TFRC and ACAP1

Number of citations of the paper that reports this interaction (PMID 15525538)
20

Data Source:
HPRD (in vivo, in vitro)

		TFRC	ACAP1
Gene Name		transferrin receptor	ArfGAP with coiled-coil, ankyrin repeat and PH domains 1
Image
Gene Ontology Annotations	Cellular Component	Extracellular Region Extracellular Space Endosome Plasma Membrane Integral Component Of Plasma Membrane Coated Pit External Side Of Plasma Membrane Cell Surface Membrane Cytoplasmic Membrane-bounded Vesicle Vesicle Melanosome Intracellular Membrane-bounded Organelle Perinuclear Region Of Cytoplasm Recycling Endosome Extracellular Vesicular Exosome Blood Microparticle	Membrane Recycling Endosome Membrane
	Molecular Function	Double-stranded RNA Binding Transferrin Receptor Activity Protein Binding Identical Protein Binding Poly(A) RNA Binding	ARF GTPase Activator Activity Zinc Ion Binding
	Biological Process	Regulation Of Cell Growth Cellular Iron Ion Homeostasis Receptor-mediated Endocytosis Viral Process Osteoclast Differentiation Transferrin Transport Cellular Response To Drug Regulation Of Cell Proliferation Positive Regulation Of Bone Resorption Transmembrane Transport Iron Ion Import	Protein Transport Regulation Of ARF GTPase Activity Positive Regulation Of GTPase Activity
Pathways		Iron uptake and transport Golgi Associated Vesicle Biogenesis Transferrin endocytosis and recycling trans-Golgi Network Vesicle Budding Clathrin derived vesicle budding
Drugs
Diseases
GWAS		Mean corpuscular hemoglobin ( 20139978 19862010) Mean corpuscular volume ( 20139978 19862010) Pancreatic cancer ( 22158540) Red blood cell traits ( 23222517)
Protein-Protein Interactions		11 interactors: ACAP1 B4GALT1 CD247 CD4 GABARAP HFE RAB5B RAB8A RANBP9 SGTA TF	5 interactors: AKT1 IFFO1 ITGB1 TFRC VAMP3
Entrez ID		7037	9744
HPRD ID		01812	08474
Ensembl ID		ENSG00000072274	ENSG00000072818
Uniprot IDs		A8K6Q8 P02786	Q15027
PDB IDs		1CX8 1DE4 1SUV 2NSU 3KAS 3S9L 3S9M 3S9N	3JUE 3T9K 4F1P
Enriched GO Terms of Interacting Partners?		Protein Localization Protein Transport Establishment Of Protein Localization Regulation Of Defense Response To Virus By Virus Cellular Protein Localization Cellular Localization Transport Rab Protein Signal Transduction Cellular Response To Iron Ion Starvation Induction By Virus Of Host Cell-cell Fusion Protein Palmitoleylation T Cell Costimulation Intracellular Protein Transport Regulation Of Vesicle-mediated Transport Iron Ion Transport Regulation Of Defense Response To Virus Cellular Iron Ion Homeostasis T Cell Receptor Signaling Pathway Establishment Of Localization In Cell Iron Ion Homeostasis Lactose Biosynthetic Process Golgi Vesicle Fusion To Target Membrane Membrane Fusion Viral Process Immune System Process Response To Stimulus Antigen Receptor-mediated Signaling Pathway Cellular Response To Starvation Transition Metal Ion Homeostasis Response To Stress Regulation Of Exocytosis Disaccharide Metabolic Process Positive Regulation Of Immune Response Cellular Response To Nutrient Levels Response To Starvation Iron Ion Import Into Cell Vesicle-mediated Transport Penetration Of Zona Pellucida Positive Regulation Of Epithelial Cell Proliferation Involved In Wound Healing Plasma Membrane To Endosome Transport Intracellular Transport Positive Regulation Of Apoptotic Process Involved In Mammary Gland Involution Positive Regulation Of T Cell Activation Cellular Response To Extracellular Stimulus Positive Regulation Of Homotypic Cell-cell Adhesion Ras Protein Signal Transduction Multicellular Organismal Homeostasis Regulation Of Acrosome Reaction Positive Regulation Of Cell-cell Adhesion Cell Communication	Positive Regulation Of Establishment Of Protein Localization To Plasma Membrane Positive Regulation Of Protein Localization To Plasma Membrane Protein Transport Establishment Of Protein Localization Regulation Of Establishment Of Protein Localization To Plasma Membrane Regulation Of Protein Localization To Plasma Membrane Cellular Response To Mechanical Stimulus Protein Localization Maternal Process Involved In Female Pregnancy Glycogen Cell Differentiation Involved In Embryonic Placenta Development Membrane Organization Chemical Homeostasis Intracellular Protein Transport G1/S Transition Of Mitotic Cell Cycle Regulation Of Cellular Localization Cell-substrate Adhesion Cell Differentiation Response To Mechanical Stimulus Regulation Of Collagen Catabolic Process Plasma Membrane Organization Striated Muscle Cell Differentiation Female Pregnancy Calcium-independent Cell-matrix Adhesion Negative Regulation Of Plasma Membrane Long-chain Fatty Acid Transport Negative Regulation Of Fatty Acid Beta-oxidation Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Cellular Protein Localization Homeostatic Process Formation Of Radial Glial Scaffolds Response To UV-A Intracellular Transport Muscle Cell Differentiation Activation-induced Cell Death Of T Cells Positive Regulation Of Cell Migration Positive Regulation Of Cell Motility Leukocyte Differentiation Response To Light Stimulus Positive Regulation Of Cellular Component Movement Cell-cell Adhesion Mediated By Integrin Positive Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Involved In G1/S Transition Of Mitotic Cell Cycle Cellular Response To Granulocyte Macrophage Colony-stimulating Factor Stimulus Positive Regulation Of Locomotion Positive Regulation Of Cell Adhesion Regulation Of Neuron Projection Development SNARE Complex Assembly Regulation Of Cellular Amino Acid Metabolic Process Cellular Response To Organic Cyclic Compound Negative Regulation Of Transport Negative Regulation Of Fatty Acid Oxidation
Tagcloud ?		actb assessments bestkeeper brca1 colon ercc1 esophageal gapdh gastrointestinal genorm gusb normalized normfinder optimal personalized qrt ranking rectal reference represented rplpo rrm1 separately stmn1 taqman top2a tubb3 tyms vegfr2
Tagcloud (Difference) ?		actb assessments bestkeeper brca1 colon ercc1 esophageal gapdh gastrointestinal genorm gusb normalized normfinder optimal personalized qrt ranking rectal reference represented rplpo rrm1 separately stmn1 taqman top2a tubb3 tyms vegfr2
Tagcloud (Intersection) ?