RAPH1 and VASP

Number of citations of the paper that reports this interaction (PMID 15469845)
78

Data Source:
BioGRID (pull down)

		RAPH1	VASP
Gene Name		Ras association (RalGDS/AF-6) and pleckstrin homology domains 1	vasodilator-stimulated phosphoprotein
Image
Gene Ontology Annotations	Cellular Component	Cytoplasm Cytoskeleton Plasma Membrane Lamellipodium Filopodium	Cytoplasm Cytosol Plasma Membrane Tight Junction Focal Adhesion Actin Cytoskeleton Lamellipodium Membrane Filopodium Membrane Extracellular Vesicular Exosome
	Molecular Function	Protein Binding	Actin Binding Protein Binding Profilin Binding SH3 Domain Binding
	Biological Process	Cell-matrix Adhesion Signal Transduction Axon Extension	Neural Tube Closure Axon Guidance Actin Polymerization Or Depolymerization Positive Regulation Of Actin Filament Polymerization Cell Junction Assembly T Cell Receptor Signaling Pathway Protein Homotetramerization
Pathways			Cell junction organization TCR signaling Generation of second messenger molecules Axon guidance Signaling by Robo receptor Cell-extracellular matrix interactions Adaptive Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions		3 interactors: DNMBP SIAH1 VASP	36 interactors: ABI1 ABI2 ABI3 ACTA1 ACTG1 APBB1 APBB1IP DMRTB1 DNMBP ERMAP FAT1 FGFR1OP FYB GSN LPP NOL3 NR4A1 PFN1 PFN2 PLSCR1 PRKACA PRKG1 PRPF40A RAPH1 SAT1 SCGB2A2 SPTA1 TES TRIM9 VCL WAS WASL WWP2 XIRP1 XPO6 ZYX
Entrez ID		65059	7408
HPRD ID		12356	03415
Ensembl ID		ENSG00000173166	ENSG00000125753
Uniprot IDs		C9K0J5 Q70E73	P50552
PDB IDs		4GMV 4GN1	1EGX 1JNG 1USD 1USE 2PAV 2PBD 3CHW
Enriched GO Terms of Interacting Partners?		Axon Guidance Axonogenesis Axon Development Cell Morphogenesis Involved In Neuron Differentiation Chemotaxis Neuron Projection Morphogenesis Cell Morphogenesis Involved In Differentiation Protein Destabilization Neuron Projection Development Cell Projection Morphogenesis Cell Part Morphogenesis	Actin Cytoskeleton Organization Actin Filament-based Process Cytoskeleton Organization Actin Filament Organization Movement Of Cell Or Subcellular Component Response To Wounding Organelle Organization Positive Regulation Of Arp2/3 Complex-mediated Actin Nucleation Actin Polymerization Or Depolymerization Blood Coagulation Positive Regulation Of Actin Nucleation Wound Healing Hemostasis Platelet Activation Positive Regulation Of Cytoskeleton Organization Anatomical Structure Morphogenesis Regulation Of Actin Cytoskeleton Organization Cell Development Locomotion Negative Regulation Of Protein Complex Assembly Regulation Of Body Fluid Levels Regulation Of Actin Filament-based Process Negative Regulation Of Actin Filament Polymerization Regulation Of Arp2/3 Complex-mediated Actin Nucleation Cell Projection Organization Regulation Of Actin Nucleation Regulation Of Cytoskeleton Organization Negative Regulation Of Protein Polymerization Regulation Of Cellular Component Organization Regulation Of Cellular Process Positive Regulation Of ATPase Activity Immune Response-regulating Cell Surface Receptor Signaling Pathway Neuron Projection Development Actomyosin Structure Organization Cell Projection Morphogenesis Positive Regulation Of Organelle Organization Cell Part Morphogenesis Regulation Of ATPase Activity Positive Regulation Of Immune System Process Regulation Of Organelle Organization Anatomical Structure Development Fc Receptor Signaling Pathway Cell Activation Immune Response-regulating Signaling Pathway Immune Response-activating Cell Surface Receptor Signaling Pathway Neuron Development Regulation Of Immune System Process Regulation Of Catalytic Activity Positive Regulation Of Cellular Component Biogenesis Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis
Tagcloud ?		away cdc42 colocalize cores cortactin degrade ecm egfp gelsolin holes invade invadopodia invadopodial lamellipodial lamellipodin localizes metalloproteinases periphery podosome podosomes potentiates prel1 protrusions punctae redistribution reorganizes supervillin sv tks5	abm acta cardinal colocalize concentrates concentrating factories fppppx gppppp immunolocalization listeria microinjection motile motility perinuclear phosphoprotein profilin rear redistributed rocket shigella tails underscore vaccinia vasodilator vinculin virions xppppp zyxin
Tagcloud (Difference) ?		away cdc42 cores cortactin degrade ecm egfp gelsolin holes invade invadopodia invadopodial lamellipodial lamellipodin localizes metalloproteinases periphery podosome podosomes potentiates prel1 protrusions punctae redistribution reorganizes supervillin sv tks5	abm acta cardinal concentrates concentrating factories fppppx gppppp immunolocalization listeria microinjection motile motility perinuclear phosphoprotein profilin rear redistributed rocket shigella tails underscore vaccinia vasodilator vinculin virions xppppp zyxin
Tagcloud (Intersection) ?		colocalize