MAGEA1 and SNW1

Number of citations of the paper that reports this interaction (PMID 15316101)
15

Data Source:
BioGRID (two hybrid, affinity chromatography technology, pull down)
HPRD (in vivo, two hybrid)

		MAGEA1	SNW1
Gene Name		melanoma antigen family A, 1	SNW domain containing 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Plasma Membrane	Chromatin Nucleus Nucleoplasm Spliceosomal Complex Positive Transcription Elongation Factor Complex B Nuclear Matrix Catalytic Step 2 Spliceosome SMAD3-SMAD4 Protein Complex
	Molecular Function	Protein Binding Histone Deacetylase Binding	Transcription Coactivator Activity Transcription Corepressor Activity Notch Binding Protein Binding Nuclear Hormone Receptor Binding Vitamin D Receptor Binding Retinoic Acid Receptor Binding Poly(A) RNA Binding SMAD Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated Negative Regulation Of Notch Signaling Pathway	Negative Regulation Of Transcription From RNA Polymerase II Promoter MRNA Splicing, Via Spliceosome Regulation Of Transcription From RNA Polymerase II Promoter Transcription Initiation From RNA Polymerase II Promoter Notch Signaling Pathway Gene Expression Viral Process Positive Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Positive Regulation By Host Of Viral Transcription Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of MRNA Splicing, Via Spliceosome Retinoic Acid Receptor Signaling Pathway Regulation Of Retinoic Acid Receptor Signaling Pathway Positive Regulation Of Neurogenesis Positive Regulation Of Histone H3-K4 Methylation Regulation Of Vitamin D Receptor Signaling Pathway Positive Regulation Of Vitamin D Receptor Signaling Pathway Cellular Response To Retinoic Acid
Pathways			Signaling by NOTCH1 HD Domain Mutants in Cancer Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer Signaling by NOTCH Notch-HLH transcription pathway Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant NOTCH1 Intracellular Domain Regulates Transcription Generic Transcription Pathway Pre-NOTCH Transcription and Translation Signaling by NOTCH1 Pre-NOTCH Expression and Processing Signaling by NOTCH1 PEST Domain Mutants in Cancer Signaling by NOTCH1 in Cancer Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants Constitutive Signaling by NOTCH1 PEST Domain Mutants FBXW7 Mutants and NOTCH1 in Cancer
Drugs
Diseases
GWAS			Response to platinum-based chemotherapy in non-small-cell lung cancer ( 22872573)
Protein-Protein Interactions		18 interactors: C19orf66 CEP57L1 DNM1L HDAC1 HLA-A HLA-B HYPK MIEF1 PBX3 RAB17 SELPLG SFN SGK1 SH3GLB2 SNW1 TRIM31 UQCRB ZNF564	58 interactors: ACTN2 ASCC2 CEP55 CIR1 CXorf56 DAXX EP300 GOLGA2 HDAC2 IKBKG IKZF1 JDP2 KRT40 LRP2BP LZTS2 MAGEA1 MAPK6 MEN1 MFAP1 MSL1 MTUS2 NCOR1 NCOR2 NHP2L1 NOTCH1 NOTCH3 NR0B1 NR0B2 PABPN1 PCBD2 PGR PPIL1 PRKAA2 RARA RB1 RBL1 RBL2 RBPJ RINT1 RXRA SART1 SIN3A SIRT1 SKI SMAD2 SMAD3 SMAD4 SRC TEX11 TFIP11 TNNT1 TOP1 TRAF1 TRIM15 TTC14 VAV2 VDR ZSCAN1
Entrez ID		4100	22938
HPRD ID		02059	04340
Ensembl ID		ENSG00000198681	ENSG00000100603
Uniprot IDs		P43355	G3V3A4 Q13573
PDB IDs		1W72 3BO8
Enriched GO Terms of Interacting Partners?		Antigen Processing And Presentation Of Endogenous Peptide Antigen Via MHC Class I Via ER Pathway, TAP-independent Protection From Natural Killer Cell Mediated Cytotoxicity Negative Regulation Of Natural Killer Cell Mediated Cytotoxicity Positive Regulation Of Mitochondrion Organization Regulation Of Viral Transcription Positive Regulation Of Mitochondrial Fission Interferon-gamma-mediated Signaling Pathway Antigen Processing And Presentation Of Endogenous Peptide Antigen Via MHC Class I Regulation Of Mitochondrion Organization Regulation Of Mitochondrial Fission Antigen Processing And Presentation Of Endogenous Antigen Cellular Response To Interferon-gamma Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I, TAP-independent Response To Interferon-gamma Negative Regulation Of Viral Transcription Detection Of Bacterium Positive Regulation Of Organelle Organization Regulation Of Natural Killer Cell Mediated Cytotoxicity Regulation Of Natural Killer Cell Mediated Immunity Regulation Of Viral Process Mitochondrial Fission Detection Of Biotic Stimulus Release Of Cytochrome C From Mitochondria Interaction With Symbiont Viral Process Negative Regulation Of Innate Immune Response Positive Regulation Of T Cell Mediated Cytotoxicity Cellular Response To Cytokine Stimulus Regulation Of T Cell Mediated Cytotoxicity Response To Stress Cellular Response To Organic Substance Positive Regulation Of Leukocyte Mediated Cytotoxicity Response To Cytokine Mitochondrial Membrane Fission Posterior Compartment Specification Anterior Compartment Pattern Formation Dynamin Polymerization Involved In Mitochondrial Fission Positive Regulation Of T Cell Mediated Immunity Positive Regulation Of Cell Killing Regulation Of Cellular Component Organization Regulation Of Leukocyte Mediated Cytotoxicity Type I Interferon Signaling Pathway Cellular Response To Type I Interferon Positive Regulation Of Transport Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I, TAP-dependent Response To Type I Interferon Apoptotic Mitochondrial Changes Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I Negative Regulation Of Viral Process Positive Regulation Of Protein Transport	Transcription Initiation From RNA Polymerase II Promoter DNA-templated Transcription, Initiation Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Transcription, DNA-templated Negative Regulation Of Transcription From RNA Polymerase II Promoter RNA Metabolic Process Negative Regulation Of Gene Expression RNA Biosynthetic Process Gene Expression Negative Regulation Of Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Gene Expression Nucleobase-containing Compound Metabolic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Transcription From RNA Polymerase II Promoter Regulation Of Transcription, DNA-templated Regulation Of Nitrogen Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Nitrogen Compound Metabolic Process Macromolecule Biosynthetic Process Negative Regulation Of Cellular Metabolic Process Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Gene Expression Biosynthetic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Regulation Of Metabolic Process Positive Regulation Of Cellular Biosynthetic Process Cellular Response To Organic Substance Transforming Growth Factor Beta Receptor Signaling Pathway Chromatin Organization Chromatin Modification Organ Development Regulation Of Signal Transduction Cellular Response To Transforming Growth Factor Beta Stimulus Regulation Of Signaling Regulation Of Binding Response To Transforming Growth Factor Beta Positive Regulation Of Metabolic Process Cell Cycle Chromosome Organization Negative Regulation Of Cell Differentiation
Tagcloud ?		acrbp antigens attractive chemoradiation ctag1b ctag2 embedded encountered excision formalin frozen germ homogenous immunogenic immunotherapy lage liposarcoma liposarcomas mainstay myxoid paraffin prame real round ssx2 testicular testis	buffer complicates consist demonstration deprotection ends exploit feasibility foci knock nucleoprotein pot1 pseudogene rap1 repetitive scaling shelterin shortening skiip telomere telomeres telomeric tif tin2 tpp1 trf1 trf2 ttaggg visualized
Tagcloud (Difference) ?		acrbp antigens attractive chemoradiation ctag1b ctag2 embedded encountered excision formalin frozen germ homogenous immunogenic immunotherapy lage liposarcoma liposarcomas mainstay myxoid paraffin prame real round ssx2 testicular testis	buffer complicates consist demonstration deprotection ends exploit feasibility foci knock nucleoprotein pot1 pseudogene rap1 repetitive scaling shelterin shortening skiip telomere telomeres telomeric tif tin2 tpp1 trf1 trf2 ttaggg visualized
Tagcloud (Intersection) ?