S100A7 and RANBP9

Number of citations of the paper that reports this interaction (PubMedID 12421467)
21

Data Source:
HPRD (in vivo, two hybrid)

		S100A7	RANBP9
Description		S100 calcium binding protein A7	RAN binding protein 9
Image
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Nucleus Cytoplasm Endoplasmic Reticulum Cytosol Focal Adhesion Extracellular Matrix Azurophil Granule Lumen	Ubiquitin Ligase Complex Nucleus Nucleoplasm Cytoplasm Cytosol Microtubule Associated Complex Plasma Membrane Membrane Nuclear Body
	Molecular Function	Calcium Ion Binding Protein Binding Zinc Ion Binding Metal Ion Binding Transition Metal Ion Binding Calcium-dependent Protein Binding RAGE Receptor Binding Zinc Ion Sequestering Activity	Protein Binding Enzyme Binding Small GTPase Binding
	Biological Process	Response To Reactive Oxygen Species Angiogenesis Epidermis Development Positive Regulation Of T Cell Chemotaxis Keratinocyte Differentiation Response To Lipopolysaccharide Endothelial Cell Migration Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Positive Regulation Of ERK1 And ERK2 Cascade Positive Regulation Of Granulocyte Chemotaxis Positive Regulation Of Monocyte Chemotaxis	Cytoskeleton Organization Microtubule Nucleation Protein-containing Complex Assembly Negative Regulation Of ERK1 And ERK2 Cascade Positive Regulation Of Amyloid Precursor Protein Catabolic Process
Pathways		Neutrophil degranulation Metal sequestration by antimicrobial proteins	L1CAM interactions RAF/MAP kinase cascade MET activates RAS signaling Regulation of pyruvate metabolism
Drugs		Ibuprofen Zinc 8-anilinonaphthalene-1-sulfonic acid Dexibuprofen Zinc acetate Zinc chloride Zinc sulfate, unspecified form
Diseases
GWAS		Blood protein levels ( 30072576)	Breast cancer ( 23535729 29059683)
Interacting Genes		9 interacting genes: CLVS2 COPS5 EGFR FABP5 RANBP9 S100A7L2 TGM2 UCHL5 WEE2-AS1	67 interacting genes: ADAP1 ADAP2 APC AR ATM AXL BACE1 BRCA1 BTG3 CACNA1G CALB1 CBR1 CBR3 CBS CCND1 CDK11B CDKN1A CFAP298 CLEC7A DDX4 DISC1 DYRK1B ENTPD1 ESR1 EXOC2 FMR1 GATD3 GID8 GRIK1 HIPK2 HMBS HNF4G ITGAL ITGB2 L1CAM LCOR LMNA MAPK6 MET MORC3 MPHOSPH8 NCOA6 NCOR2 NSRP1 PPARD PPARG PPP1CA PRKACA RAF1 RAN S100A7 SMAD2 SMAD3 SMAD9 SOD1 SOS1 SPOP SPP1 TFRC THRA THRB TP53 TP73 UCHL1 USP11 WNK1 ZBED1
Entrez ID		6278	10048
HPRD ID		02645	04835
Ensembl ID		ENSG00000143556	ENSG00000010017
Uniprot IDs		P31151	Q96S59
PDB IDs		1PSR 2PSR 2WND 2WOR 2WOS 3PSR 4AQJ	5JI7 5JI9 5JIU 7NSC
Enriched GO Terms of Interacting Partners?		Multivesicular Body, Internal Vesicle Lumen Peptide Dopaminyltransferase Activity Histone Serotonyltransferase Activity Peptide Histaminyltransferase Activity Protein-glutamine Glutaminase Activity Peptide Noradrenalinyltransferase Activity Peptidase Activity Peptide Serotonyltransferase Activity Histone Dopaminyltransferase Activity Lysosome Organization	Developmental Process Cellular Developmental Process Animal Organ Development Regulation Of Programmed Cell Death Nucleoplasm Protein-containing Complex Binding Intracellular Signal Transduction Regulation Of Cell Communication Regulation Of Signaling Nuclear Receptor Activity Enzyme Binding Positive Regulation Of Metabolic Process Positive Regulation Of Cell Communication Positive Regulation Of Signaling Regulation Of Biological Quality Regulation Of Apoptotic Process Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Macromolecule Metabolic Process Positive Regulation Of Biosynthetic Process Regulation Of Metabolic Process Positive Regulation Of Signal Transduction Protein Kinase Binding Regulation Of MiRNA Transcription Regulation Of Gene Expression Regulation Of Multicellular Organismal Process Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Molecular Condensate Scaffold Activity Cell Surface Receptor Signaling Pathway Transcription Coactivator Binding Regulation Of Intracellular Signal Transduction Regulation Of Macromolecule Biosynthetic Process Regulation Of MiRNA Metabolic Process Negative Regulation Of MiRNA Transcription Regulation Of Signal Transduction Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Primary Metabolic Process Signal Transduction Positive Regulation Of Macromolecule Metabolic Process Response To Stress Nucleus Positive Regulation Of RNA Metabolic Process Positive Regulation Of Reactive Oxygen Species Metabolic Process Negative Regulation Of Programmed Cell Death Ubiquitin Protein Ligase Binding Chromatin Binding Regulation Of Growth Apoptotic Signaling Pathway
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