KCNA4 and COXFA4L2

Number of citations: 0 (PubMedID 16169070)
Data Source: BioGRID (two hybrid), HPRD (two hybrid)

		KCNA4	COXFA4L2
Name		potassium voltage-gated channel subfamily A member 4	cytochrome c oxidase hypoxia associated subunit FA4L2
Structure		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Voltage-gated Potassium Channel Complex Membrane Axon Monoatomic Ion Channel Complex Cell Projection Axon Initial Segment Dendritic Spine	Mitochondrion Respiratory Chain Complex IV
	Molecular Function	Monoatomic Ion Channel Activity Voltage-gated Potassium Channel Activity Delayed Rectifier Potassium Channel Activity Potassium Channel Activity Protein Binding Potassium Ion Binding Voltage-gated Monoatomic Ion Channel Activity Involved In Regulation Of Presynaptic Membrane Potential	None
	Biological Process	Action Potential Monoatomic Ion Transport Potassium Ion Transport Monoatomic Ion Transmembrane Transport Protein Homooligomerization Transmembrane Transport Potassium Ion Transmembrane Transport Regulation Of Presynaptic Membrane Potential	None
Pathways		Voltage gated Potassium channels	None
Drugs		Enflurane Promethazine Miconazole Arginineamide Dalfampridine	NADH
GWAS		Adult body size ( 32376654 ) Diastolic blood pressure ( 27841878 ) Luteinizing hormone levels in polycystic ovary syndrome ( 26284813 ) Menarche (age at onset) ( 27182965 ) Polycystic ovary syndrome ( 26284813 ) Refractive error ( 32231278 ) Spherical equivalent or myopia (age of diagnosis) ( 29808027 ) Systolic blood pressure ( 27841878 )	No GWAS studies recorded
Interacting Genes		16 interacting genes: ACTN2 CASK COXFA4L2 DLG1 DLG2 DLG3 DLG4 DLGAP1 ERBIN KCNA2 LNX1 NEU1 PATJ SAT1 SNTA1 SNTG1	14 interacting genes: ANXA9 C6orf62 COMMD8 DYNLL1 EIF3C ERG28 KAT5 KCNA4 LUC7L2 NUFIP2 PRKN QTRT1 SLC35F6 UBR1
Entrez ID		3739	56901
HPRD ID		01444	14249
Ensembl ID		ENSG00000182255	ENSG00000185633
Uniprot IDs		P22459	Q9NRX3
PDB IDs		Not available	Not available
GO Terms Enriched among Interactors		Establishment Or Maintenance Of Apical/basal Cell Polarity Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Neuromuscular Junction Cell Junction Regulation Of Postsynaptic Membrane Neurotransmitter Receptor Levels Establishment Or Maintenance Of Cell Polarity Ionotropic Glutamate Receptor Binding Postsynaptic Density Membrane GMP Kinase Activity Receptor Localization To Synapse GDP Metabolic Process Receptor Clustering Juxtaparanode Region Of Axon Protein Localization To Synapse Glutamatergic Synapse Protein Localization To Cell Junction Kinase Binding GMP Metabolic Process Basolateral Plasma Membrane Syntrophin Complex Cell Adhesion Protein Localization To Membrane Chemical Synaptic Transmission Neuron Projection Trans-synaptic Signaling Synapse Synaptic Signaling Plasma Membrane Cell Communication Adherens Junction Anchoring Junction Regulation Of Membrane Potential Nucleoside Monophosphate Metabolic Process Postsynaptic Specialization Ribonucleoside Diphosphate Metabolic Process Voltage-gated Potassium Channel Complex PDZ Domain Binding Nucleoside Diphosphate Metabolic Process Cellular Response To Potassium Ion Postsynaptic Density Basement Membrane Dystrophin-associated Glycoprotein Complex Localization Within Membrane Neurotransmitter Receptor Localization To Postsynaptic Specialization Membrane Nervous System Development Response To Potassium Ion Cell-cell Signaling Bicellular Tight Junction Signaling Transmembrane Transporter Binding	None