SKP2 and RB1

  • Number of citations of the paper that reports this interaction (PMID 15469821)
  • 34
  • Data Source:
  • HPRD (in vitro, in vivo)

SKP2

RB1

Gene Name S-phase kinase-associated protein 2, E3 ubiquitin protein ligase retinoblastoma 1
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 54 interactors: AKT1 BTG1 BTG2 CCNA2 CCNE1 CCNT1 CDC14B CDC34 CDH1 CDK2 CDK9 CDKN1A CDKN1B CDKN1C CDT1 CEBPA CHKA CKS1B CKS1BP7 CUL1 CUL4A DDB1 DUSP1 E2F1 ELF4 ESR1 FZR1 GPS1 KPNA1 KPNA6 MYB MYBL2 MYC NLK ORC1 PFDN1 PIM1 PSMD9 RAG2 RB1 RBL2 RND3 SIRT4 SIRT6 SKP1 SMAD4 TAL1 TCF3 TRIM21 UBB VHL WEE1 YWHAB YY1 167 interactors: AATF ABL1 AHR AR ARID3B ATF2 BAG1 BDP1 BNC2 BRCA1 BRF1 CASP10 CASP2 CASP3 CASP6 CASP7 CASP8 CASP9 CBX1 CBX4 CCNA1 CCNA2 CCNB1 CCNC CCND1 CCND2 CCND3 CCNE1 CCNT2 CDC27 CDK1 CDK14 CDK2 CDK3 CDK4 CDK5 CDK6 CDK9 CDKN1A CDKN1C CEBPA CEBPB CEBPD CEBPE CHEK1 CREG1 CTBP1 CUX1 DGKZ DNMT1 DNMT3A DYRK1A E2F1 E2F2 E2F3 E2F4 E4F1 EID1 ELF1 ENC1 EP300 FOS FRK GNB2L1 GTF3C2 HBP1 HDAC1 HDAC3 HIF1A HMGA2 HMGB1 HSPA8 ID2 INS IRF3 JUN KAT2B KAT5 KDM4A KDM5A KDM5B L3MBTL1 LIN54 LIN9 LMNA MAPK1 MAPK9 MCM7 MDM2 MDM4 MNAT1 MNDA MORF4L1 MORF4L2 MRPS18B MYC MYOD1 NCOA6 NDC80 NEFM PA2G4 PAX2 PAX5 PAX6 PELP1 PHB PIK3R1 PIK3R3 PLA2G12A PML POLA1 PPARG PPIA PPP1CA PPP1CB PPP1CC PRDM2 PRKCB PRKRA PRMT2 PSMD10 PURA RAF1 RBAK RBBP4 RBBP5 RBBP7 RBBP8 RBBP9 RING1 RINT1 RNF40 RUNX2 SERPINB2 SKP2 SMARCA4 SMARCB1 SMYD2 SNAPC1 SNAPC3 SNW1 SP1 SP3 SPI1 SPIB STAT3 SUMO1 SUMO2 SUV39H1 SUV420H2 TAF1 TBP TFAP2A TGM2 THOC1 TMPO TOP2A TRAP1 TRIM27 TRIP11 UBE2I UBTF UHRF2 USP4 USP7 VDR ZBTB16
Entrez ID 6502 5925
HPRD ID 03256 01574
Ensembl ID ENSG00000145604 ENSG00000139687
Uniprot IDs Q13309 P06400
PDB IDs 1FQV 1FS1 1FS2 1LDK 2ASS 2AST 1AD6 1GH6 1GUX 1H25 1N4M 1O9K 1PJM 2AZE 2QDJ 2R7G 3N5U 3POM 4ELJ 4ELL
Enriched GO Terms of Interacting Partners?
Tagcloud ?
antisense  box  cdc53  cdk2  cip1  complex  cul  cullin  deregulation  e3  g1  hallmark  kip1  ligase  lived  member  oligodeoxynucleotides  oligonucleotides  p19  p21  p27  p45  proteolysis  raises  scf  skp1  transformed  ubiquitin  waf1 
13q14  16q22  18q21  1p35  22p  22q  3p22  5q21  8p  9p21  apc  cent  crc  crcs  dcc  dukes  existed  frequencies  heterozygosity  loh  microsatellite  pairwise  q14  q22  rer  sporadic  ucacrc  ucacrcs  ulcerative 
Tagcloud (Difference) ?
antisense  box  cdc53  cdk2  cip1  complex  cul  cullin  deregulation  e3  g1  hallmark  kip1  ligase  lived  member  oligodeoxynucleotides  oligonucleotides  p19  p21  p27  p45  proteolysis  raises  scf  skp1  transformed  ubiquitin  waf1 
13q14  16q22  18q21  1p35  22p  22q  3p22  5q21  8p  9p21  apc  cent  crc  crcs  dcc  dukes  existed  frequencies  heterozygosity  loh  microsatellite  pairwise  q14  q22  rer  sporadic  ucacrc  ucacrcs  ulcerative 
Tagcloud (Intersection) ?