DMRT3 and KRTAP10-8

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		DMRT3	KRTAP10-8
Gene Name		doublesex and mab-3 related transcription factor 3	keratin associated protein 10-8
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus	Keratin Filament
	Molecular Function	Core Promoter Proximal Region Sequence-specific DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Protein Homodimerization Activity Metal Ion Binding Protein Heterodimerization Activity
	Biological Process	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Sex Differentiation Adult Walking Behavior Transmission Of Nerve Impulse Ventral Spinal Cord Interneuron Specification Regulation Of Odontogenesis Of Dentin-containing Tooth Male Sex Differentiation
Pathways
Drugs
Diseases
GWAS		Major depressive disorder ( 23377640)
Protein-Protein Interactions		26 interactors: CCNDBP1 INCA1 KHDRBS3 KRT31 KRT40 KRTAP10-3 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP5-9 MDFI MGAT5B MID2 MTUS2 NOTCH2NL PLSCR1 PSMA3 RBPMS REL SAT1 TCF4 TRAF1 TRIM23 TRIM27 TRIP6 UBASH3B	163 interactors: ACY3 ADAMTSL3 ADAMTSL4 AEN AES ALDH3B1 ALPI APOL6 ASPSCR1 ATG9A BEX2 BMP7 C11orf87 C19orf66 C9orf9 CARHSP1 CARKD CATSPER1 CCDC26 CCNJL CHIC2 CHRD CHRNG CLK4 CNNM3 COL8A1 CRCT1 CREB5 DAAM2 DCX DDX55 DDX6 DERL2 DHRS1 DHX57 DMRT3 DOCK2 EIF4E2 FAH FAM27E3 FAM74A4 FAM76B FBXW5 FOXB1 GFOD1 GLIDR GLP1R GLRX3 GLYAT GNAI2 GNE GOLGA8EP HHEX HOXA1 HPCAL1 HSD3B7 HSPD1 IGSF8 ITGB5 JOSD1 KLHL38 KRT20 KRT83 KRTAP10-3 KRTAP10-7 KRTAP10-9 KRTAP12-1 KRTAP12-2 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP4-7 KRTAP5-6 KRTAP5-9 KRTAP9-2 KRTAP9-4 LCE1B LCE2A LCE2D LCE3C LCE3E LCE4A LINC00656 LOC153684 LRCH4 LUZP4 LYVE1 MAPKBP1 MATN3 MEOX2 MLLT6 MTA1 MXI1 NAB2 NOTCH2NL NUFIP2 OTX1 P2RX7 PCED1A PCSK5 PDE9A PGLS PIGS PKD2 POM121L8P PRKAB2 PRPF31 PRR13 PTGER3 PTPMT1 PTPRH PVR PVRL3 QPRT R3HDM2 RANBP3 RPS28 RTN4RL1 SCNM1 SLC22A23 SLC23A1 SLC25A10 SLC6A20 SMCP SMOC1 SPATA3 SPRY1 SPRY2 STK16 SUSD6 TBC1D16 TBC1D23 THAP10 THAP7 TMEM150A TNIP3 TNP2 TNS2 TRPV6 TXNDC5 TYMSOS TYRO3 UTP23 UXT VPS11 WIF1 WT1 WT1-AS YIPF3 ZBTB24 ZFYVE21 ZNF124 ZNF138 ZNF20 ZNF32 ZNF417 ZNF439 ZNF473 ZNF572 ZNF578 ZNF587 ZNF697 ZSCAN21
Entrez ID		58524	386681
HPRD ID		16827	11194
Ensembl ID		ENSG00000064218	ENSG00000187766
Uniprot IDs		Q9NQL9	P60410
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Signal Transduction Regulation Of Intracellular Transport Regulation Of Signal Transduction Regulation Of Nucleocytoplasmic Transport Negative Regulation Of Viral Process Regulation Of Intracellular Protein Transport Regulation Of Signaling Negative Regulation Of Viral Release From Host Cell Negative Regulation Of Transferase Activity Positive Regulation Of Nucleocytoplasmic Transport Regulation Of Protein Transport Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of Cellular Localization Negative Regulation Of Viral Transcription Negative Regulation Of Cellular Metabolic Process Regulation Of Viral Release From Host Cell Regulation Of Establishment Of Protein Localization Regulation Of Protein Metabolic Process Regulation Of Viral Process Positive Regulation Of Intracellular Protein Transport Regulation Of Protein Import Into Nucleus Regulation Of Protein Localization Regulation Of Metabolic Process Positive Regulation Of Intracellular Signal Transduction Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Negative Regulation Of Wnt Signaling Pathway Regulation Of Protein Localization To Nucleus Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Negative Regulation Of Protein Kinase Activity Regulation Of I-kappaB Kinase/NF-kappaB Signaling Negative Regulation Of Kinase Activity Positive Regulation Of Intracellular Transport Regulation Of Transcription, DNA-templated I-kappaB Kinase/NF-kappaB Signaling Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Protein Ubiquitination Regulation Of Cellular Process Regulation Of RNA Metabolic Process Protein Modification By Small Protein Conjugation Regulation Of Protein Phosphorylation Regulation Of Viral Transcription Spermidine Acetylation Negative Regulation Of Interleukin-2 Secretion Catenin Import Into Nucleus Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Epithelial To Mesenchymal Transition Transcription, DNA-templated Negative Regulation Of RNA Biosynthetic Process Regulation Of Wnt Signaling Pathway	Keratinization RNA Biosynthetic Process Transcription, DNA-templated Gene Expression RNA Metabolic Process Pattern Specification Process Keratinocyte Differentiation Organ Development Epithelium Development Cellular Nitrogen Compound Metabolic Process Developmental Process Nucleobase-containing Compound Metabolic Process Nitrogen Compound Metabolic Process Multicellular Organismal Development Cellular Aromatic Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Epidermis Development Tissue Development Negative Regulation Of Glomerulus Development Negative Regulation Of Glomerular Mesangial Cell Proliferation Epidermal Cell Differentiation Macromolecule Biosynthetic Process Metanephric Mesenchyme Development Heterocycle Metabolic Process Negative Regulation Of Neurotrophin TRK Receptor Signaling Pathway Sperm Motility Negative Regulation Of Cell Proliferation Involved In Kidney Development Fertilization Biosynthetic Process Anterior/posterior Pattern Specification Anatomical Structure Development Epithelial Cell Differentiation Regulation Of Neurotrophin TRK Receptor Signaling Pathway Metanephric S-shaped Body Morphogenesis Single Fertilization System Development Branching Morphogenesis Of An Epithelial Tube Regulation Of Glomerular Mesangial Cell Proliferation Penetration Of Zona Pellucida S-shaped Body Morphogenesis Positive Regulation Of Immune Response To Tumor Cell Floor Plate Development Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Tube Development Skin Development Bud Elongation Involved In Lung Branching Morphogenesis Of A Branching Epithelium Negative Regulation Of Mesenchymal Cell Apoptotic Process Epithelial Tube Branching Involved In Lung Morphogenesis Morphogenesis Of A Branching Structure
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