ANP32A and NSFL1C

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
HPRD (two hybrid)

		ANP32A	NSFL1C
Gene Name		acidic (leucine-rich) nuclear phosphoprotein 32 family, member A	NSFL1 (p97) cofactor (p47)
Image
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Endoplasmic Reticulum Perinuclear Region Of Cytoplasm	Nucleoplasm Chromosome Cytoplasm Golgi Stack Cytosol Plasma Membrane Intermediate Filament Cytoskeleton
	Molecular Function	Protein Binding Poly(A) RNA Binding	Protein Binding Lipid Binding Protein Phosphatase Type 1 Regulator Activity Ubiquitin Binding
	Biological Process	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Nucleocytoplasmic Transport Gene Expression Intracellular Signal Transduction	Autophagic Vacuole Assembly Golgi Organization Nuclear Envelope Reassembly Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Regulation Of Catalytic Activity Membrane Fusion
Pathways		Regulation of mRNA stability by proteins that bind AU-rich elements HuR stabilizes mRNA
Drugs
Diseases
GWAS		Esophageal cancer ( 21642993)
Protein-Protein Interactions		27 interactors: ADAP1 APEX1 ATXN1 AXIN1 CHAF1A E4F1 ELAVL1 HIST1H3A HIST1H4A HIST2H2AC HIST2H2BE HIST3H3 HIST4H4 HSPB3 KPNA1 KPNA5 KPNA6 MAP1B NSFL1C PCBP1 PGR PPARG PTPRC SET TAF1A THRB XPO1	14 interactors: ANP32A CDK1 DBI FAM32A GLMN GSK3B LIPE NGLY1 PHAX RPL22 SRP14 STX5 TARDBP VCP
Entrez ID		8125	55968
HPRD ID		09014	09425
Ensembl ID		ENSG00000140350	ENSG00000088833
Uniprot IDs		P39687	Q53FE8 Q9UNZ2
PDB IDs		2JE0 2JE1	1SS6
Enriched GO Terms of Interacting Partners?		DNA Replication-dependent Nucleosome Assembly Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Chromatin Silencing At RDNA Nucleosome Assembly Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Chromatin Assembly Negative Regulation Of Transcription, DNA-templated Nucleocytoplasmic Transport Nuclear Transport Nucleosome Organization Chromatin Assembly Or Disassembly Protein-DNA Complex Assembly DNA Packaging Chromatin Silencing Negative Regulation Of Cellular Metabolic Process DNA Methylation On Cytosine Cytoplasmic Transport DNA Conformation Change Gene Expression DNA Metabolic Process Negative Regulation Of Gene Expression, Epigenetic NLS-bearing Protein Import Into Nucleus Telomere Maintenance Regulation Of Nitrogen Compound Metabolic Process DNA Modification Regulation Of Gene Expression, Epigenetic Nucleobase-containing Compound Metabolic Process Cellular Macromolecular Complex Assembly Gene Silencing Regulation Of Metabolic Process Histone H4-K20 Demethylation Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Gene Expression Chromosome Organization Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Negative Regulation Of Megakaryocyte Differentiation Regulation Of RNA Metabolic Process Intracellular Transport Protein Localization To Nucleus DNA Methylation Nitrogen Compound Metabolic Process Demethylation Negative Regulation Of Hematopoietic Progenitor Cell Differentiation Organelle Organization	Cytoplasmic Transport Regulation Of Protein Catabolic Process Positive Regulation Of Protein Catabolic Process Intracellular Transport Cellular Localization Positive Regulation Of Protein Transport Protein Localization Establishment Of Localization In Cell Cellular Protein Localization Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process Protein Transport Positive Regulation Of Cellular Protein Catabolic Process Establishment Of Protein Localization Response To Endoplasmic Reticulum Stress Intracellular Protein Transport Protein Localization To Organelle Regulation Of Proteasomal Protein Catabolic Process Regulation Of Protein Transport Nucleocytoplasmic Transport Nuclear Transport Regulation Of Proteolysis Positive Regulation Of Protein Metabolic Process Regulation Of Establishment Of Protein Localization Positive Regulation Of Proteolysis Positive Regulation Of Lys63-specific Deubiquitinase Activity Positive Regulation Of Protein K63-linked Deubiquitination Pronuclear Fusion Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Cellular Response To Heat Positive Regulation Of Transport Positive Regulation Of Proteasomal Protein Catabolic Process Muscle Cell Differentiation Regulation Of Protein Localization Organelle Fusion Cellular Macromolecule Catabolic Process Negative Regulation Of Type B Pancreatic Cell Development SnRNA Export From Nucleus Superior Temporal Gyrus Development Membrane Organization SRP-dependent Cotranslational Protein Targeting To Membrane Triglyceride Metabolic Process Cotranslational Protein Targeting To Membrane ER To Golgi Vesicle-mediated Transport Protein Targeting To ER Establishment Of Protein Localization To Endoplasmic Reticulum Neutral Lipid Metabolic Process Re-entry Into Mitotic Cell Cycle Golgi Disassembly Negative Regulation Of Neuron Maturation
Tagcloud ?		achn brdu capg capping chd4 chromodomain coded constrast cyclind1 helicase icpl illustrated isotope judged lentivirus lysates miapaca2 p53wt pp32 pp32r1 pp32r1y140h proteome r248w reside reverted shuttling transduced untransduced	anxa4 cacybp cfl1 ciapin1 ctro cytokinesis fam50a hspb1 incapable mefs migrated nbs ndrg ndrg1 ndrg1expression pcbp2 pdap1 pml proliferate proliferated relay rsu1 stations stmn1 sumo2 tpd52l2 trio ube2m ywhag
Tagcloud (Difference) ?		achn brdu capg capping chd4 chromodomain coded constrast cyclind1 helicase icpl illustrated isotope judged lentivirus lysates miapaca2 p53wt pp32 pp32r1 pp32r1y140h proteome r248w reside reverted shuttling transduced untransduced	anxa4 cacybp cfl1 ciapin1 ctro cytokinesis fam50a hspb1 incapable mefs migrated nbs ndrg ndrg1 ndrg1expression pcbp2 pdap1 pml proliferate proliferated relay rsu1 stations stmn1 sumo2 tpd52l2 trio ube2m ywhag
Tagcloud (Intersection) ?