WDR4 and FAM118A

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		WDR4	FAM118A
Gene Name		WD repeat domain 4	family with sequence similarity 118, member A
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm	Integral Component Of Membrane
	Molecular Function	Protein Binding TRNA (guanine-N7-)-methyltransferase Activity
	Biological Process	TRNA Modification TRNA Methylation RNA (guanine-N7)-methylation
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		5 interactors: FAM118A METTL1 RABGGTB TERF1 TERF2	9 interactors: AIDA ATOX1 FAM118B GLRX3 LNX1 MOB1A MOB3C SDCBP WDR4
Entrez ID		10785	55007
HPRD ID		09330	07936
Ensembl ID		ENSG00000160193	ENSG00000100376
Uniprot IDs		P57081	Q9NWS6
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Telomere Maintenance Via Semi-conservative Replication Telomeric Loop Formation Age-dependent Telomere Shortening Telomere Maintenance Via Telomere Shortening Replicative Cell Aging Telomere Maintenance Via Telomerase Negative Regulation Of Telomere Maintenance Regulation Of Nuclear Cell Cycle DNA Replication Regulation Of Telomere Maintenance RNA-dependent DNA Replication Telomere Maintenance Via Telomere Lengthening Negative Regulation Of DNA Replication Cell Aging Telomere Maintenance Negative Regulation Of Chromosome Organization Negative Regulation Of DNA Metabolic Process Regulation Of DNA Replication Regulation Of Chromosome Organization RNA (guanine-N7)-methylation Protection From Non-homologous End Joining At Telomere Telomere Capping DNA Replication Negative Regulation Of Telomere Maintenance Via Telomerase Protein Localization To Chromosome, Telomeric Region Protein Geranylgeranylation Aging Negative Regulation Of Telomerase Activity Positive Regulation Of Telomere Maintenance Positive Regulation Of Organelle Organization Regulation Of Telomere Maintenance Via Telomerase Negative Regulation Of Cell Cycle Positive Regulation Of Microtubule Polymerization Regulation Of Cell Cycle Process Regulation Of Telomerase Activity Protein Prenylation Chromatin Modification TRNA Methylation Negative Regulation Of DNA Biosynthetic Process Regulation Of Microtubule Polymerization Protein Localization To Chromosome Cellular Senescence Chromatin Organization 7-methylguanosine RNA Capping Mitotic Spindle Assembly Checkpoint Spindle Assembly Checkpoint Mitotic Spindle Checkpoint Positive Regulation Of Mitotic Nuclear Division Negative Regulation Of Chromosome Segregation Regulation Of DNA Biosynthetic Process Spindle Checkpoint	Intracellular Copper Ion Transport Regulation Of JNK Cascade Positive Regulation Of Extracellular Vesicular Exosome Assembly Regulation Of Stress-activated MAPK Cascade RNA (guanine-N7)-methylation Regulation Of Extracellular Vesicular Exosome Assembly
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