RAB5A and SGSM3

Number of citations of the paper that reports this interaction (PubMedID 16923123)
0

Data Source:
BioGRID (two hybrid)

		RAB5A	SGSM3
Description		RAB5A, member RAS oncogene family	small G protein signaling modulator 3
Image			No pdb structure
GO Annotations	Cellular Component	Ruffle Nucleoplasm Cytoplasm Endosome Early Endosome Cytosol Plasma Membrane Synaptic Vesicle Endosome Membrane Endomembrane System Actin Cytoskeleton Membrane Endocytic Vesicle Axon Dendrite Clathrin-coated Endocytic Vesicle Membrane Phagocytic Vesicle Membrane Synaptic Vesicle Membrane Cytoplasmic Vesicle Early Endosome Membrane Early Phagosome Somatodendritic Compartment Melanosome Cell Projection Neuronal Cell Body Terminal Bouton Axon Terminus Membrane Raft Phagocytic Vesicle Extracellular Exosome Cytoplasmic Side Of Early Endosome Membrane	Cytoplasm Cytosol Gap Junction
	Molecular Function	Nucleotide Binding GTPase Activity G Protein Activity Protein Binding GTP Binding Hydrolase Activity Guanyl Nucleotide Binding GDP Binding	GTPase Activator Activity Protein Binding Small GTPase Binding
	Biological Process	Intracellular Protein Transport Endocytosis Phagocytosis Protein Transport Endosomal Transport Receptor Internalization Synaptic Vesicle Recycling Host-mediated Perturbation Of Viral Process Early Endosome To Late Endosome Transport Positive Regulation Of Exocytosis Regulation Of Long-term Neuronal Synaptic Plasticity Plasma Membrane To Endosome Transport Regulation Of Endosome Size Regulation Of Filopodium Assembly Canonical Wnt Signaling Pathway Membrane Fusion Amyloid-beta Clearance By Transcytosis Protein Localization To Early Endosome Regulation Of Synaptic Vesicle Exocytosis Regulation Of Autophagosome Assembly	Endosomal Transport Regulation Of Endocytosis Regulation Of Rab Protein Signal Transduction Rap Protein Signal Transduction Positive Regulation Of GTPase Activity Positive Regulation Of Protein Catabolic Process Plasma Membrane To Endosome Transport Regulation Of Cell Cycle Regulation Of Cilium Assembly
Pathways		Synthesis of PIPs at the plasma membrane TBC/RABGAPs Clathrin-mediated endocytosis RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs Prevention of phagosomal-lysosomal fusion Respiratory syncytial virus (RSV) attachment and entry Factors involved in megakaryocyte development and platelet production
Drugs		L-methionine (S)-S-oxide Guanosine-5'-Triphosphate Guanosine-5'-Diphosphate
Diseases
GWAS		Heel bone mineral density ( 30598549) Iris color (L* coordinate) ( 30895295)	Body mass index ( 26426971) Breast size ( 29855537) Chronotype ( 27494321) Height ( 19570815) Mammographic density (dense area) ( 25342443) Morning vs. evening chronotype ( 27494321) Refractive error ( 32231278) Regular attendance at a pub or social club ( 29970889)
Interacting Genes		37 interacting genes: AGTR1 ALS2CL ANKFY1 APPL1 APPL2 CHML EEA1 GDI2 GRIK4 HTATIP2 ITSN1 NME2 OCRL RAB37 RABAC1 RABEP1 RABEP2 RABGGTB RASA1 RBSN RIN1 RIN2 RIN3 RIT2 RUFY1 SDCBP SGSM3 SNCA STX4 TBC1D15 TBC1D17 TBC1D3C TBC1D3F TRIM14 TSC2 USP6NL WEE2-AS1	10 interacting genes: CHRM3 DSCAM FMO3 GJA1 NF2 RAB39B RAB5A RAB5B RAB5C RPL35
Entrez ID		5868	27352
HPRD ID		01542	15285
Ensembl ID		ENSG00000144566	ENSG00000100359
Uniprot IDs		P20339	B4DVE3 B9A6J5 Q96HU1
PDB IDs		1N6H 1N6I 1N6K 1N6L 1N6N 1N6O 1N6P 1N6R 1R2Q 1TU3 1TU4 3MJH 4Q9U 7BL1
Enriched GO Terms of Interacting Partners?		GTPase Activator Activity Small GTPase Binding Vesicle-mediated Transport Endosome Regulation Of Endocytosis Regulation Of Vesicle-mediated Transport Endocytosis Cytoplasmic Vesicle Regulation Of Cellular Component Organization Cellular Localization Import Into Cell Intracellular Transport Regulation Of Cilium Assembly Endosomal Transport Small GTPase-mediated Signal Transduction Macropinosome Establishment Of Protein Localization Protein Transport Early Endosome Membrane Cytosol Establishment Of Localization In Cell Positive Regulation Of Pinocytosis Regulation Of Transport Early Endosome Regulation Of Organelle Assembly Cytoplasm Positive Regulation Of Macropinocytosis Regulation Of Cell Projection Assembly Endocytic Vesicle Membrane Fusion Positive Regulation Of Endocytosis Rab-protein Geranylgeranyltransferase Complex Phagocytic Vesicle Signal Transduction Intracellular Protein Localization Vesicle Fusion Retrograde Transport, Endosome To Golgi Protein Geranylgeranylation Organelle Membrane Fusion Ruffle Guanyl-nucleotide Exchange Factor Activity Synapse Adiponectin-activated Signaling Pathway Regulation Of Organelle Organization Protein Prenylation Organelle Fusion Cytosolic Transport Plasma Membrane To Endosome Transport Recycling Endosome Cell Projection	Plasma Membrane To Endosome Transport G Protein Activity GDP Binding Endocytic Vesicle Early Endosome GTPase Activity Melanosome GTP Binding Regulation Of Transport Membrane Cell Junction Organization Regulation Of Vesicle-mediated Transport Early Endosome Membrane Endomembrane System Endosomal Transport Plasma Membrane Albendazole Monooxygenase Activity Post-embryonic Retina Morphogenesis In Camera-type Eye Regulation Of Cellular Component Organization Netrin Receptor Binding Trimethylamine Monooxygenase Activity Hypotaurine Monooxygenase Activity Regulation Of Stem Cell Proliferation Endosome Organization Positive Regulation Of Mesodermal Cell Differentiation Gap Junction Channel Activity Involved In Cardiac Conduction Electrical Coupling Schwann Cell Proliferation Ruffle Protein Localization To Early Endosome Intracellular Protein Localization Endocytosis Dendrite N,N-dimethylaniline Monooxygenase Activity Taurine Biosynthetic Process Gap Junction Channel Activity Involved In Cell Communication By Electrical Coupling Cytoplasmic Side Of Early Endosome Membrane Protein Transport Synaptic Vesicle Membrane G Protein-coupled Acetylcholine Receptor Activity Gap Junction Hemi-channel Activity Vesicle-mediated Transport Intracellular Protein Transport Saliva Secretion Positive Regulation Of Axon Extension Involved In Axon Guidance Regulation Of Secretion By Cell Acetylcholine Binding Cell-cell Signaling Adenylate Cyclase-inhibiting G Protein-coupled Acetylcholine Receptor Signaling Pathway Regulation Of Secretion Phospholipase C-activating G Protein-coupled Acetylcholine Receptor Signaling Pathway
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?