SHB and ZAP70

  • Number of citations of the paper that reports this interaction (PMID 12084069)
  • 3
  • Data Source:
  • BioGRID (affinity chromatography technology, pull down)
  • HPRD (in vitro, in vivo)

SHB

ZAP70

Gene Name Src homology 2 domain containing adaptor protein B zeta-chain (TCR) associated protein kinase 70kDa
Image No pdb structure
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 18 interactors: CRK EPS8 GRAP2 GRB2 IL2RB IL2RG JAK1 JAK3 KDR LAT LCP2 PDGFRA PIK3R1 PLCG1 SLC39A1 SRC VAV1 ZAP70 58 interactors: ABL1 ACP1 ANAPC11 APP ASB3 CARD11 CBL CBLB CBLC CD247 CD3E CD5 CD79B CRK CSK DBNL DEF6 DUSP3 EGFR ERBB3 FCGR3A FCRL3 FYN GAB2 GRB2 IFNAR1 LAT LAX1 LCK LCP2 MUC1 NDUFB8 NFAM1 NR0B2 PAG1 PLCG1 PRLR PTK2B PTPN22 PTPN3 PTPN6 PTPRC RASA1 SH2B3 SH3BP2 SHB SHC1 SIT1 SLA SLA2 SLAMF6 SOS1 TUBA1A TUBA4A TUBB TYROBP VAV1 WIPF1
Entrez ID 6461 7535
HPRD ID 02635 01495
Ensembl ID ENSG00000115085
Uniprot IDs Q15464 P43403
PDB IDs 1FBV 1M61 1U59 2CBL 2OQ1 2OZO 2Y1N 3ZNI 4A4B 4A4C 4K2R
Enriched GO Terms of Interacting Partners?
Tagcloud ?
associate  clone  cloning  csk  cytokine  element  elk  far  fos  gh  ghr  grb10  grb4  hepatoma  huh  library  member  p85  phosphatidylinositol  radiolabeled  reporter  screen  sh2  shc  spi2  stat5  superfamily  transducers  transfections 
cd3  coimmunoprecipitated  compartment  cytosol  detergent  failing  grb2  hsos1  insoluble  jurkat  localize  nonidet  p145  p21ras  p36  p95  participates  particulate  phospholipase  phosphoprotein  plc  redistributed  shc  tcr  vav  vicinity  zeta 
Tagcloud (Difference) ?
associate  clone  cloning  csk  cytokine  element  elk  far  fos  gh  ghr  grb10  grb4  hepatoma  huh  library  member  p85  phosphatidylinositol  radiolabeled  reporter  screen  sh2  spi2  stat5  superfamily  transducers  transfections 
cd3  coimmunoprecipitated  compartment  cytosol  detergent  failing  grb2  hsos1  insoluble  jurkat  localize  nonidet  p145  p21ras  p36  p95  participates  particulate  phospholipase  phosphoprotein  plc  redistributed  tcr  vav  vicinity  zeta 
Tagcloud (Intersection) ?
shc