MAGEA1 and MIEF1

Number of citations: 50 (PubMedID 32296183)
Data Source: BioGRID (two hybrid), HPRD (two hybrid)

		MAGEA1	MIEF1
Name		MAGE family member A1	mitochondrial elongation factor 1
Structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Plasma Membrane	Mitochondrion Mitochondrial Outer Membrane Peroxisome Membrane
	Molecular Function	Protein Binding Histone Deacetylase Binding	Nucleotide Binding Protein Binding GDP Binding Identical Protein Binding ADP Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Notch Signaling Pathway	Mitochondrial Fission Mitochondrion Organization Mitochondrial Fusion Positive Regulation Of Mitochondrial Fusion Positive Regulation Of Mitochondrial Fission Positive Regulation Of Protein Targeting To Membrane
Pathways		None	Mitochondrial ribosome-associated quality control
GWAS		No GWAS studies recorded	Liver enzyme levels (alkaline phosphatase) ( 33972514 ) Mean corpuscular hemoglobin ( 32888494 )
Interacting Genes		25 interacting genes: ABI2 CEP57L1 DNM1L HDAC1 HLA-A HLA-B HYPK LRSAM1 MDM4 MIEF1 NOTCH1 PBX3 PCGF6 RAB17 RNF166 S100A9 SELPLG SFN SGK1 SH3GLB2 SHFL SNW1 TRIM31 UQCRB ZNF564	22 interacting genes: ABHD5 AGTRAP ARFIP2 ATP5PF CMTM5 CMTM6 DNM1L FAM25A FAM25C FAM25G HTATIP2 MAGEA1 MED21 PLIN3 PRAF2 PRR4 PSMA1 SYP TNFRSF10D UBQLN1 UBQLN2 YWHAG
Entrez ID		4100	54471
HPRD ID		02059	13371
Ensembl ID		ENSG00000198681	ENSG00000100335
Uniprot IDs		P43355	B0QY95 Q9NQG6
PDB IDs		1W72 3BO8	4NXT 4NXU 4NXV 4NXW 4NXX 5X9B 5X9C
GO Terms Enriched among Interactors		TAP Binding Compartment Pattern Specification Protection From Natural Killer Cell Mediated Cytotoxicity MHC Class I Protein Complex Detection Of Bacterium Antigen Processing And Presentation Of Endogenous Peptide Antigen Via MHC Class I Via ER Pathway, TAP-independent Antigen Processing And Presentation Of Endogenous Peptide Antigen Via MHC Class Ib Mitochondrial Fission Regulation Of Cellular Component Organization Response To External Biotic Stimulus Epidermal Cell Differentiation Negative Regulation Of Innate Immune Response Negative Regulation Of Myotube Differentiation Innate Immune Response Recycling Endosome Membrane Antigen Processing And Presentation Of Endogenous Peptide Antigen Via MHC Class I Atrioventricular Valve Morphogenesis Endocardial Cushion Morphogenesis Positive Regulation Of Mitochondrial Fission Defense Response Host-mediated Perturbation Of Symbiont Process Notch Binding Negative Regulation Of Natural Killer Cell Mediated Cytotoxicity Defense Response To Symbiont Modulation Of Process Of Another Organism Defense Response To Other Organism Response To Other Organism Positive Regulation Of Epidermal Cell Differentiation Host-mediated Perturbation Of Viral Transcription Antigen Processing And Presentation Of Endogenous Antigen Regulation Of Mitochondrial Fission Lumenal Side Of Endoplasmic Reticulum Membrane Autophagy Detection Of Biotic Stimulus Positive Regulation Of Epidermis Development Endoderm Development Regulation Of Viral Process Positive Regulation Of Glial Cell Differentiation Positive Regulation Of T Cell Mediated Cytotoxicity Immune Response Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I Peptide Antigen Binding Notch Signaling Pathway Involved In Regulation Of Secondary Heart Field Cardioblast Proliferation Venous Endothelial Cell Differentiation Coronary Sinus Valve Morphogenesis Foregut Morphogenesis Posterior Compartment Specification Anterior Compartment Pattern Formation S100A9 Complex Viral Process	None