S100A7 and TGM2

Number of citations of the paper that reports this interaction (PMID 11258932)
15

Data Source:
HPRD (in vitro)

		S100A7	TGM2
Gene Name		S100 calcium binding protein A7	transglutaminase 2
Image
Gene Ontology Annotations	Cellular Component	Extracellular Region Nucleus Cytoplasm Endoplasmic Reticulum Cytosol Focal Adhesion Extracellular Vesicular Exosome	Mitochondrion Cytosol Plasma Membrane Focal Adhesion Extracellular Vesicular Exosome
	Molecular Function	Calcium Ion Binding Protein Binding Zinc Ion Binding RAGE Receptor Binding	Protein-glutamine Gamma-glutamyltransferase Activity Protein Binding GTP Binding Protein Domain Specific Binding Metal Ion Binding
	Biological Process	Response To Reactive Oxygen Species Angiogenesis Epidermis Development Positive Regulation Of T Cell Chemotaxis Keratinocyte Differentiation Response To Lipopolysaccharide Innate Immune Response Defense Response To Gram-negative Bacterium Sequestering Of Metal Ion Positive Regulation Of ERK1 And ERK2 Cascade Positive Regulation Of Granulocyte Chemotaxis Positive Regulation Of Monocyte Chemotaxis	Blood Vessel Remodeling Isopeptide Cross-linking Via N6-(L-isoglutamyl)-L-lysine Negative Regulation Of Endoplasmic Reticulum Calcium Ion Concentration Positive Regulation Of Apoptotic Process Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Apoptotic Cell Clearance Positive Regulation Of Cell Adhesion Positive Regulation Of Smooth Muscle Cell Proliferation Positive Regulation Of Inflammatory Response Protein Homooligomerization Positive Regulation Of Cytosolic Calcium Ion Concentration Involved In Phospholipase C-activating G-protein Coupled Signaling Pathway Positive Regulation Of Mitochondrial Calcium Ion Concentration Branching Involved In Salivary Gland Morphogenesis Salivary Gland Cavitation
Pathways
Drugs			Guanosine-5\'-Diphosphate
Diseases
GWAS
Protein-Protein Interactions		6 interactors: COPS5 EGFR FABP5 RANBP9 TGM2 UCHL5	55 interactors: A2M ABCA1 ACTB ADAR ALDOA ANKRD28 ANXA1 APP ATF4 BNIP3 C3 CASP3 COL4A3BP CSNK2A2 EIF5A FN1 FNTA GCGR GRN GSTP1 HIST1H2BG HIST2H2BE HNRNPF HNRNPUL1 HP HSPA1A HSPA1B HSPA8 HTT ITGB1 ITGB3 KPNA3 KPNA4 LTBP1 MAP3K12 PAK1 PLCD1 PPHLN1 RB1 RELA RHOA S100A7 SERPINF2 SERTAD1 SIPA1L2 SLC7A9 SMAD2 SMAD3 SPARC SUMO1 TAB2 TMEM176A TMSB4X TUBB ZNF512B
Entrez ID		6278	7052
HPRD ID		02645	01825
Ensembl ID		ENSG00000143556	ENSG00000198959
Uniprot IDs		P31151	B4DIT7 F5H6P0 P21980
PDB IDs		1PSR 2PSR 2WND 2WOR 2WOS 3PSR 4AQJ	1FAU 1KV3 2Q3Z 3LY6 3S3J 3S3P 3S3S
Enriched GO Terms of Interacting Partners?		Salivary Gland Morphogenesis Salivary Gland Development Positive Regulation Of Smooth Muscle Cell Proliferation Exocrine System Development Positive Regulation Of Inflammatory Response Alkanesulfonate Metabolic Process Regulation Of Smooth Muscle Cell Proliferation Protein Deubiquitination Protein Modification By Small Protein Removal Activation Of Phospholipase A2 Activity By Calcium-mediated Signaling Isopeptide Cross-linking Via N6-(L-isoglutamyl)-L-lysine Astrocyte Activation Gland Morphogenesis Activation Of Phospholipase A2 Activity Exosomal Secretion Positive Regulation Of Phospholipase A2 Activity Organ Morphogenesis Anatomical Structure Morphogenesis Response To Cobalamin Response To UV-A Salivary Gland Cavitation Response To Hydroxyisoflavone Epithelium Development Epidermis Development Positive Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Involved In G1/S Transition Of Mitotic Cell Cycle Positive Regulation Of Superoxide Anion Generation Anatomical Structure Development Regulation Of Inflammatory Response Positive Regulation Of Mitochondrial Calcium Ion Concentration Negative Regulation Of Endoplasmic Reticulum Calcium Ion Concentration Cullin Deneddylation Telencephalon Development Regulation Of Signal Transduction Positive Regulation Of Catenin Import Into Nucleus Protein Deneddylation Regulation Of Phospholipase A2 Activity Regulation Of Superoxide Anion Generation Developmental Process Regulation Of Signaling Magnesium Ion Homeostasis Regulation Of Protein Catabolic Process Axon Guidance Positive Regulation Of Cytosolic Calcium Ion Concentration Involved In Phospholipase C-activating G-protein Coupled Signaling Pathway Mitochondrial Calcium Ion Homeostasis Cellular Protein Modification Process Tube Morphogenesis Cellular Response To Estradiol Stimulus Forebrain Development Protein Insertion Into Membrane Astrocyte Development	Response To Stress Response To External Stimulus Response To Stimulus Secretion By Cell Establishment Of Localization In Cell Platelet Degranulation Secretion Regulation Of Cellular Protein Metabolic Process Regulation Of Protein Metabolic Process Cellular Localization Positive Regulation Of Metabolic Process Platelet Activation Regulation Of Cell Proliferation Response To Wounding Regulation Of Signal Transduction Response To Other Organism Positive Regulation Of Cellular Metabolic Process Wound Healing Response To Biotic Stimulus Immune System Process Response To Oxidative Stress Blood Coagulation Response To Organic Substance Hemostasis Regulation Of Cellular Process Regulation Of Signaling Regulation Of Cellular Component Organization Defense Response Regulation Of Phosphorus Metabolic Process Regulation Of Immune System Process Cellular Response To Stimulus Cell Activation Regulation Of Catalytic Activity Signal Transduction Signaling Exocytosis Regulation Of Body Fluid Levels Positive Regulation Of Protein Metabolic Process Cell Communication Negative Regulation Of Protein Metabolic Process Cellular Response To Organic Substance Positive Regulation Of Cellular Protein Metabolic Process Cell Surface Receptor Signaling Pathway Regulation Of Phosphorylation Regulation Of Metabolic Process Viral Process Viral Entry Into Host Cell Entry Into Host Cell Regulation Of Protein Phosphorylation Response To Abiotic Stimulus
Tagcloud ?		29b cdc42 conclusionsthe dataset decoy determining downregulates elaborated elusive inverted mark markb mcf7 methodswe mir modulations nude p85 psoriasin question represented resultsin reversing suppressing tcga transfecting upregulates verified	antral atresia atretic bga build categorized cattle cct2 cyp11a1 cyp19a1 dab2 dairy dsg2 e2f1 follicle follicles follicular granulosa hybridized microarrays offers oocyte originating phases plateau segregation steroidogenesis transcriptomic ultimately
Tagcloud (Difference) ?		29b cdc42 conclusionsthe dataset decoy determining downregulates elaborated elusive inverted mark markb mcf7 methodswe mir modulations nude p85 psoriasin question represented resultsin reversing suppressing tcga transfecting upregulates verified	antral atresia atretic bga build categorized cattle cct2 cyp11a1 cyp19a1 dab2 dairy dsg2 e2f1 follicle follicles follicular granulosa hybridized microarrays offers oocyte originating phases plateau segregation steroidogenesis transcriptomic ultimately
Tagcloud (Intersection) ?