RAB5A and RBSN

Number of citations of the paper that reports this interaction (PMID 11062261)
82

Data Source:
HPRD (in vitro)

		RAB5A	RBSN
Gene Name		RAB5A, member RAS oncogene family	rabenosyn, RAB effector
Image
Gene Ontology Annotations	Cellular Component	Ruffle Cytoplasm Endosome Early Endosome Cytosol Plasma Membrane Synaptic Vesicle Endosome Membrane Actin Cytoskeleton Endocytic Vesicle Axon Dendrite Somatodendritic Compartment Melanosome Zymogen Granule Membrane Neuronal Cell Body Terminal Bouton Protein Complex Axon Terminus Membrane Raft Phagocytic Vesicle Perinuclear Region Of Cytoplasm Recycling Endosome Extracellular Vesicular Exosome Cytoplasmic Side Of Early Endosome Membrane	Endosome Plasma Membrane Endosome Membrane Cytoplasmic Side Of Endosome Membrane Early Endosome Membrane Intracellular Membrane-bounded Organelle Extracellular Vesicular Exosome
	Molecular Function	GTPase Activity Protein Binding GTP Binding GDP Binding GDP-dissociation Inhibitor Binding	Protein Binding Zinc Ion Binding Rab GTPase Binding
	Biological Process	Intracellular Protein Transport Endocytosis Blood Coagulation Positive Regulation Of Smooth Muscle Cell Migration Regulation Of Endocytosis Rab Protein Signal Transduction Synaptic Vesicle Recycling Early Endosome To Late Endosome Transport Positive Regulation Of Exocytosis Regulation Of Long-term Neuronal Synaptic Plasticity Positive Regulation Of Smooth Muscle Cell Proliferation Regulation Of Endosome Size Regulation Of Filopodium Assembly Receptor Internalization Involved In Canonical Wnt Signaling Pathway Regulation Of Synaptic Vesicle Exocytosis	Vacuole Inheritance Golgi To Endosome Transport Golgi To Vacuole Transport Endocytosis Blood Coagulation Protein Transport Endosomal Transport Endosomal Vesicle Fusion Late Endosome To Vacuole Transport
Pathways		Factors involved in megakaryocyte development and platelet production	Factors involved in megakaryocyte development and platelet production
Drugs
Diseases
GWAS
Protein-Protein Interactions		41 interactors: AGTR1 ALS2CL ANKFY1 AP1G1 AP1G2 APPL1 APPL2 CHM CHML EEA1 GDI2 GGA1 GGA2 GGA3 GRIK4 ITSN1 NME2 OCRL RAB37 RAB7A RABAC1 RABEP1 RABEP2 RABGGTB RASA1 RBSN RIN1 RIN2 RIN3 RIT2 RUFY1 SDCBP SGSM3 STX4 SUN2 TBC1D15 TBC1D17 TBC1D3C TBC1D3F TSC2 USP6NL	13 interactors: DISC1 DTNBP1 EHD1 EHD2 EHD3 MAPK14 RAB14 RAB24 RAB2A RAB4A RAB5A RAB5C VPS45
Entrez ID		5868	64145
HPRD ID		01542	15732
Ensembl ID		ENSG00000144566	ENSG00000131381
Uniprot IDs		B4DJA5 P20339	Q9H1K0
PDB IDs		1N6H 1N6I 1N6K 1N6L 1N6N 1N6O 1N6P 1N6R 1R2Q 1TU3 1TU4 3MJH	1YZM 1Z0J 1Z0K
Enriched GO Terms of Interacting Partners?		Positive Regulation Of GTPase Activity Regulation Of GTPase Activity Positive Regulation Of Hydrolase Activity Vesicle-mediated Transport Positive Regulation Of Catalytic Activity Positive Regulation Of Ras GTPase Activity Regulation Of Ras GTPase Activity Positive Regulation Of Rab GTPase Activity Regulation Of Rab GTPase Activity Regulation Of Rab Protein Signal Transduction Regulation Of Catalytic Activity Regulation Of Ras Protein Signal Transduction Positive Regulation Of Metabolic Process Regulation Of Small GTPase Mediated Signal Transduction Protein Transport Protein Localization Establishment Of Protein Localization Establishment Of Localization In Cell Intracellular Transport Transport Cellular Localization Endocytosis Intracellular Protein Transport Regulation Of Intracellular Signal Transduction Small GTPase Mediated Signal Transduction Endosomal Transport Regulation Of Signaling Regulation Of Signal Transduction Membrane Organization Cellular Protein Localization Protein Geranylgeranylation Regulation Of Vesicle-mediated Transport Regulation Of Metabolic Process Vesicle Fusion Membrane Fusion Positive Regulation Of Exocytosis Protein Prenylation Regulation Of Exocytosis Organelle Fusion Golgi To Lysosome Transport Vesicle Organization Intracellular Signal Transduction Ras Protein Signal Transduction Lysosomal Transport Golgi To Vacuole Transport Plasma Membrane To Endosome Transport Cytoplasmic Transport Signaling Positive Regulation Of Exosomal Secretion Regulation Of Exosomal Secretion	Rab Protein Signal Transduction Cellular Protein Localization Intracellular Protein Transport Intracellular Transport Ras Protein Signal Transduction Cellular Localization Protein Localization Establishment Of Localization In Cell Protein Transport Endocytic Recycling Establishment Of Protein Localization Endosomal Transport Blood Coagulation Hemostasis Regulation Of Body Fluid Levels Wound Healing Small GTPase Mediated Signal Transduction Response To Wounding Positive Regulation Of Myoblast Fusion Positive Regulation Of Syncytium Formation By Plasma Membrane Fusion Regulation Of Myoblast Fusion Vesicle-mediated Transport Positive Regulation Of Myotube Differentiation Positive Regulation Of Endocytic Recycling Regulation Of Vesicle-mediated Transport Response To Stimulus Intracellular Signal Transduction Transport Regulation Of Endocytic Recycling Regulation Of Myotube Differentiation Positive Regulation Of Striated Muscle Cell Differentiation Regulation Of Cardiac Muscle Cell Membrane Potential Positive Regulation Of Muscle Cell Differentiation Regulation Of Striated Muscle Cell Differentiation Regulation Of Cellular Component Organization Positive Regulation Of Transport Membrane Organization Regulation Of Muscle Cell Differentiation Endomembrane System Organization Regulation Of Endocytosis Regulation Of Cellular Localization Protein Targeting To Plasma Membrane Positive Regulation Of Intracellular Transport Endocytosis Protein Homooligomerization P38MAPK Cascade Phagolysosome Assembly Involved In Apoptotic Cell Clearance Regulation Of Neurotransmitter Secretion Signaling Cell Communication
Tagcloud ?		accelerated anchored apposing confer directionality effectors endomembrane endosomal enigmatic exactly golgi gtpases liposomes localize master membrane organelles rab2a rab7a rabs reconstitution representative reversible strictly strikingly tethering tethers thoroughly
Tagcloud (Difference) ?		accelerated anchored apposing confer directionality effectors endomembrane endosomal enigmatic exactly golgi gtpases liposomes localize master membrane organelles rab2a rab7a rabs reconstitution representative reversible strictly strikingly tethering tethers thoroughly
Tagcloud (Intersection) ?