of Interacting Partners?		Regulation Of Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Metabolic Process Transcription, DNA-templated Regulation Of RNA Metabolic Process RNA Biosynthetic Process RNA Metabolic Process Regulation Of Gene Expression Negative Regulation Of Cellular Metabolic Process Gene Expression Regulation Of Cellular Process Regulation Of RNA Biosynthetic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Regulation Of Signal Transduction Positive Regulation Of Cellular Biosynthetic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of Chromosome Organization Telomere Maintenance Via Telomerase Negative Regulation Of Telomere Maintenance Developmental Process Nitrogen Compound Metabolic Process Regulation Of Signaling Myeloid Cell Differentiation Negative Regulation Of Chromosome Organization Regulation Of Organelle Organization Biosynthetic Process Regulation Of Cellular Component Organization Anatomical Structure Development Negative Regulation Of Binding Erythrocyte Differentiation System Development Rhythmic Process Response To Stimulus Erythrocyte Homeostasis Regulation Of Telomere Maintenance Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Positive Regulation Of Gene Expression RNA-dependent DNA Replication Megakaryocyte Differentiation Myeloid Cell Homeostasis Organ Development	RNA Metabolic Process MRNA Processing MRNA Metabolic Process RNA Processing Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Synaptic Growth At Neuromuscular Junction Cellular Nitrogen Compound Metabolic Process Collateral Sprouting In Absence Of Injury Nitrogen Compound Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Involved In Forebrain Neuron Fate Commitment Collateral Sprouting Axon Midline Choice Point Recognition Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Axon Choice Point Recognition Neuron Remodeling Sperm Chromatin Condensation Gene Expression RNA Splicing Nucleosome Disassembly Forebrain Development Forebrain Neuron Fate Commitment Cellular Copper Ion Homeostasis Positive Regulation Of Viral Genome Replication Regulation Of Transcription Involved In Cell Fate Commitment Copper Ion Homeostasis Suckling Behavior Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle
Tagcloud ?		affymetrix arrays c10orf18 cabp4 capn10 centb1 converted fdr fractioned genechip glycerol hybridized or4c6 papillary ran sall1 serous spata13 splicing st st18 subcellular supernatants supraspliceosome transcriptome wdr78 znf263 zp2 zranb2	181b 5p astrocytoma astrocytomas changing downregulated downregulating ectopic invasion inversely micrornas mir mirna mirnas modulate neuro neuroepithelial noncoding numerous oncogenes oncological overexpressed restoring reversed rnas suppressors untranslated utr ventral
Tagcloud (Difference) ?		affymetrix arrays c10orf18 cabp4 capn10 centb1 converted fdr fractioned genechip glycerol hybridized or4c6 papillary ran sall1 serous spata13 splicing st st18 subcellular supernatants supraspliceosome transcriptome wdr78 znf263 zp2 zranb2	181b 5p astrocytoma astrocytomas changing downregulated downregulating ectopic invasion inversely micrornas mir mirna mirnas modulate neuro neuroepithelial noncoding numerous oncogenes oncological overexpressed restoring reversed rnas suppressors untranslated utr ventral
Tagcloud (Intersection) ?