RAB5A and AP1G2

Number of citations of the paper that reports this interaction (PMID 14665628)
21

Data Source:
BioGRID (two hybrid)

		RAB5A	AP1G2
Gene Name		RAB5A, member RAS oncogene family	adaptor-related protein complex 1, gamma 2 subunit
Image
Gene Ontology Annotations	Cellular Component	Ruffle Cytoplasm Endosome Early Endosome Cytosol Plasma Membrane Synaptic Vesicle Endosome Membrane Actin Cytoskeleton Endocytic Vesicle Axon Dendrite Somatodendritic Compartment Melanosome Zymogen Granule Membrane Neuronal Cell Body Terminal Bouton Protein Complex Axon Terminus Membrane Raft Phagocytic Vesicle Perinuclear Region Of Cytoplasm Recycling Endosome Extracellular Vesicular Exosome Cytoplasmic Side Of Early Endosome Membrane	Golgi Apparatus Golgi-associated Vesicle Endosome Membrane Membrane AP-1 Adaptor Complex Transport Vesicle
	Molecular Function	GTPase Activity Protein Binding GTP Binding GDP Binding GDP-dissociation Inhibitor Binding	Protein Binding Protein Transporter Activity
	Biological Process	Intracellular Protein Transport Endocytosis Blood Coagulation Positive Regulation Of Smooth Muscle Cell Migration Regulation Of Endocytosis Rab Protein Signal Transduction Synaptic Vesicle Recycling Early Endosome To Late Endosome Transport Positive Regulation Of Exocytosis Regulation Of Long-term Neuronal Synaptic Plasticity Positive Regulation Of Smooth Muscle Cell Proliferation Regulation Of Endosome Size Regulation Of Filopodium Assembly Receptor Internalization Involved In Canonical Wnt Signaling Pathway Regulation Of Synaptic Vesicle Exocytosis	Intracellular Protein Transport Viral Process Vesicle-mediated Transport
Pathways		Factors involved in megakaryocyte development and platelet production
Drugs
Diseases
GWAS			Sudden cardiac arrest ( 21658281)
Protein-Protein Interactions		41 interactors: AGTR1 ALS2CL ANKFY1 AP1G1 AP1G2 APPL1 APPL2 CHM CHML EEA1 GDI2 GGA1 GGA2 GGA3 GRIK4 ITSN1 NME2 OCRL RAB37 RAB7A RABAC1 RABEP1 RABEP2 RABGGTB RASA1 RBSN RIN1 RIN2 RIN3 RIT2 RUFY1 SDCBP SGSM3 STX4 SUN2 TBC1D15 TBC1D17 TBC1D3C TBC1D3F TSC2 USP6NL	12 interactors: AFTPH AP1S1 AP1S2 ATXN1L CENPK KDM1A NEDD4 PRMT6 RAB5A RABEP1 SYNRG XRN1
Entrez ID		5868	8906
HPRD ID		01542	04638
Ensembl ID		ENSG00000144566	ENSG00000213983
Uniprot IDs		B4DJA5 P20339	O75843 Q86V28
PDB IDs		1N6H 1N6I 1N6K 1N6L 1N6N 1N6O 1N6P 1N6R 1R2Q 1TU3 1TU4 3MJH	2E9G 2YMT 3ZHF 4BCX
Enriched GO Terms of Interacting Partners?		Positive Regulation Of GTPase Activity Regulation Of GTPase Activity Positive Regulation Of Hydrolase Activity Vesicle-mediated Transport Positive Regulation Of Catalytic Activity Positive Regulation Of Ras GTPase Activity Regulation Of Ras GTPase Activity Positive Regulation Of Rab GTPase Activity Regulation Of Rab GTPase Activity Regulation Of Rab Protein Signal Transduction Regulation Of Catalytic Activity Regulation Of Ras Protein Signal Transduction Positive Regulation Of Metabolic Process Regulation Of Small GTPase Mediated Signal Transduction Protein Transport Protein Localization Establishment Of Protein Localization Establishment Of Localization In Cell Intracellular Transport Transport Cellular Localization Endocytosis Intracellular Protein Transport Regulation Of Intracellular Signal Transduction Small GTPase Mediated Signal Transduction Endosomal Transport Regulation Of Signaling Regulation Of Signal Transduction Membrane Organization Cellular Protein Localization Protein Geranylgeranylation Regulation Of Vesicle-mediated Transport Regulation Of Metabolic Process Vesicle Fusion Membrane Fusion Positive Regulation Of Exocytosis Protein Prenylation Regulation Of Exocytosis Organelle Fusion Golgi To Lysosome Transport Vesicle Organization Intracellular Signal Transduction Ras Protein Signal Transduction Lysosomal Transport Golgi To Vacuole Transport Plasma Membrane To Endosome Transport Cytoplasmic Transport Signaling Positive Regulation Of Exosomal Secretion Regulation Of Exosomal Secretion	Protein Transport Establishment Of Protein Localization Endocytosis Protein Localization Vesicle-mediated Transport Intracellular Protein Transport Regulation Of Defense Response To Virus By Virus Viral Process Receptor Internalization Cellular Protein Localization Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To UV-induced DNA Damage Transmission Of Virus Regulation Of Primitive Erythrocyte Differentiation Development Involved In Symbiotic Interaction Intracellular Transport Positive Regulation Of Stem Cell Proliferation Receptor-mediated Endocytosis Receptor Metabolic Process Regulation Of Defense Response To Virus Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Post-Golgi Vesicle-mediated Transport Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II Histone H3-R2 Methylation Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II Regulation Of Stem Cell Proliferation Receptor Internalization Involved In Canonical Wnt Signaling Pathway Positive Regulation Of Hematopoietic Stem Cell Proliferation Regulation Of Endosome Size Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Establishment Of Localization In Cell Progesterone Receptor Signaling Pathway Chromatin Modification Regulation Of Immune System Process Negative Regulation Of Gene Expression Regulation Of Transcription From RNA Polymerase II Promoter In Response To UV-induced DNA Damage Nuclear MRNA Surveillance Regulation Of Hematopoietic Stem Cell Proliferation Negative Regulation Of Biosynthetic Process Negative Regulation Of Histone H3-K4 Methylation Histone H3-K9 Demethylation Histone H3-K4 Demethylation Glucocorticoid Receptor Signaling Pathway RNA Surveillance Cellular Localization Histone MRNA Catabolic Process Chromatin Organization Transport Positive Regulation Of Megakaryocyte Differentiation
Tagcloud ?		accelerated anchored apposing confer directionality effectors endomembrane endosomal enigmatic exactly golgi gtpases liposomes localize master membrane organelles rab2a rab7a rabs reconstitution representative reversible strictly strikingly tethering tethers thoroughly
Tagcloud (Difference) ?		accelerated anchored apposing confer directionality effectors endomembrane endosomal enigmatic exactly golgi gtpases liposomes localize master membrane organelles rab2a rab7a rabs reconstitution representative reversible strictly strikingly tethering tethers thoroughly
Tagcloud (Intersection) ?