PRDM14 and HEXIM2

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		PRDM14	HEXIM2
Gene Name		PR domain containing 14	hexamethylene bis-acetamide inducible 2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm	Nucleus Nucleoplasm Cytoplasm
	Molecular Function	DNA Binding Protein Binding Methyltransferase Activity Metal Ion Binding	Cyclin-dependent Protein Serine/threonine Kinase Inhibitor Activity Protein Binding SnRNA Binding
	Biological Process	Cell Morphogenesis Cell Fate Specification Inner Cell Mass Cell Fate Commitment Transcription, DNA-templated Regulation Of Transcription, DNA-templated Germ Cell Development Fertilization Germ-line Stem Cell Maintenance Histone H3-R26 Methylation Somatic Stem Cell Maintenance Regulation Of Gene Expression, Epigenetic Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Regulation Of DNA Methylation Homeostasis Of Number Of Cells Within A Tissue	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Negative Regulation Of Transcription, DNA-templated
Pathways		Transcriptional regulation of pluripotent stem cells
Drugs
Diseases
GWAS		Testicular germ cell tumor ( 23666240)	Systolic blood pressure ( 19430483)
Protein-Protein Interactions		19 interactors: AKAP9 ATPAF2 BEX2 CBFA2T2 CDCA7L DGCR6 EIF4E2 GPATCH2L HEXIM2 HSPB7 ID3 MIA3 PRKAB2 PSMA1 RAD51D RCOR3 RUNX1T1 TEKT4 TTC32	15 interactors: CCDC36 CCNT1 CDK9 GATA1 MEOX2 PIM1 PIN1 PRDM14 RNPS1 SPRY1 SPRY2 TADA3 TCF12 TERF1 TERF2
Entrez ID		63978	124790
HPRD ID		11457	08129
Ensembl ID		ENSG00000147596	ENSG00000168517
Uniprot IDs		Q9GZV8	Q96MH2
PDB IDs
Enriched GO Terms of Interacting Partners?			Regulation Of Metabolic Process Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Positive Regulation Of Cellular Metabolic Process Cell Cycle Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Telomere Maintenance Via Semi-conservative Replication Negative Regulation Of Cellular Response To Growth Factor Stimulus Regulation Of Nitrogen Compound Metabolic Process Regulation Of Protein Metabolic Process Telomeric Loop Formation Age-dependent Telomere Shortening Regulation Of Protein Phosphorylation Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Telomere Maintenance Via Telomere Shortening Negative Regulation Of Neurotrophin TRK Receptor Signaling Pathway Positive Regulation Of Metabolic Process Negative Regulation Of DNA Replication Regulation Of Cellular Response To Growth Factor Stimulus Regulation Of Phosphorylation Cellular Macromolecule Biosynthetic Process Negative Regulation Of ERK1 And ERK2 Cascade Macromolecule Biosynthetic Process Regulation Of Chromosome Organization Transcription From RNA Polymerase II Promoter Regulation Of Neurotrophin TRK Receptor Signaling Pathway Negative Regulation Of Cellular Metabolic Process Regulation Of Cell Cycle Regulation Of Phosphorus Metabolic Process Positive Regulation Of Gene Expression Replicative Cell Aging Transcription, DNA-templated Regulation Of Nuclear Cell Cycle DNA Replication Telomere Maintenance Via Telomerase Negative Regulation Of Telomere Maintenance Bud Elongation Involved In Lung Branching RNA Biosynthetic Process Nitrogen Compound Metabolic Process Cell Fate Commitment Negative Regulation Of DNA Metabolic Process Mitotic Cell Cycle Process Nucleobase-containing Compound Metabolic Process Chromatin Organization Mitotic Cell Cycle Negative Regulation Of Ras GTPase Activity Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Regulation Of Telomere Maintenance Regulation Of DNA Replication Positive Regulation Of Transcription, DNA-templated
Tagcloud ?		adam9 aurka birc5 c11orf30 ccne1 cdc6 cdh1 cpd devoid emsy esr1 fgfr1 holland ikbkb mapt mathematical meaning med1 microdissection mlpa mrc mtdh multiplex numerical p078 qiagen salsa top2a traf4
Tagcloud (Difference) ?		adam9 aurka birc5 c11orf30 ccne1 cdc6 cdh1 cpd devoid emsy esr1 fgfr1 holland ikbkb mapt mathematical meaning med1 microdissection mlpa mrc mtdh multiplex numerical p078 qiagen salsa top2a traf4
Tagcloud (Intersection) ?