SCOC and ARL1

Number of citations of the paper that reports this interaction (PubMedID 11303027)
0

Data Source:
HPRD (in vitro)

		SCOC	ARL1
Description		short coiled-coil protein	ARF like GTPase 1
Image
GO Annotations	Cellular Component	Golgi Membrane Nucleoplasm Cytoplasm Endosome Golgi Apparatus Trans-Golgi Network Cytosol Membrane	Golgi Membrane Cytoplasm Golgi Apparatus Trans-Golgi Network Cytosol Membrane Trans-Golgi Network Membrane
	Molecular Function	Protein Binding	Nucleotide Binding GTPase Activity Protein Binding GTP Binding Enzyme Activator Activity Protein Domain Specific Binding Metal Ion Binding Phospholipase D Activator Activity
	Biological Process	Positive Regulation Of Macroautophagy Regulation Of Protein Complex Stability	Intracellular Protein Transport Golgi Organization Toxin Metabolic Process Vesicle-mediated Transport Protein Localization To Golgi Apparatus Retrograde Transport, Endosome To Golgi
Pathways		Retrograde transport at the Trans-Golgi-Network	Retrograde transport at the Trans-Golgi-Network
Drugs			Guanosine-5'-Diphosphate
Diseases
GWAS		Malaria ( 31844061) Smoking status (ever vs never smokers) ( 30643258)	Lung cancer in never smokers ( 28604730) Response to methotrexate in juvenile idiopathic arthritis ( 24709693)
Interacting Genes		14 interacting genes: ARL1 BFSP2 DDIT4L DOK5 FEZ1 ITSN1 KIFC3 KRT40 MAPK8 PSMC5 SCHIP1 SIKE1 TCF4 TRAPPC6A	8 interacting genes: ARFIP2 COPG2 DRD2 GCC1 GCC2 GOLGA1 GOLGA4 SCOC
Entrez ID		60592	400
HPRD ID		18027	04574
Ensembl ID		ENSG00000153130	ENSG00000120805
Uniprot IDs		A0A0C4DGB0 A0A804E055 Q9UIL1	B4DZG7 P40616
PDB IDs		4BWD 7AA7	1UPT 4DCN 5EE5 5J5C
Enriched GO Terms of Interacting Partners?			Golgi Apparatus Golgi Membrane Trans-Golgi Network Small GTPase Binding Golgi To Plasma Membrane Protein Transport Golgi Vesicle Transport Establishment Of Protein Localization To Plasma Membrane Golgi To Plasma Membrane Transport Intracellular Protein Localization Membrane Negative Regulation Of Circadian Sleep/wake Cycle, Sleep G Protein-coupled Receptor Complex Dopamine Neurotransmitter Receptor Activity, Coupled Via Gi/Go Positive Regulation Of Renal Sodium Excretion Positive Regulation Of Glial Cell-derived Neurotrophic Factor Production Positive Regulation Of Dopamine Uptake Involved In Synaptic Transmission Orbitofrontal Cortex Development Negative Regulation Of Dopamine Secretion Vesicle-mediated Transport Negative Regulation Of Dopamine Receptor Signaling Pathway Acrosomal Vesicle Cytosol Vesicle-mediated Transport To The Plasma Membrane Protein Transport Establishment Of Protein Localization Post-Golgi Vesicle-mediated Transport Recycling Endosome To Golgi Transport Intracellular Protein Transport Membrane Curvature Sensor Activity Dopamine Binding Dopamine Neurotransmitter Receptor Activity Cerebral Cortex GABAergic Interneuron Migration Dopamine Uptake Involved In Synaptic Transmission Adenylate Cyclase-inhibiting Dopamine Receptor Signaling Pathway Negative Regulation Of Dephosphorylation Beta-arrestin-dependent Dopamine Receptor Signaling Pathway Hyaloid Vascular Plexus Regression Branching Morphogenesis Of A Nerve Positive Regulation Of Neurotransmitter Uptake Regulation Of Locomotion Involved In Locomotory Behavior Positive Regulation Of Developmental Growth Late Endosome To Golgi Transport Regulation Of Synapse Structural Plasticity Regulation Of Renal Sodium Excretion Interneuron Migration From The Subpallium To The Cortex Regulation Of Dopamine Uptake Involved In Synaptic Transmission Heterotrimeric G-protein Binding Nervous System Process Involved In Regulation Of Systemic Arterial Blood Pressure Phospholipase C-activating Dopamine Receptor Signaling Pathway Establishment Of Localization In Cell
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