PRDM14 and DGCR6

Number of citations of the paper that reports this interaction (PMID 24722188)
1

Data Source:
BioGRID (two hybrid)

		PRDM14	DGCR6
Gene Name		PR domain containing 14	DiGeorge syndrome critical region gene 6
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm	Proteinaceous Extracellular Matrix Nucleus
	Molecular Function	DNA Binding Protein Binding Methyltransferase Activity Metal Ion Binding	Molecular_function
	Biological Process	Cell Morphogenesis Cell Fate Specification Inner Cell Mass Cell Fate Commitment Transcription, DNA-templated Regulation Of Transcription, DNA-templated Germ Cell Development Fertilization Germ-line Stem Cell Maintenance Histone H3-R26 Methylation Somatic Stem Cell Maintenance Regulation Of Gene Expression, Epigenetic Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Regulation Of DNA Methylation Homeostasis Of Number Of Cells Within A Tissue	Cell Adhesion Organ Morphogenesis
Pathways		Transcriptional regulation of pluripotent stem cells
Drugs
Diseases
GWAS		Testicular germ cell tumor ( 23666240)
Protein-Protein Interactions		19 interactors: AKAP9 ATPAF2 BEX2 CBFA2T2 CDCA7L DGCR6 EIF4E2 GPATCH2L HEXIM2 HSPB7 ID3 MIA3 PRKAB2 PSMA1 RAD51D RCOR3 RUNX1T1 TEKT4 TTC32	61 interactors: ADAMTSL4 AES AGTRAP APP ARNT2 C1orf94 C3orf62 CBLL1 CCDC33 CCDC36 CCDC67 CTAGE5 CTBP1 DLGAP2 DLX2 DNPEP DOCK8 EFEMP2 EFHC2 ENKD1 FBF1 GOLGA2 GSE1 HGS HOMEZ IKZF3 KIAA1377 KLHL12 LZTS2 MBIP MEIS2 MEOX2 MID2 MIPOL1 NAB2 NECAB2 NOTCH2NL NQO2 NUP54 NUP62 PDLIM7 PRDM14 RABGEF1 REL RFX6 RIMBP3 SPERT SPRY2 SS18L1 TCF12 TCF4 TFIP11 TRAF1 TRAF2 TRIM27 TUBGCP4 VCP ZBED1 ZC4H2 ZNF398 ZNF446
Entrez ID		63978	8214
HPRD ID		11457	03177
Ensembl ID		ENSG00000147596	ENSG00000183628
Uniprot IDs		Q9GZV8	Q14129
PDB IDs
Enriched GO Terms of Interacting Partners?			RNA Biosynthetic Process Transcription, DNA-templated RNA Metabolic Process Regulation Of Gene Expression Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Positive Regulation Of Gene Expression Gene Expression Regulation Of RNA Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Nitrogen Compound Metabolic Process Macromolecule Biosynthetic Process Positive Regulation Of Metabolic Process Regulation Of Metabolic Process Negative Regulation Of Signal Transduction Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Negative Regulation Of Cellular Metabolic Process Cellular Macromolecule Biosynthetic Process Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Regulation Of Protein Binding Regulation Of ERBB Signaling Pathway Negative Regulation Of Signaling Positive Regulation Of Cellular Metabolic Process Regulation Of Cellular Process Positive Regulation Of Macromolecule Biosynthetic Process Nucleobase-containing Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Regulation Of Cell Death Developmental Process Positive Regulation Of Cellular Biosynthetic Process Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Negative Regulation Of RNA Biosynthetic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Signal Transduction Regulation Of Signaling Negative Regulation Of ERBB Signaling Pathway Regulation Of Apoptotic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Protein Ubiquitination Negative Regulation Of Ras Protein Signal Transduction Negative Regulation Of Small GTPase Mediated Signal Transduction Regulation Of Binding Positive Regulation Of Transcription From RNA Polymerase II Promoter Protein Modification By Small Protein Conjugation Nitrogen Compound Metabolic Process Negative Regulation Of Canonical Wnt Signaling Pathway
Tagcloud ?		adam9 aurka birc5 c11orf30 ccne1 cdc6 cdh1 cpd devoid emsy esr1 fgfr1 holland ikbkb mapt mathematical meaning med1 microdissection mlpa mrc mtdh multiplex numerical p078 qiagen salsa top2a traf4	1rn antidopaminergic daao darpp dgcr2 drd2 drd3 dtnbp1 evolves facets forcefully g72 gabra1 gabra6 gabrp gria1 grin1 grm3 merge mglu2 networking prodh rgs4 slc1a2 slc1a6 underpinned unifying vulnerablility zdhhc8
Tagcloud (Difference) ?		adam9 aurka birc5 c11orf30 ccne1 cdc6 cdh1 cpd devoid emsy esr1 fgfr1 holland ikbkb mapt mathematical meaning med1 microdissection mlpa mrc mtdh multiplex numerical p078 qiagen salsa top2a traf4	1rn antidopaminergic daao darpp dgcr2 drd2 drd3 dtnbp1 evolves facets forcefully g72 gabra1 gabra6 gabrp gria1 grin1 grm3 merge mglu2 networking prodh rgs4 slc1a2 slc1a6 underpinned unifying vulnerablility zdhhc8
Tagcloud (Intersection) ?