BRD9 and MAP1LC3A

Number of citations of the paper that reports this interaction (PubMedID 37219487)
66

Data Source:
BioGRID (unspecified method)

		BRD9	MAP1LC3A
Description		bromodomain containing 9	microtubule associated protein 1 light chain 3 alpha
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GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm SWI/SNF Complex GBAF Complex	Autophagosome Membrane Cytoplasm Late Endosome Autophagosome Cytosol Cytoskeleton Microtubule Endomembrane System Membrane Organelle Membrane Cytoplasmic Vesicle Autolysosome Synapse Glutamatergic Synapse
	Molecular Function	Nucleic Acid Binding Protein Binding Histone Reader Activity	Protein Binding Phospholipid Binding Microtubule Binding Phosphatidylethanolamine Binding Ubiquitin Protein Ligase Binding
	Biological Process	Chromatin Organization Chromatin Remodeling Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Cell Population Proliferation Negative Regulation Of Cell Differentiation Positive Regulation Of Stem Cell Population Maintenance	Autophagosome Assembly Autophagy Of Mitochondrion Mitophagy Autophagy Cellular Response To Nitrogen Starvation JNK Cascade Cellular Response To Starvation Response To Iron(II) Ion Response To Lead Ion Macroautophagy Response To Nutrient Levels Cellular Response To Amino Acid Starvation P38MAPK Cascade SMAD Protein Signal Transduction Cellular Response To Hydrogen Peroxide Cellular Response To Copper Ion Cellular Response To Oxygen-glucose Deprivation Autophagosome Maturation
Pathways		Formation of the non-canonical BAF (ncBAF) complex	Macroautophagy PINK1-PRKN Mediated Mitophagy Receptor Mediated Mitophagy
Drugs
Diseases
GWAS		Pancreatic cancer ( 25086665)	Alanine aminotransferase levels ( 33547301) Bipolar disorder ( 31043756) Colorectal cancer or advanced adenoma ( 30510241) Fish- and plant-related diet ( 32066663) Hip circumference adjusted for BMI ( 34021172) Oily fish consumption ( 32066663) Pork consumption ( 32066663)
Interacting Genes		7 interacting genes: ATRX BRD4 CATIP GABARAPL1 GABARAPL2 MAP1LC3A MAP1LC3B	100 interacting genes: ABTB3 AKAP13 AMBRA1 ANK2 ANK3 ANKRD62 AP5B1 APOBR APP APPL1 ARHGAP6 ATF7IP2 ATG13 ATG2A ATG4B ATG7 ATXN3 BCL9 BNIP3L BRD9 CAMSAP1 CARS2 CCPG1 CDC37 CSAG1 DPPA4 DVL2 EPHA7 FUNDC1 GPSM1 HTATSF1 IRGQ IRS4 KIF15 KXD1 LINC00696 LMNB1 MAP1A MAP1S MAVS MDM2 MEFV MREG MRTFA MTX1 MYBPC1 NBR1 NCOR1 NEDD4 NEDD4L NEK9 NEURL4 OPRM1 OPTN PCNT PHB1 PIAS4 PRPF40A RABGAP1 RABGAP1L RASAL3 RDH12 RELB RESF1 RETREG3 RIC1 RTKN RTN3 SEC62 SLA2 SP1 SP3 SRPK1 STBD1 STK10 TBC1D1 TBC1D10A TBC1D10B TBC1D16 TBC1D17 TBC1D2 TBC1D25 TBC1D2B TBC1D5 TBC1D7 TBC1D9 TBC1D9B TMEM132C TNIP1 TP53INP1 TP53INP2 TRIM21 TRIM25 TRIM32 TTN TUBA4A VPS9D1 ZBTB48 ZKSCAN4 ZNF304
Entrez ID		65980	84557
HPRD ID		12532	03144
Ensembl ID		ENSG00000028310	ENSG00000101460
Uniprot IDs		B4DXI2 Q9H8M2	Q9H492
PDB IDs		3HME 4NQN 4UIT 4UIU 4UIV 4UIW 4XY8 4YY4 4YY6 4YYD 4YYG 4YYH 4YYI 4YYJ 4YYK 4Z6H 4Z6I 5E9V 5EU1 5F1H 5F1L 5F25 5F2P 5I40 5I7X 5I7Y 5IGM 5IGN 5JI8 5MKY 5TWX 6BQA 6HM0 6UZF 6V0S 6V0X 6V14 6V1B 6Y7H 6Y7I 6Y7J 6Y7K 6Y7L 6YQR 6YQS 6YQW 8A7I 8AHC	3ECI 3WAL 3WAN 4ZDV 5CX3 5DPR 6TBE 7R9W 7R9Z 7RA0 8T2L 8T35 8T36 8T4T
Enriched GO Terms of Interacting Partners?		Cellular Response To Nitrogen Starvation Phosphatidylethanolamine Binding Autophagosome Maturation Autophagosome Membrane Mitophagy Autophagy Of Mitochondrion Autophagosome Autophagosome Assembly Autophagosome Organization Phospholipid Binding Protein-containing Complex Disassembly Macroautophagy Vacuole Organization Cellular Response To Starvation Response To Starvation Cellular Response To Nutrient Levels Protein-containing Complex Organization Autophagy Ubiquitin Protein Ligase Binding Cellular Response To Stress GABA Receptor Binding Response To Nutrient Levels Cellular Component Assembly Organelle Organization Organelle Assembly Microtubule Binding Beta-tubulin Binding Organelle Membrane Cytoplasmic Vesicle Response To Stress Microtubule Histone H4K8ac Reader Activity Negative Regulation Of Maintenance Of Mitotic Sister Chromatid Cohesion, Telomeric Post-embryonic Forelimb Morphogenesis Chromosome, Subtelomeric Region Histone H3K9ac Reader Activity Histone H4K5ac Reader Activity Histone H4K12ac Reader Activity Negative Regulation Of DNA Damage Checkpoint Histone H3K27ac Reader Activity Cytoskeleton P-TEFb Complex Binding Histone H4 Reader Activity Cellular Response To Oxygen-glucose Deprivation Negative Regulation Of Sister Chromatid Cohesion Histone Binding Histone H4K16ac Reader Activity DNA Translocase Activity Chromo Shadow Domain Binding Positive Regulation Of Nuclear Cell Cycle DNA Replication	Autophagosome GTPase Activator Activity Regulation Of Cilium Assembly Autophagy Macroautophagy Positive Regulation Of Catabolic Process Positive Regulation Of Autophagy Regulation Of Organelle Assembly Autophagosome Assembly Regulation Of Cell Projection Organization Autophagosome Organization Regulation Of Cell Projection Assembly Cytoplasmic Vesicle Regulation Of Autophagy Regulation Of Plasma Membrane Bounded Cell Projection Organization Autophagy Of Mitochondrion Organelle Organization Cytosol Vacuole Organization Mitophagy Positive Regulation Of Macroautophagy Regulation Of Macroautophagy Regulation Of Cellular Component Organization Piecemeal Microautophagy Of The Nucleus Regulation Of Organelle Organization Microautophagy Nucleophagy Positive Regulation Of Metabolic Process Substrate Localization To Autophagosome M Band Cytoskeleton Organization Phagophore Assembly Site Vesicle-mediated Transport Transcription Repressor Complex Intracellular Protein Localization Regulation Of Metabolic Process Regulation Of Protein Catabolic Process Microtubule Associated Complex Regulation Of Protein Localization Negative Regulation Of Viral Process Catabolic Process Protein Kinase Regulator Activity Suppression Of Viral Release By Host Regulation Of Viral Process Regulation Of GTPase Activity Cytoplasm Ubiquitin Protein Ligase Activity Positive Regulation Of Protein Catabolic Process Cytoskeletal Anchor Activity Protein-macromolecule Adaptor Activity
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