MAGEA1 and RAB17

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		MAGEA1	RAB17
Gene Name		melanoma antigen family A, 1	RAB17, member RAS oncogene family
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Plasma Membrane	Intracellular Early Endosome Plasma Membrane Basolateral Plasma Membrane Apical Plasma Membrane Endocytic Vesicle Dendrite Melanosome Neuronal Cell Body Recycling Endosome Recycling Endosome Membrane Extracellular Vesicular Exosome
	Molecular Function	Protein Binding Histone Deacetylase Binding	GTPase Activity Protein Binding GTP Binding GDP Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated Negative Regulation Of Notch Signaling Pathway	Immunoglobulin Transcytosis In Epithelial Cells Mediated By Polymeric Immunoglobulin Receptor Intracellular Protein Transport Regulation Of Endocytosis Establishment Of Melanosome Localization Melanosome Transport Endocytic Recycling Rab Protein Signal Transduction Cilium Assembly Transcytosis Filopodium Assembly Regulation Of Dendrite Development Regulation Of Filopodium Assembly Regulation Of Synapse Assembly
Pathways
Drugs
Diseases
GWAS			Obesity-related traits ( 23251661)
Protein-Protein Interactions		18 interactors: C19orf66 CEP57L1 DNM1L HDAC1 HLA-A HLA-B HYPK MIEF1 PBX3 RAB17 SELPLG SFN SGK1 SH3GLB2 SNW1 TRIM31 UQCRB ZNF564	9 interactors: ACVR1 C11orf49 FAM9B MAGEA1 NUDT3 RAB7A RABAC1 S100A8 SMURF2
Entrez ID		4100	64284
HPRD ID		02059	11468
Ensembl ID		ENSG00000198681	ENSG00000124839
Uniprot IDs		P43355	Q6PJZ0 Q9H0T7
PDB IDs		1W72 3BO8
Enriched GO Terms of Interacting Partners?		Antigen Processing And Presentation Of Endogenous Peptide Antigen Via MHC Class I Via ER Pathway, TAP-independent Protection From Natural Killer Cell Mediated Cytotoxicity Negative Regulation Of Natural Killer Cell Mediated Cytotoxicity Positive Regulation Of Mitochondrion Organization Regulation Of Viral Transcription Positive Regulation Of Mitochondrial Fission Interferon-gamma-mediated Signaling Pathway Antigen Processing And Presentation Of Endogenous Peptide Antigen Via MHC Class I Regulation Of Mitochondrion Organization Regulation Of Mitochondrial Fission Antigen Processing And Presentation Of Endogenous Antigen Cellular Response To Interferon-gamma Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I, TAP-independent Response To Interferon-gamma Negative Regulation Of Viral Transcription Detection Of Bacterium Positive Regulation Of Organelle Organization Regulation Of Natural Killer Cell Mediated Cytotoxicity Regulation Of Natural Killer Cell Mediated Immunity Regulation Of Viral Process Mitochondrial Fission Detection Of Biotic Stimulus Release Of Cytochrome C From Mitochondria Interaction With Symbiont Viral Process Negative Regulation Of Innate Immune Response Positive Regulation Of T Cell Mediated Cytotoxicity Cellular Response To Cytokine Stimulus Regulation Of T Cell Mediated Cytotoxicity Response To Stress Cellular Response To Organic Substance Positive Regulation Of Leukocyte Mediated Cytotoxicity Response To Cytokine Mitochondrial Membrane Fission Posterior Compartment Specification Anterior Compartment Pattern Formation Dynamin Polymerization Involved In Mitochondrial Fission Positive Regulation Of T Cell Mediated Immunity Positive Regulation Of Cell Killing Regulation Of Cellular Component Organization Regulation Of Leukocyte Mediated Cytotoxicity Type I Interferon Signaling Pathway Cellular Response To Type I Interferon Positive Regulation Of Transport Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I, TAP-dependent Response To Type I Interferon Apoptotic Mitochondrial Changes Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I Negative Regulation Of Viral Process Positive Regulation Of Protein Transport	Negative Regulation Of Signal Transduction Negative Regulation Of Signaling Regulation Of Signal Transduction Acute Inflammatory Response BMP Signaling Pathway Regulation Of Signaling Diphosphoinositol Polyphosphate Catabolic Process Diadenosine Polyphosphate Catabolic Process Epidermal Growth Factor Catabolic Process Endocardial Cushion Cell Fate Commitment Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Catabolic Process Neutrophil Aggregation Transforming Growth Factor Beta Receptor Signaling Pathway Cellular Response To Transforming Growth Factor Beta Stimulus Response To Transforming Growth Factor Beta Phagosome-lysosome Fusion Sequestering Of Zinc Ion Phagosome Acidification Mitral Valve Morphogenesis Cardiac Muscle Cell Fate Commitment Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Mitral Valve Development Ubiquitin-dependent SMAD Protein Catabolic Process Protein To Membrane Docking Positive Regulation Of Determination Of Dorsal Identity Negative Regulation Of Activin Receptor Signaling Pathway Atrial Septum Primum Morphogenesis Chemokine Production Endocardial Cell Differentiation Sequestering Of Metal Ion Positive Regulation Of Signal Transduction Positive Regulation Of Secretion Septum Primum Development Positive Regulation Of Exosomal Secretion Regulation Of Exosomal Secretion Protein Targeting To Lysosome Pathway-restricted SMAD Protein Phosphorylation Chronic Inflammatory Response Phagolysosome Assembly Protein Localization To Lysosome Cellular Zinc Ion Homeostasis Regulation Of Autophagic Vacuole Assembly Zinc Ion Homeostasis Leukocyte Migration Involved In Inflammatory Response Muscle Cell Fate Commitment Inflammatory Response Pharyngeal System Development Regulation Of Vacuole Organization Endocardium Development
Tagcloud ?		acrbp antigens attractive chemoradiation ctag1b ctag2 embedded encountered excision formalin frozen germ homogenous immunogenic immunotherapy lage liposarcoma liposarcomas mainstay myxoid paraffin prame real round ssx2 testicular testis	accessibility acclimation acetyl altogether catalyze cold deacetylases deacetylation demethylation drought hdacs histones hyperacetylation hypoacetylated ice1 maize methylated micrococcal mnase nuclease repressor responding stresses trichostatin tsa zmcor413 zmdbf1 zmdreb1 zmice1
Tagcloud (Difference) ?		acrbp antigens attractive chemoradiation ctag1b ctag2 embedded encountered excision formalin frozen germ homogenous immunogenic immunotherapy lage liposarcoma liposarcomas mainstay myxoid paraffin prame real round ssx2 testicular testis	accessibility acclimation acetyl altogether catalyze cold deacetylases deacetylation demethylation drought hdacs histones hyperacetylation hypoacetylated ice1 maize methylated micrococcal mnase nuclease repressor responding stresses trichostatin tsa zmcor413 zmdbf1 zmdreb1 zmice1
Tagcloud (Intersection) ?