CCDC146 and TPM3

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		CCDC146	TPM3
Gene Name		coiled-coil domain containing 146	tropomyosin 3
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component		Stress Fiber Podosome Cytosol Cytoskeleton Muscle Thin Filament Tropomyosin Growth Cone Cortical Cytoskeleton Filamentous Actin Cleavage Furrow Extracellular Vesicular Exosome
	Molecular Function		Molecular_function Actin Binding
	Biological Process		Movement Of Cell Or Subcellular Component Muscle Contraction Muscle Filament Sliding
Pathways			Striated Muscle Contraction Smooth Muscle Contraction
Drugs
Diseases
GWAS		Response to amphetamines ( 22952603)
Protein-Protein Interactions		34 interactors: CCDC136 CCNDBP1 CEP170P1 CEP44 DTNBP1 GMNN GOLGA2 KRT18 KRT19 KRT38 KRT40 MAGEA11 MAGEA6 MED4 MTUS2 NECAB2 NINL NUP62 PDE4DIP PNMA1 PSMC6 RINT1 RNF40 RPGRIP1 SPERT TFIP11 TNR TPM3 TRAF1 TRIM23 TRIM54 TSC22D4 USHBP1 VPS52	41 interactors: ACTA1 ACTB BLOC1S6 C1orf216 CCDC102B CCDC114 CCDC146 CCHCR1 CNN1 FAM9C FBXO5 HDDC3 HSF2 IFIT3 IKBIP KCNE1 KIFC3 KXD1 LCA5L LURAP1 MAD1L1 MAGEA11 NEK2 OIP5 PBX3 S100A2 S100A4 SMAD3 SUMO4 SYCE1 TFPT THAP1 TLK1 TMOD1 TMOD2 TNNT1 TRAP1 TRIM27 TRIP6 VPS52 WASH3P
Entrez ID		57639	7170
HPRD ID		11150	01840
Ensembl ID		ENSG00000135205	ENSG00000143549
Uniprot IDs		Q8IYE0 Q96MS1	B4DQ80 P06753 Q5VU58 Q5VU63 Q8TCG3
PDB IDs
Enriched GO Terms of Interacting Partners?		Cell Cycle Viral Process Mitotic Cell Cycle Regulation Of Signal Transduction Involved In Mitotic G2 DNA Damage Checkpoint Negative Regulation Of Axon Extension Involved In Regeneration Golgi To Plasma Membrane CFTR Protein Transport Spliceosomal Complex Disassembly	Actomyosin Structure Organization Organelle Organization Actin Filament-based Process Regulation Of Organelle Organization Cellular Component Assembly Actin-myosin Filament Sliding Muscle Filament Sliding Actin Cytoskeleton Organization Regulation Of Actin Filament-based Process Cytoskeleton Organization Actin-mediated Cell Contraction Regulation Of Cytoskeleton Organization Actin Filament Organization Actin Filament-based Movement Regulation Of Actin Filament Polymerization Regulation Of Actin Cytoskeleton Organization Pointed-end Actin Filament Capping Regulation Of Chromosome Segregation Regulation Of Actin Polymerization Or Depolymerization Myofibril Assembly Regulation Of Actin Filament Length Cell-cell Junction Organization Regulation Of Mitotic Cell Cycle Muscle Contraction Cell Division Cell Cycle Muscle System Process Organelle Assembly Negative Regulation Of Protein Catabolic Process Regulation Of Mitotic Nuclear Division Cell Development Movement Of Cell Or Subcellular Component Mitotic Nuclear Division Regulation Of Cellular Component Size Regulation Of Protein Complex Assembly Regulation Of Cellular Component Organization Regulation Of Muscle Contraction Positive Regulation Of Transcription Factor Import Into Nucleus Striated Muscle Cell Development Negative Regulation Of Centriole-centriole Cohesion Positive Regulation Of Transforming Growth Factor Beta3 Production Inhibition Of APC-Cdc20 Complex Activity Regulation Of Metaphase Plate Congression Posterior Compartment Specification Anterior Compartment Pattern Formation Negative Regulation Of Cytoskeleton Organization Regulation Of Mitotic Sister Chromatid Separation Arp2/3 Complex-mediated Actin Nucleation Muscle Cell Development Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Tagcloud ?			aacr accelerated advancements ago approved developments discov encodes fda fusions harboring next ntrk1 oncd oncogene oncogenic oncology originally precision rationale rearrangements revisit scientific throughput transforming trk trka trkb trkc
Tagcloud (Difference) ?			aacr accelerated advancements ago approved developments discov encodes fda fusions harboring next ntrk1 oncd oncogene oncogenic oncology originally precision rationale rearrangements revisit scientific throughput transforming trk trka trkb trkc
Tagcloud (Intersection) ?