CTDSP1 and SNAI1

Number of citations of the paper that reports this interaction (PMID 19004823)
17

Data Source:
HPRD (in vitro, in vivo)

		CTDSP1	SNAI1
Gene Name		CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1	snail family zinc finger 1
Image
Gene Ontology Annotations	Cellular Component	Nucleus Extracellular Vesicular Exosome	Nucleus Cytoplasm
	Molecular Function	Protein Binding CTD Phosphatase Activity Metal Ion Binding	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Negative Regulation Of Transcription Protein Binding Kinase Binding Metal Ion Binding
	Biological Process	Negative Regulation Of Protein Phosphorylation Regulation Of Transcription From RNA Polymerase II Promoter Protein Dephosphorylation Negative Regulation Of Neuron Differentiation Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle	Negative Regulation Of Transcription From RNA Polymerase II Promoter Osteoblast Differentiation Mesoderm Formation Epithelial To Mesenchymal Transition Positive Regulation Of Epithelial To Mesenchymal Transition Negative Regulation Of Vitamin D Biosynthetic Process Cell Migration Positive Regulation Of Cell Migration Hair Follicle Morphogenesis Negative Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Positive Regulation Of Transcription, DNA-templated Palate Development Cartilage Morphogenesis Trophoblast Giant Cell Differentiation Negative Regulation Of Cell Differentiation Involved In Embryonic Placenta Development Left/right Pattern Formation Notch Signaling Involved In Heart Development Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Regulation Of Tight Junction Assembly
Pathways
Drugs
Diseases
GWAS		Inflammatory bowel disease ( 23128233)	Psoriasis ( 20953189)
Protein-Protein Interactions		6 interactors: CDCA3 GTF2F1 LDB1 MBP POLR2A SNAI1	19 interactors: ACTN2 CTDSP1 CTDSP2 CTDSPL FBXL14 FBXL5 GSK3B HIST1H3A HOXD4 KRT31 KRT40 KRTAP10-3 LATS2 MID2 MTUS2 NOTCH1 NOTCH2NL RCOR1 TRIM23
Entrez ID		58190	6615
HPRD ID		05615	05025
Ensembl ID		ENSG00000144579	ENSG00000124216
Uniprot IDs		Q9GZU7	O95863
PDB IDs		1T9Z 1TA0 2GHQ 2GHT 3L0B 3L0C 3L0Y 3PGL	2Y48
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Cell Differentiation Stem Cell Development 7-methylguanosine MRNA Capping Transcription From RNA Polymerase II Promoter 7-methylguanosine RNA Capping Stem Cell Differentiation Positive Regulation Of Viral Transcription Regulation Of DNA-templated Transcription, Elongation Transcription Elongation From RNA Polymerase II Promoter Somatic Stem Cell Maintenance Regulation Of Viral Transcription Positive Regulation Of Viral Process DNA-templated Transcription, Elongation Positive Regulation Of Macromolecule Biosynthetic Process Hair Follicle Development Positive Regulation Of Gene Expression Hair Cycle Process Histone H3-K4 Acetylation Negative Regulation Of Cell Differentiation Involved In Embryonic Placenta Development Transcription-dependent Tethering Of RNA Polymerase II Gene DNA At Nuclear Periphery Regulation Of Cell Differentiation Positive Regulation Of Cellular Biosynthetic Process Hair Cycle Transcription, RNA-templated Positive Regulation Of Hemoglobin Biosynthetic Process Stem Cell Maintenance Regulation Of Viral Process Transcription Initiation From RNA Polymerase II Promoter Defense Response To Nematode Gastrulation Transcription, DNA-templated Negative Regulation Of Vitamin D Biosynthetic Process Regulation Of Hemoglobin Biosynthetic Process DNA-templated Transcription, Initiation RNA Biosynthetic Process Skin Development MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Response To Nematode Positive Regulation Of Cellular Metabolic Process Epidermis Development Notch Signaling Involved In Heart Development Negative Regulation Of Erythrocyte Differentiation Regulation Of Tight Junction Assembly Positive Regulation Of Transcription, DNA-templated RNA Splicing Negative Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Regulation Of Vitamin Metabolic Process Cerebellar Purkinje Cell Differentiation RNA Metabolic Process	Negative Regulation Of Protein Phosphorylation Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Phosphorylation Protein Localization To Microtubule Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Metabolic Process Cellular Protein Modification Process Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G1/S Phase Transition Protein Localization To Cytoskeleton Cellular Protein Metabolic Process Negative Regulation Of Mitotic Cell Cycle Phase Transition Negative Regulation Of Canonical Wnt Signaling Pathway Negative Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Cell Cycle Regulation Of Hematopoietic Progenitor Cell Differentiation Negative Regulation Of Protein Metabolic Process Negative Regulation Of Neuron Differentiation Negative Regulation Of Wnt Signaling Pathway Regulation Of Mitotic Cell Cycle Phase Transition Negative Regulation Of Mitotic Cell Cycle Regulation Of Canonical Wnt Signaling Pathway Regulation Of Cell Cycle Phase Transition Protein Ubiquitination Regulation Of Protein Phosphorylation Wound Healing Positive Regulation Of Stem Cell Differentiation Protein Modification By Small Protein Conjugation Epithelial To Mesenchymal Transition Epidermis Development Venous Endothelial Cell Differentiation Notch Signaling Pathway Involved In Regulation Of Secondary Heart Field Cardioblast Proliferation Protein Metabolic Process Negative Regulation Of Neurogenesis Regulation Of Developmental Growth Response To Wounding Regulation Of Wnt Signaling Pathway Regulation Of Cellular Protein Metabolic Process Regulation Of Phosphorylation Negative Regulation Of Cell Development Negative Regulation Of Type B Pancreatic Cell Development Vasculogenesis Involved In Coronary Vascular Morphogenesis Cardiac Right Atrium Morphogenesis Mitral Valve Formation Superior Temporal Gyrus Development Negative Regulation Of Biosynthetic Process Keratinocyte Differentiation Regulation Of Nitrogen Compound Metabolic Process Cellular Metabolic Process Regulation Of Protein Metabolic Process
Tagcloud ?			aberrations apart aspect ccnd1 clinicopathological copy covered encompassed endometrial erbb1 erbb2 erbb3 erbb4 esr1 frequent infiltration insufficient myometrial pakt1 pgr pik3ca prom1 rad21 rad27 runx1 scgb2a2 snai2 top2a younger
Tagcloud (Difference) ?			aberrations apart aspect ccnd1 clinicopathological copy covered encompassed endometrial erbb1 erbb2 erbb3 erbb4 esr1 frequent infiltration insufficient myometrial pakt1 pgr pik3ca prom1 rad21 rad27 runx1 scgb2a2 snai2 top2a younger
Tagcloud (Intersection) ?