AP1G2 and RABEP1

Number of citations of the paper that reports this interaction (PMID 12505986)
40

Data Source:
HPRD (in vitro)

		AP1G2	RABEP1
Gene Name		adaptor-related protein complex 1, gamma 2 subunit	rabaptin, RAB GTPase binding effector protein 1
Image
Gene Ontology Annotations	Cellular Component	Golgi Apparatus Golgi-associated Vesicle Endosome Membrane Membrane AP-1 Adaptor Complex Transport Vesicle	Endosome Early Endosome Endocytic Vesicle Intracellular Membrane-bounded Organelle Recycling Endosome
	Molecular Function	Protein Binding Protein Transporter Activity	GTPase Activator Activity Protein Binding Growth Factor Activity Protein Homodimerization Activity
	Biological Process	Intracellular Protein Transport Viral Process Vesicle-mediated Transport	Endocytosis Apoptotic Process Protein Transport Positive Regulation Of GTPase Activity Membrane Fusion
Pathways
Drugs
Diseases
GWAS		Sudden cardiac arrest ( 21658281)
Protein-Protein Interactions		12 interactors: AFTPH AP1S1 AP1S2 ATXN1L CENPK KDM1A NEDD4 PRMT6 RAB5A RABEP1 SYNRG XRN1	22 interactors: AP1G1 AP1G2 ATXN7 CASP3 CCND1 GAP43 GGA1 GGA2 GGA3 HUNK ITSN1 ITSN2 RAB1A RAB33B RAB4A RAB5A RABGEF1 RGS17 TRIM26 TSC2 UBC YWHAG
Entrez ID		8906	9135
HPRD ID		04638	04684
Ensembl ID		ENSG00000213983	ENSG00000029725
Uniprot IDs		O75843 Q86V28	F5H355 Q15276
PDB IDs		2E9G 2YMT 3ZHF 4BCX	1P4U 1TU3 1X79
Enriched GO Terms of Interacting Partners?		Protein Transport Establishment Of Protein Localization Endocytosis Protein Localization Vesicle-mediated Transport Intracellular Protein Transport Regulation Of Defense Response To Virus By Virus Viral Process Receptor Internalization Cellular Protein Localization Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To UV-induced DNA Damage Transmission Of Virus Regulation Of Primitive Erythrocyte Differentiation Development Involved In Symbiotic Interaction Intracellular Transport Positive Regulation Of Stem Cell Proliferation Receptor-mediated Endocytosis Receptor Metabolic Process Regulation Of Defense Response To Virus Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Post-Golgi Vesicle-mediated Transport Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II Histone H3-R2 Methylation Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II Regulation Of Stem Cell Proliferation Receptor Internalization Involved In Canonical Wnt Signaling Pathway Positive Regulation Of Hematopoietic Stem Cell Proliferation Regulation Of Endosome Size Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Establishment Of Localization In Cell Progesterone Receptor Signaling Pathway Chromatin Modification Regulation Of Immune System Process Negative Regulation Of Gene Expression Regulation Of Transcription From RNA Polymerase II Promoter In Response To UV-induced DNA Damage Nuclear MRNA Surveillance Regulation Of Hematopoietic Stem Cell Proliferation Negative Regulation Of Biosynthetic Process Negative Regulation Of Histone H3-K4 Methylation Histone H3-K9 Demethylation Histone H3-K4 Demethylation Glucocorticoid Receptor Signaling Pathway RNA Surveillance Cellular Localization Histone MRNA Catabolic Process Chromatin Organization Transport Positive Regulation Of Megakaryocyte Differentiation	Intracellular Protein Transport Intracellular Transport Establishment Of Localization In Cell Cellular Protein Localization Protein Transport Vesicle-mediated Transport Establishment Of Protein Localization Cellular Localization Protein Localization Transport Rab Protein Signal Transduction Regulation Of Vesicle-mediated Transport Membrane Organization Positive Regulation Of Metabolic Process Regulation Of Exocytosis Regulation Of Phosphorylation Intracellular Signal Transduction Endocytosis Regulation Of Endocytosis Negative Regulation Of Phosphorylation Regulation Of Phosphorus Metabolic Process Positive Regulation Of Catalytic Activity Neurotrophin TRK Receptor Signaling Pathway Ras Protein Signal Transduction Neurotrophin Signaling Pathway Regulation Of Protein Metabolic Process Regulation Of Catalytic Activity Negative Regulation Of Transferase Activity Signal Transduction Negative Regulation Of Protein Phosphorylation Regulation Of Signaling Regulation Of Cellular Component Organization Small GTPase Mediated Signal Transduction Virion Assembly Positive Regulation Of Hydrolase Activity Apoptotic Signaling Pathway Negative Regulation Of Protein Serine/threonine Kinase Activity Regulation Of Protein Phosphorylation Negative Regulation Of Signal Transduction Cytoplasmic Transport Signaling Regulation Of Metabolic Process Positive Regulation Of GTPase Activity Regulation Of Signal Transduction Cellular Response To Stimulus Cell Communication Regulation Of Protein Kinase Activity Negative Regulation Of Signaling Negative Regulation Of Exocytosis Protein Targeting
Tagcloud ?			adpkd arl3 autosomal cilia ciliary ciliopathies cleaved couples gga1 golgi gps localize milieu module must pc1 pc2 polycystic polycystin proper proteolytically reach sense tgn traffic trafficking transmembrane tubular whereby
Tagcloud (Difference) ?			adpkd arl3 autosomal cilia ciliary ciliopathies cleaved couples gga1 golgi gps localize milieu module must pc1 pc2 polycystic polycystin proper proteolytically reach sense tgn traffic trafficking transmembrane tubular whereby
Tagcloud (Intersection) ?