RAB5A and RAB37

Number of citations of the paper that reports this interaction (PMID 10722846)
12

Data Source:
HPRD (two hybrid)

		RAB5A	RAB37
Gene Name		RAB5A, member RAS oncogene family	RAB37, member RAS oncogene family
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Ruffle Cytoplasm Endosome Early Endosome Cytosol Plasma Membrane Synaptic Vesicle Endosome Membrane Actin Cytoskeleton Endocytic Vesicle Axon Dendrite Somatodendritic Compartment Melanosome Zymogen Granule Membrane Neuronal Cell Body Terminal Bouton Protein Complex Axon Terminus Membrane Raft Phagocytic Vesicle Perinuclear Region Of Cytoplasm Recycling Endosome Extracellular Vesicular Exosome Cytoplasmic Side Of Early Endosome Membrane	Endosome Endoplasmic Reticulum-Golgi Intermediate Compartment Plasma Membrane Secretory Granule Membrane
	Molecular Function	GTPase Activity Protein Binding GTP Binding GDP Binding GDP-dissociation Inhibitor Binding	GTPase Activity GTP Binding GDP Binding
	Biological Process	Intracellular Protein Transport Endocytosis Blood Coagulation Positive Regulation Of Smooth Muscle Cell Migration Regulation Of Endocytosis Rab Protein Signal Transduction Synaptic Vesicle Recycling Early Endosome To Late Endosome Transport Positive Regulation Of Exocytosis Regulation Of Long-term Neuronal Synaptic Plasticity Positive Regulation Of Smooth Muscle Cell Proliferation Regulation Of Endosome Size Regulation Of Filopodium Assembly Receptor Internalization Involved In Canonical Wnt Signaling Pathway Regulation Of Synaptic Vesicle Exocytosis	Intracellular Protein Transport Vesicle Docking Involved In Exocytosis Protein Secretion Regulation Of Exocytosis Rab Protein Signal Transduction Protein Localization To Plasma Membrane
Pathways		Factors involved in megakaryocyte development and platelet production
Drugs
Diseases
GWAS
Protein-Protein Interactions		41 interactors: AGTR1 ALS2CL ANKFY1 AP1G1 AP1G2 APPL1 APPL2 CHM CHML EEA1 GDI2 GGA1 GGA2 GGA3 GRIK4 ITSN1 NME2 OCRL RAB37 RAB7A RABAC1 RABEP1 RABEP2 RABGGTB RASA1 RBSN RIN1 RIN2 RIN3 RIT2 RUFY1 SDCBP SGSM3 STX4 SUN2 TBC1D15 TBC1D17 TBC1D3C TBC1D3F TSC2 USP6NL	5 interactors: EWSR1 MAL2 RAB5A RABGGTB RIMS1
Entrez ID		5868	326624
HPRD ID		01542	06702
Ensembl ID		ENSG00000144566	ENSG00000172794
Uniprot IDs		B4DJA5 P20339	B7Z3L0 Q96AX2
PDB IDs		1N6H 1N6I 1N6K 1N6L 1N6N 1N6O 1N6P 1N6R 1R2Q 1TU3 1TU4 3MJH
Enriched GO Terms of Interacting Partners?		Positive Regulation Of GTPase Activity Regulation Of GTPase Activity Positive Regulation Of Hydrolase Activity Vesicle-mediated Transport Positive Regulation Of Catalytic Activity Positive Regulation Of Ras GTPase Activity Regulation Of Ras GTPase Activity Positive Regulation Of Rab GTPase Activity Regulation Of Rab GTPase Activity Regulation Of Rab Protein Signal Transduction Regulation Of Catalytic Activity Regulation Of Ras Protein Signal Transduction Positive Regulation Of Metabolic Process Regulation Of Small GTPase Mediated Signal Transduction Protein Transport Protein Localization Establishment Of Protein Localization Establishment Of Localization In Cell Intracellular Transport Transport Cellular Localization Endocytosis Intracellular Protein Transport Regulation Of Intracellular Signal Transduction Small GTPase Mediated Signal Transduction Endosomal Transport Regulation Of Signaling Regulation Of Signal Transduction Membrane Organization Cellular Protein Localization Protein Geranylgeranylation Regulation Of Vesicle-mediated Transport Regulation Of Metabolic Process Vesicle Fusion Membrane Fusion Positive Regulation Of Exocytosis Protein Prenylation Regulation Of Exocytosis Organelle Fusion Golgi To Lysosome Transport Vesicle Organization Intracellular Signal Transduction Ras Protein Signal Transduction Lysosomal Transport Golgi To Vacuole Transport Plasma Membrane To Endosome Transport Cytoplasmic Transport Signaling Positive Regulation Of Exosomal Secretion Regulation Of Exosomal Secretion	Regulation Of Long-term Neuronal Synaptic Plasticity Regulation Of Neuronal Synaptic Plasticity Regulation Of Neurotransmitter Secretion Synaptic Vesicle Transport Regulation Of Synaptic Plasticity Visual Perception Sensory Perception Of Light Stimulus Establishment Of Vesicle Localization Vesicle Localization Regulation Of Endosome Size Receptor Internalization Involved In Canonical Wnt Signaling Pathway Positive Regulation Of Inhibitory Postsynaptic Membrane Potential Regulation Of Synaptic Transmission Protein Geranylgeranylation Establishment Of Organelle Localization Calcium Ion-dependent Exocytosis Of Neurotransmitter Organelle Localization Regulation Of Inhibitory Postsynaptic Membrane Potential Protein Prenylation Early Endosome To Late Endosome Transport Synaptic Transmission Glutamate Secretion Regulation Of Secretion Positive Regulation Of Smooth Muscle Cell Migration Positive Regulation Of Excitatory Postsynaptic Membrane Potential Regulation Of Synaptic Vesicle Exocytosis Membrane Hyperpolarization Synaptic Vesicle Recycling Sensory Perception Regulation Of Synaptic Vesicle Transport Positive Regulation Of Membrane Potential Regulation Of Smooth Muscle Cell Migration Receptor Internalization Calcium Ion-dependent Exocytosis Regulation Of Filopodium Assembly Cell-cell Signaling Intracellular Protein Transport Regulated Secretory Pathway Synaptic Vesicle Exocytosis Positive Regulation Of Smooth Muscle Cell Proliferation Rab Protein Signal Transduction Acid Secretion Positive Regulation Of Exocytosis Regulation Of Cellular Localization Regulation Of Excitatory Postsynaptic Membrane Potential Regulation Of Postsynaptic Membrane Potential Neurological System Process Receptor Metabolic Process Dicarboxylic Acid Transport Canonical Wnt Signaling Pathway
Tagcloud ?		accelerated anchored apposing confer directionality effectors endomembrane endosomal enigmatic exactly golgi gtpases liposomes localize master membrane organelles rab2a rab7a rabs reconstitution representative reversible strictly strikingly tethering tethers thoroughly	colocalized constitutively controlling elucidated gtpase healing immunocytochemical interacting interacts isoforms knockdown lc macrophages munc13 positively rab27b rab30 rab33a rab3b rab40c raw264 secretion sirna skin tnf upregulated vesicles wound
Tagcloud (Difference) ?		accelerated anchored apposing confer directionality effectors endomembrane endosomal enigmatic exactly golgi gtpases liposomes localize master membrane organelles rab2a rab7a rabs reconstitution representative reversible strictly strikingly tethering tethers thoroughly	colocalized constitutively controlling elucidated gtpase healing immunocytochemical interacting interacts isoforms knockdown lc macrophages munc13 positively rab27b rab30 rab33a rab3b rab40c raw264 secretion sirna skin tnf upregulated vesicles wound
Tagcloud (Intersection) ?