LMCD1

Gene Name		LIM and cysteine-rich domains 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Space Nucleus Cytoplasm Extracellular Matrix
	Molecular Function	Transcription Corepressor Activity Zinc Ion Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated Regulation Of Cardiac Muscle Hypertrophy Positive Regulation Of Calcineurin-NFAT Signaling Cascade
Pathways
Drugs
Diseases
GWAS
Protein-protein Interactions		7 interactors: APP FBXO25 IKBKG NKX3-1 PRKAG3 TRIM55 TRIM63
Entrez ID		29995
HPRD ID		06891
Ensembl ID		ENSG00000071282
Uniprot IDs		B4DEY6 B4DG80 B7Z6R5 F5GX84 Q9NZU5
PDB IDs
Enriched GO Terms of Interacting Partners?		Intracellular Receptor Signaling Pathway Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Response To Interleukin-1 Cellular Response To Hormone Stimulus Positive Regulation Of Mitotic Cell Cycle Synaptic Growth At Neuromuscular Junction Positive Regulation Of Androgen Secretion Signal Transduction Cell Cycle Arrest Regulation Of Protein Binding Positive Regulation Of Peptidase Activity Regulation Of Intrinsic Apoptotic Signaling Pathway Collateral Sprouting In Absence Of Injury Negative Regulation Of Estrogen Receptor Binding Regulation Of Protein Kinase Activity Signaling Cell Communication Response To Electrical Stimulus Involved In Regulation Of Muscle Adaptation Regulation Of Kinase Activity Cellular Response To Steroid Hormone Stimulus Collateral Sprouting Axon Midline Choice Point Recognition Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Skeletal Muscle Atrophy Regulation Of Cell Cycle Axon Choice Point Recognition Striated Muscle Atrophy Response To Hormone Apoptotic Process Negative Regulation Of Receptor Binding Muscle Atrophy Programmed Cell Death Regulation Of Binding Negative Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway Positive Regulation Of Transcription From RNA Polymerase II Promoter Cellular Response To Stimulus Cell Death Death Neuron Remodeling Skeletal Muscle Adaptation Regulation Of Protein Phosphorylation Positive Regulation Of Cell Cycle Response To Abiotic Stimulus Dorsal Aorta Development Positive Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Proteolysis Epithelial Cell Proliferation Involved In Salivary Gland Morphogenesis Negative Regulation Of Epithelial Cell Proliferation Involved In Prostate Gland Development Positive Regulation Of Protein Metabolic Process Mitotic Cell Cycle Arrest
Tagcloud ?		anf antihypertrophic blunted calcineurin cardiomyocyte cardiomyocytes cardiomyopathic causal constitutionally contractile crossed disc dyxin exacerbated hypertrophic hypertrophy likewise lim mechanistically nrcm nrcms pe phenylephrine potently rcan1 sarcomeric stretch stretched upregulated