KCNA4 and NDUFA4L2

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		KCNA4	NDUFA4L2
Gene Name		potassium channel, voltage gated shaker related subfamily A, member 4	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Voltage-gated Potassium Channel Complex Integral Component Of Membrane Axon
	Molecular Function	Voltage-gated Potassium Channel Activity Delayed Rectifier Potassium Channel Activity Protein Binding Potassium Ion Binding
	Biological Process	Potassium Ion Transport Synaptic Transmission Regulation Of Ion Transmembrane Transport Protein Homooligomerization Potassium Ion Transmembrane Transport
Pathways		Potassium Channels Voltage gated Potassium channels
Drugs			NADH
Diseases
GWAS
Protein-Protein Interactions		16 interactors: ACTN2 CASK DLG1 DLG2 DLG3 DLG4 DLGAP1 ERBB2IP INADL KCNA2 LNX1 NDUFA4L2 NEU1 SAT1 SNTA1 SNTG1	13 interactors: ANXA9 C14orf1 C6orf62 COMMD8 DYNLL1 EIF3C KAT5 KCNA4 LUC7L2 PARK2 QTRT1 SLC35F6 UBR1
Entrez ID		3739	56901
HPRD ID		01444	14249
Ensembl ID		ENSG00000182255	ENSG00000185633
Uniprot IDs		P22459	Q9NRX3
PDB IDs
Enriched GO Terms of Interacting Partners?		Receptor Localization To Synapse Nucleotide Phosphorylation Protein Localization To Synapse Synaptic Transmission Establishment Or Maintenance Of Apical/basal Cell Polarity Cell-cell Signaling Receptor Clustering Regulation Of Ion Transmembrane Transport Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Regulation Of Membrane Potential Nucleotide Metabolic Process Regulation Of Ion Transport Nucleobase-containing Small Molecule Metabolic Process Establishment Or Maintenance Of Cell Polarity Organophosphate Metabolic Process Protein Localization To Membrane Cell Communication Cortical Actin Cytoskeleton Organization Positive Regulation Of Potassium Ion Transport Cortical Cytoskeleton Organization Regulation Of Sodium Ion Transmembrane Transport Positive Regulation Of Ion Transport Cell Junction Assembly Small Molecule Metabolic Process Cell-cell Junction Organization Muscle Contraction Tight Junction Assembly Signaling Protein Homooligomerization Muscle System Process Cellular Component Assembly Negative Regulation Of Phosphatase Activity Regulation Of Vasoconstriction By Circulating Norepinephrine Regulation Of Potassium Ion Transport Regulation Of Sodium Ion Transport Negative Regulation Of Dephosphorylation Apical Junction Assembly Cellular Protein Localization Positive Regulation Of Ion Transmembrane Transport Optic Nerve Structural Organization Spermidine Acetylation Basal Protein Localization Action Potential Sensory Perception Of Pain Membrane Organization Axon Guidance Regulation Of Phosphatase Activity Putrescine Catabolic Process Protein Oligomerization Cellular Localization	Regulation Of Mitochondrion Organization Negative Regulation Of Mitochondrion Organization Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Positive Regulation Of Mitochondrion Organization Negative Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway Positive Regulation Of Mitochondrial Fusion Positive Regulation Of Protein Linear Polyubiquitination Cellular Response To Leucine Dopamine Uptake Involved In Synaptic Transmission Positive Regulation Of Oxidative Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Cellular Response To Dopamine Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Queuosine Biosynthetic Process Proteolysis Involved In Cellular Protein Catabolic Process Negative Regulation Of Oxidative Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Cellular Response To Manganese Ion Negative Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Protein K27-linked Ubiquitination Protein K29-linked Ubiquitination Negative Regulation Of Mitochondrial Fusion Cellular Protein Catabolic Process Synaptic Transmission Positive Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway Regulation Of Mitochondrial Fusion Protein Catabolic Process Ribonucleoprotein Complex Assembly Negative Regulation Of Glucokinase Activity Neuron Cellular Homeostasis Response To Leucine Positive Regulation Of Oxidative Stress-induced Cell Death Protein K6-linked Ubiquitination Negative Regulation Of Oxidative Stress-induced Neuron Death Positive Regulation Of Apoptotic Signaling Pathway Positive Regulation Of Mitochondrial Fission Regulation Of Mitochondrion Degradation Dopamine Transport Aggresome Assembly Regulation Of Mitochondrial Fission Neurotransmitter Uptake Norepinephrine Metabolic Process DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Transcription Of P21 Class Mediator DNA Damage Response, Signal Transduction Resulting In Transcription Negative Regulation Of Actin Filament Bundle Assembly Synaptic Transmission, Dopaminergic Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Apoptotic Signaling Pathway Proteasomal Protein Catabolic Process Cellular Macromolecule Catabolic Process
Tagcloud ?			apoeepsilon4 astrocyte astrocytes billion c3 capture carriers cd74 cingulate clarified clu coexpression contributions decades deficits differentially fastkd2 measureable microdissected pc posterior precuneus publicly reads resource storage transcriptome trmt61b weighted
Tagcloud (Difference) ?			apoeepsilon4 astrocyte astrocytes billion c3 capture carriers cd74 cingulate clarified clu coexpression contributions decades deficits differentially fastkd2 measureable microdissected pc posterior precuneus publicly reads resource storage transcriptome trmt61b weighted
Tagcloud (Intersection) ?