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TRPV4 and PACSIN3
Number of citations of the paper that reports this interaction (PMID
16627472
)
34
Data Source:
HPRD
(in vivo, two hybrid, in vitro)
TRPV4
PACSIN3
Gene Name
transient receptor potential cation channel, subfamily V, member 4
protein kinase C and casein kinase substrate in neurons 3
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Cytoplasmic Microtubule
Plasma Membrane
Adherens Junction
Focal Adhesion
Cilium
Cell Surface
Integral Component Of Membrane
Lamellipodium
Filopodium
Growth Cone
Cortical Actin Cytoskeleton
Cytoplasmic Vesicle
Ruffle Membrane
Nucleoplasm
Cytoplasm
Endosome
Plasma Membrane
Membrane
Membrane-bounded Vesicle
Extracellular Vesicular Exosome
Molecular Function
Actin Binding
Osmosensor Activity
Protein Kinase C Binding
Cation Channel Activity
Calcium Channel Activity
Calmodulin Binding
ATP Binding
Microtubule Binding
Protein Kinase Binding
SH2 Domain Binding
Alpha-tubulin Binding
Beta-tubulin Binding
Actin Filament Binding
Protein Binding
Phospholipid Binding
Cytoskeletal Protein Binding
Lipid Binding
Calcium Channel Inhibitor Activity
Biological Process
Calcium Ion Transport
Cellular Calcium Ion Homeostasis
Cell Volume Homeostasis
Actin Filament Organization
Cell-cell Junction Assembly
Positive Regulation Of Cytosolic Calcium Ion Concentration
Osmosensory Signaling Pathway
Response To Mechanical Stimulus
Negative Regulation Of Neuron Projection Development
Vasopressin Secretion
Positive Regulation Of Microtubule Depolymerization
Actin Cytoskeleton Reorganization
Ion Transmembrane Transport
Cellular Response To Heat
Hyperosmotic Salinity Response
Cortical Microtubule Organization
Microtubule Polymerization
Regulation Of Response To Osmotic Stress
Transmembrane Transport
Calcium Ion Import
Calcium Ion Transmembrane Transport
Cellular Response To Osmotic Stress
Cellular Hypotonic Response
Endocytosis
Cytoskeleton Organization
Regulation Of Endocytosis
Negative Regulation Of Endocytosis
Positive Regulation Of Membrane Protein Ectodomain Proteolysis
Negative Regulation Of Calcium Ion Transport
Membrane Tubulation
Pathways
Ion channel transport
TRP channels
Stimuli-sensing channels
Drugs
Diseases
GWAS
Protein-Protein Interactions
14 interactors:
CALM1
FYN
HCK
ITCH
KRIT1
LCK
LYN
MAP7
OS9
PACSIN1
PACSIN2
PACSIN3
SRC
YES1
18 interactors:
ADAM12
ADAM15
ASAP1
ASAP2
DNM1
ITSN1
LGALS13
PACSIN1
PACSIN2
PAK2
RAF1
SOS1
SOS2
SPRY2
SYNJ1
TERF2IP
TRPV4
WASL
Entrez ID
59341
29763
HPRD ID
05667
05937
Ensembl ID
ENSG00000111199
ENSG00000165912
Uniprot IDs
Q9HBA0
Q9UKS6
PDB IDs
4DX1
4DX2
Enriched GO Terms of Interacting Partners
?
Peptidyl-tyrosine Autophosphorylation
Immune Response-regulating Signaling Pathway
Fc Receptor Signaling Pathway
T Cell Costimulation
Immune Response-regulating Cell Surface Receptor Signaling Pathway
Endocytosis
Protein Autophosphorylation
Leukocyte Migration
Innate Immune Response
Peptidyl-tyrosine Phosphorylation
Immune Response-activating Cell Surface Receptor Signaling Pathway
Regulation Of Immune Response
Regulation Of T Cell Activation
Cellular Response To Peptide Hormone Stimulus
Cellular Response To Peptide
Vesicle-mediated Transport
Membrane Tubulation
Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis
Fc Receptor Mediated Stimulatory Signaling Pathway
Fc-gamma Receptor Signaling Pathway
Cellular Response To Platelet-derived Growth Factor Stimulus
Positive Regulation Of Immune Response
Response To Platelet-derived Growth Factor
Regulation Of Vesicle-mediated Transport
Regulation Of Cell-cell Adhesion
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Regulation Of Endocytosis
Regulation Of Lymphocyte Activation
Platelet Activation
Blood Coagulation
Hemostasis
Positive Regulation Of T Cell Activation
Positive Regulation Of Homotypic Cell-cell Adhesion
Response To Peptide Hormone
Regulation Of Defense Response To Virus
Cellular Response To Organonitrogen Compound
Regulation Of Cell Activation
Response To Organonitrogen Compound
Response To Peptide
Immune Response
Regulation Of Immune System Process
Positive Regulation Of Cell-cell Adhesion
Defense Response
Ephrin Receptor Signaling Pathway
Phagocytosis
Enzyme Linked Receptor Protein Signaling Pathway
Positive Regulation Of Immune System Process
Regulation Of Defense Response To Virus By Virus
Viral Process
Response To Hormone
Cell Morphogenesis
Cell Projection Morphogenesis
Cell Part Morphogenesis
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Anatomical Structure Morphogenesis
Cell Projection Organization
Enzyme Linked Receptor Protein Signaling Pathway
Axon Guidance
Neuron Projection Morphogenesis
Cell Morphogenesis Involved In Differentiation
Neuron Projection Development
Axonogenesis
Axon Development
Cell Morphogenesis Involved In Neuron Differentiation
Chemotaxis
Neuron Development
Regulation Of Ras Protein Signal Transduction
Anatomical Structure Development
Cell Differentiation
Generation Of Neurons
Regulation Of Small GTPase Mediated Signal Transduction
Neuron Differentiation
Neurogenesis
Developmental Process
Regulation Of Ras GTPase Activity
Synaptic Vesicle Endocytosis
Cell Development
Synaptic Vesicle Recycling
Establishment Of Organelle Localization
Endocytosis
Epidermal Growth Factor Receptor Signaling Pathway
ERBB Signaling Pathway
Positive Regulation Of Catalytic Activity
Regulation Of Endocytosis
Organelle Localization
Establishment Of Vesicle Localization
Nervous System Development
Regulation Of GTPase Activity
Vesicle Localization
Neurotrophin TRK Receptor Signaling Pathway
Signaling
Regulation Of Intracellular Signal Transduction
Positive Regulation Of Intracellular Signal Transduction
Regulation Of Catalytic Activity
Locomotion
Regulation Of Signaling
Neurotrophin Signaling Pathway
Positive Regulation Of Signal Transduction
Cell Communication
Cell Surface Receptor Signaling Pathway
Tagcloud
?
afferent
afferents
airway
airways
ankyrin
antitussives
arachidonic
channels
circumstances
cough
dangerous
diseased
gathered
harmful
impacting
initiates
lives
melastatin
nerves
osmolarity
reflex
trpa
trpm
uncover
unmet
vagal
vanilloid
Tagcloud (Difference)
?
afferent
afferents
airway
airways
ankyrin
antitussives
arachidonic
channels
circumstances
cough
dangerous
diseased
gathered
harmful
impacting
initiates
lives
melastatin
nerves
osmolarity
reflex
trpa
trpm
uncover
unmet
vagal
vanilloid
Tagcloud (Intersection)
?