PCBP3 and RBM47

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		PCBP3	RBM47
Description		poly(rC) binding protein 3	RNA binding motif protein 47
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Extracellular Exosome Ribonucleoprotein Complex	Nucleus Cytoplasm Apolipoprotein B MRNA Editing Enzyme Complex
	Molecular Function	Nucleic Acid Binding DNA Binding RNA Binding MRNA Binding Protein Binding C-rich Single-stranded DNA Binding	Nucleic Acid Binding RNA Binding MRNA Binding MRNA 3'-UTR Binding Protein Binding Enzyme Binding Enzyme-substrate Adaptor Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II MRNA Metabolic Process Viral RNA Genome Replication	Regulation Of Alternative MRNA Splicing, Via Spliceosome Hematopoietic Progenitor Cell Differentiation MRNA Processing RNA Splicing Cytidine To Uridine Editing Positive Regulation Of Interleukin-10 Production Low-density Lipoprotein Particle Clearance Positive Regulation Of Type I Interferon-mediated Signaling Pathway 3'-UTR-mediated MRNA Stabilization
Pathways
Drugs
Diseases
GWAS		A body shape index ( 34021172) Ankle injury ( 28957384) Daytime nap ( 33568662) Diffusing capacity of carbon monoxide ( 30694715) Insulin resistance/response ( 21901158) Intraocular pressure ( 29617998) Keratoconus ( 33649486) Low myopia ( 33830181) Macular thickness ( 30535121) Myopia ( 27182965) Refractive error ( 32231278) Spatial processing ( 31596458) Spherical equivalent or myopia (age of diagnosis) ( 29808027) Waist circumference adjusted for body mass index ( 34021172)	Apolipoprotein B levels ( 32203549) Body mass index (change over time) ( 25133637) Carotid intima media thickness x smoking interaction ( 32117412) Diastolic blood pressure ( 27618447) Hypertension ( 27618447) Monocyte count ( 32888494) Mosquito bite size ( 28199695) Systolic blood pressure ( 27618447) Total cholesterol levels ( 30275531) Triglyceride levels in HIV infection ( 33109212)
Interacting Genes		17 interacting genes: APOBEC3C CELF4 DDIT4L HNRNPLL KRT81 MATR3 PTBP1 PTBP2 PUF60 QKI RBM47 RNF4 RUVBL1 SNRPA SREK1 SRSF3 ZC3HAV1	17 interacting genes: C10orf55 C1orf94 CAMK2A CELF5 HIVEP1 HSFY1 MIR16-1 MIR29A MIR29B1 MIRLET7E MIRLET7F1 NUTM2F OTX2 PCBP3 PRR13 RBFOX1 ZNF385C
Entrez ID		54039	54502
HPRD ID		10534	13373
Ensembl ID		ENSG00000183570	ENSG00000163694
Uniprot IDs		P57721	A0AV96 B7Z8Z7
PDB IDs			2DIS
Enriched GO Terms of Interacting Partners?		Nucleic Acid Binding MRNA Processing Regulation Of RNA Splicing RNA Splicing RNA Binding MRNA Metabolic Process Regulation Of MRNA Splicing, Via Spliceosome RNA Processing Regulation Of MRNA Processing MRNA Binding Regulation Of Alternative MRNA Splicing, Via Spliceosome RNA Metabolic Process Regulation Of MRNA Metabolic Process Nucleic Acid Metabolic Process Nucleobase-containing Compound Metabolic Process Pre-mRNA Binding Negative Regulation Of RNA Splicing Negative Regulation Of MRNA Metabolic Process MRNA Splice Site Recognition Macromolecule Metabolic Process Nucleus Ribonucleoprotein Complex Regulation Of Gene Expression MRNA Splicing, Via Spliceosome Protein-RNA Complex Assembly Regulation Of Macromolecule Biosynthetic Process RNA Splicing, Via Transesterification Reactions Cytidine To Uridine Editing Base Conversion Or Substitution Editing Regulation Of Macromolecule Metabolic Process Negative Regulation Of MRNA Splicing, Via Spliceosome Positive Regulation Of Macromolecule Biosynthetic Process Alternative MRNA Splicing, Via Spliceosome Positive Regulation Of MRNA Metabolic Process Positive Regulation Of Biosynthetic Process Regulation Of Primary Metabolic Process RNA Localization Regulation Of RNA Metabolic Process Regulation Of Metabolic Process MiRNA Binding Spliceosomal Complex Positive Regulation Of Gene Expression Positive Regulation Of RNA Splicing Regulation Of Nucleobase-containing Compound Metabolic Process Internal N(7)-methylguanine-containing RNA Reader Activity Regulation Of Retina Development In Camera-type Eye Negative Regulation Of Viral Genome Replication Positive Regulation Of Macromolecule Metabolic Process Poly-pyrimidine Tract Binding Protein-RNA Sequence-specific Adaptor Activity	MRNA Base-pairing Post-transcriptional Repressor Activity RISC Complex MiRNA-mediated Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Post-transcriptional Gene Silencing Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Gene Silencing Negative Regulation Of Mesenchymal Stem Cell Proliferation Regulation Of Mitochondrial Membrane Permeability Involved In Apoptotic Process Negative Regulation Of Amyloid-beta Formation Negative Regulation Of Amyloid Precursor Protein Catabolic Process Negative Regulation Of Circulating Fibrinogen Levels Regulation Of Amyloid-beta Formation MiRNA-mediated Gene Silencing By Inhibition Of Translation Regulation Of Amyloid Precursor Protein Catabolic Process Regulation Of Mitochondrial Membrane Permeability Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle Apoptotic Mitochondrial Changes Regulation Of Membrane Permeability Negative Regulation Of Cell Cycle G1/S Phase Transition Negative Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Regulation Of Amide Metabolic Process Positive Regulation Of Cardiac Muscle Cell Apoptotic Process Extracellular Vesicle Negative Regulation Of Collagen Biosynthetic Process Positive Regulation Of Mitochondrial Membrane Permeability Involved In Apoptotic Process Mitochondrial Outer Membrane Permeabilization Involved In Programmed Cell Death Mitochondrial Membrane Organization Post-transcriptional Regulation Of Gene Expression Regulation Of Gene Expression Regulation Of MRNA Metabolic Process MRNA 3'-UTR Binding Regulation Of Cellular Response To Growth Factor Stimulus Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Stem Cell Proliferation LncRNA Binding Positive Regulation Of Mitochondrial Membrane Permeability Positive Regulation Of Membrane Permeability Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Regulation Of G1/S Transition Of Mitotic Cell Cycle Negative Regulation Of Mitotic Cell Cycle Phase Transition MiRNA-mediated Gene Silencing By MRNA Destabilization Regulation Of Collagen Biosynthetic Process Regulation Of Cell Cycle G1/S Phase Transition Negative Regulation Of Translation Peptidyl-threonine Autophosphorylation C-rich Single-stranded DNA Binding Regulation Of Endothelial Cell Migration Negative Regulation Of Placenta Blood Vessel Development Regulation Of Collagen Metabolic Process Negative Regulation Of Intestinal Epithelial Cell Development
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