RABGGTB and WDR4

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		RABGGTB	WDR4
Gene Name		Rab geranylgeranyltransferase, beta subunit	WD repeat domain 4
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Rab-protein Geranylgeranyltransferase Complex	Nucleus Nucleoplasm Cytoplasm
	Molecular Function	Rab Geranylgeranyltransferase Activity Protein Binding Zinc Ion Binding Rab GTPase Binding	Protein Binding TRNA (guanine-N7-)-methyltransferase Activity
	Biological Process	Cellular Protein Modification Process Visual Perception Protein Geranylgeranylation	TRNA Modification TRNA Methylation RNA (guanine-N7)-methylation
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		16 interactors: ALAS2 ARAF B4GALT7 CHML FAM19A1 PTP4A2 RAB11A RAB1A RAB27A RAB37 RAB3A RAB5A RAB6A RAB7A TMEM25 WDR4	5 interactors: FAM118A METTL1 RABGGTB TERF1 TERF2
Entrez ID		5876	10785
HPRD ID		01532	09330
Ensembl ID		ENSG00000137955	ENSG00000160193
Uniprot IDs		A8KAJ2 P53611 Q6IB63	P57081
PDB IDs
Enriched GO Terms of Interacting Partners?		Rab Protein Signal Transduction Ras Protein Signal Transduction Intracellular Protein Transport Small GTPase Mediated Signal Transduction Cellular Protein Localization Protein Transport Establishment Of Protein Localization Regulation Of Exocytosis Intracellular Transport Regulation Of Vesicle-mediated Transport Positive Regulation Of Exocytosis Establishment Of Vesicle Localization Vesicle Localization Intracellular Signal Transduction Protein Localization Membrane Docking Establishment Of Localization In Cell Multivesicular Body Organization Vesicle-mediated Transport Protein Secretion Melanosome Transport Pigment Granule Transport Establishment Of Organelle Localization Establishment Of Melanosome Localization Regulation Of Endosome Size Melanosome Localization Cellular Localization Exosomal Secretion Organelle Localization Regulation Of Neuronal Synaptic Plasticity Cellular Pigmentation Endosomal Transport Vesicle Docking Involved In Exocytosis Secretion By Cell Vesicle Docking Secretion Regulation Of Secretion Positive Regulation Of Secretion Synaptic Vesicle Transport Cytoplasmic Transport Exocytosis Pigmentation Positive Regulation Of Regulated Secretory Pathway Early Endosome To Late Endosome Transport Endomembrane System Organization Regulation Of Synaptic Plasticity Regulation Of Long-term Neuronal Synaptic Plasticity Endosome Organization Regulation Of Synaptic Vesicle Exocytosis Synaptic Vesicle Recycling	Negative Regulation Of Telomere Maintenance Via Semi-conservative Replication Telomeric Loop Formation Age-dependent Telomere Shortening Telomere Maintenance Via Telomere Shortening Replicative Cell Aging Telomere Maintenance Via Telomerase Negative Regulation Of Telomere Maintenance Regulation Of Nuclear Cell Cycle DNA Replication Regulation Of Telomere Maintenance RNA-dependent DNA Replication Telomere Maintenance Via Telomere Lengthening Negative Regulation Of DNA Replication Cell Aging Telomere Maintenance Negative Regulation Of Chromosome Organization Negative Regulation Of DNA Metabolic Process Regulation Of DNA Replication Regulation Of Chromosome Organization RNA (guanine-N7)-methylation Protection From Non-homologous End Joining At Telomere Telomere Capping DNA Replication Negative Regulation Of Telomere Maintenance Via Telomerase Protein Localization To Chromosome, Telomeric Region Protein Geranylgeranylation Aging Negative Regulation Of Telomerase Activity Positive Regulation Of Telomere Maintenance Positive Regulation Of Organelle Organization Regulation Of Telomere Maintenance Via Telomerase Negative Regulation Of Cell Cycle Positive Regulation Of Microtubule Polymerization Regulation Of Cell Cycle Process Regulation Of Telomerase Activity Protein Prenylation Chromatin Modification TRNA Methylation Negative Regulation Of DNA Biosynthetic Process Regulation Of Microtubule Polymerization Protein Localization To Chromosome Cellular Senescence Chromatin Organization 7-methylguanosine RNA Capping Mitotic Spindle Assembly Checkpoint Spindle Assembly Checkpoint Mitotic Spindle Checkpoint Positive Regulation Of Mitotic Nuclear Division Negative Regulation Of Chromosome Segregation Regulation Of DNA Biosynthetic Process Spindle Checkpoint
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