MAGEA1 and SH3GLB2

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		MAGEA1	SH3GLB2
Gene Name		melanoma antigen family A, 1	SH3-domain GRB2-like endophilin B2
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Plasma Membrane	Nucleus Nucleoplasm Cytoplasm
	Molecular Function	Protein Binding Histone Deacetylase Binding	Protein Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated Negative Regulation Of Notch Signaling Pathway
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		18 interactors: C19orf66 CEP57L1 DNM1L HDAC1 HLA-A HLA-B HYPK MIEF1 PBX3 RAB17 SELPLG SFN SGK1 SH3GLB2 SNW1 TRIM31 UQCRB ZNF564	8 interactors: CCDC158 GADD45G GIT2 KDM1A MAGEA1 SH3GLB1 SH3KBP1 SREK1
Entrez ID		4100	56904
HPRD ID		02059	15334
Ensembl ID		ENSG00000198681	ENSG00000148341
Uniprot IDs		P43355	B7ZC38 Q9NR46
PDB IDs		1W72 3BO8
Enriched GO Terms of Interacting Partners?		Antigen Processing And Presentation Of Endogenous Peptide Antigen Via MHC Class I Via ER Pathway, TAP-independent Protection From Natural Killer Cell Mediated Cytotoxicity Negative Regulation Of Natural Killer Cell Mediated Cytotoxicity Positive Regulation Of Mitochondrion Organization Regulation Of Viral Transcription Positive Regulation Of Mitochondrial Fission Interferon-gamma-mediated Signaling Pathway Antigen Processing And Presentation Of Endogenous Peptide Antigen Via MHC Class I Regulation Of Mitochondrion Organization Regulation Of Mitochondrial Fission Antigen Processing And Presentation Of Endogenous Antigen Cellular Response To Interferon-gamma Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I, TAP-independent Response To Interferon-gamma Negative Regulation Of Viral Transcription Detection Of Bacterium Positive Regulation Of Organelle Organization Regulation Of Natural Killer Cell Mediated Cytotoxicity Regulation Of Natural Killer Cell Mediated Immunity Regulation Of Viral Process Mitochondrial Fission Detection Of Biotic Stimulus Release Of Cytochrome C From Mitochondria Interaction With Symbiont Viral Process Negative Regulation Of Innate Immune Response Positive Regulation Of T Cell Mediated Cytotoxicity Cellular Response To Cytokine Stimulus Regulation Of T Cell Mediated Cytotoxicity Response To Stress Cellular Response To Organic Substance Positive Regulation Of Leukocyte Mediated Cytotoxicity Response To Cytokine Mitochondrial Membrane Fission Posterior Compartment Specification Anterior Compartment Pattern Formation Dynamin Polymerization Involved In Mitochondrial Fission Positive Regulation Of T Cell Mediated Immunity Positive Regulation Of Cell Killing Regulation Of Cellular Component Organization Regulation Of Leukocyte Mediated Cytotoxicity Type I Interferon Signaling Pathway Cellular Response To Type I Interferon Positive Regulation Of Transport Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I, TAP-dependent Response To Type I Interferon Apoptotic Mitochondrial Changes Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I Negative Regulation Of Viral Process Positive Regulation Of Protein Transport	Regulation Of Primitive Erythrocyte Differentiation Regulation Of Signal Transduction Regulation Of Signaling Apoptotic Process Negative Regulation Of Histone H3-K4 Methylation Histone H3-K9 Demethylation Histone H3-K4 Demethylation Programmed Cell Death Activation Of MAPKKK Activity Positive Regulation Of P38MAPK Cascade Cell Death Death Negative Regulation Of Signal Transduction Positive Regulation Of Megakaryocyte Differentiation Positive Regulation Of Hormone Biosynthetic Process Negative Regulation Of Signaling Negative Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Negative Regulation Of Histone H3-K9 Methylation Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Negative Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Regulation Of P38MAPK Cascade Granulocyte Differentiation Regulation Of Megakaryocyte Differentiation Negative Regulation Of Histone Methylation Positive Regulation Of Protein Oligomerization Positive Regulation Of Erythrocyte Differentiation Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Behavioral Response To Pain Regulation Of Histone H3-K4 Methylation
Tagcloud ?		acrbp antigens attractive chemoradiation ctag1b ctag2 embedded encountered excision formalin frozen germ homogenous immunogenic immunotherapy lage liposarcoma liposarcomas mainstay myxoid paraffin prame real round ssx2 testicular testis	analyse code crat ctsd ejaculated ejaculates elongating fertile fertilisation flna g6pd gapdh h3k9ac infertile intergenic mcf2l plxna3 protamines semen semiquantitative sox2 sperm spermatids spermatocytes spermatogenesis spermatogonia spermatozoa stk11ip testicular
Tagcloud (Difference) ?		acrbp antigens attractive chemoradiation ctag1b ctag2 embedded encountered excision formalin frozen germ homogenous immunogenic immunotherapy lage liposarcoma liposarcomas mainstay myxoid paraffin prame real round ssx2 testis	analyse code crat ctsd ejaculated ejaculates elongating fertile fertilisation flna g6pd gapdh h3k9ac infertile intergenic mcf2l plxna3 protamines semen semiquantitative sox2 sperm spermatids spermatocytes spermatogenesis spermatogonia spermatozoa stk11ip
Tagcloud (Intersection) ?		testicular