CCDC146 and PROSER3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CCDC146	PROSER3
Description		coiled-coil domain containing 146	proline and serine rich 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Centrosome Centriole Cytoskeleton Cilium Axoneme Midbody Motile Cilium Ciliary Basal Body Sperm Flagellum Cell Projection Sperm Head-tail Coupling Apparatus	Cytoplasm Centrosome Cytoskeleton
	Molecular Function	Protein Binding Protein-containing Complex Binding	Protein Binding
	Biological Process	Cell Morphogenesis Nucleus Organization Spermatogenesis Spermatid Development Sperm Axoneme Assembly Single Fertilization Cell Population Proliferation Gene Expression Cell Differentiation Flagellated Sperm Motility Cilium Organization Sperm Flagellum Assembly Manchette Assembly
Pathways
Drugs
Diseases
GWAS		Amyloid beta positivity ( 34154648) Appendicular lean mass ( 33097823) Body mass index ( 28892062) Macrovascular complications in type 2 diabetes ( 33430853) Ophthalmic complications in type 2 diabetes ( 33430853) Response to amphetamines ( 22952603)	Age at first sexual intercourse ( 34211149)
Interacting Genes		71 interacting genes: AKAP9 BLOC1S2 CBY2 CCDC136 CCDC197 CCNDBP1 CDR2 CDR2L CENPH CEP170P1 CEP44 CFTR DRC4 DTNBP1 FSD2 GOLGA2 GOLGA6L9 GPRASP2 GRAMD4 HSF2BP INSYN1 KIFC3 KRT16 KRT18 KRT19 KRT24 KRT26 KRT27 KRT31 KRT34 KRT38 KRT40 KRT86 LHX3 MAGEA11 MAGEA6 MCC MED4 MIPOL1 MRFAP1 MTUS2 N4BP3 NAP1L2 NECAB2 NINL NUP62 PDE4DIP PLEKHF2 PNMA1 PPP2R3C PROSER3 PSMC6 RINT1 RNF40 RPGRIP1 SH3BP1 SYCE1L TEPSIN TFIP11 THOC7 TNR TPM3 TRAF1 TRIM23 TRIM54 TRIML2 TSC22D4 TXLNA USHBP1 VPS28 VPS52	8 interacting genes: CCDC146 CCDC57 CCHCR1 CDC23 IQCC NME7 SGF29 ZNF396
Entrez ID		57639	148137
HPRD ID		11150	14079
Ensembl ID		ENSG00000135205	ENSG00000167595
Uniprot IDs		Q8IYE0 Q96MS1	A0A2R8Y8D9 A0A8Q3WKY3 A0A8Q3WKY6 A0A8Q3WKY7 Q2NL68
PDB IDs
Enriched GO Terms of Interacting Partners?		Structural Constituent Of Skin Epidermis Intermediate Filament Cytoskeleton Organization Keratin Filament Intermediate Filament-based Process Intermediate Filament Organization Intermediate Filament Cytoskeleton Organization Cytoskeleton Structural Molecule Activity Organelle Organization Supramolecular Fiber Organization Epithelial Cell Differentiation Microtubule-based Process Protein Binding Morphogenesis Of An Epithelium Centrosome Cycle Tissue Morphogenesis Microtubule Nucleation Centrosome Microtubule Organizing Center Organization Microtubule Cytoskeleton Organization Microtubule Binding Vesicle Transport Along Microtubule	Centriole Cilium Organization Cilium Assembly Cell Projection Assembly Plasma Membrane Bounded Cell Projection Assembly Positive Regulation Of Mitotic Cell Cycle Sperm Flagellum Flagellated Sperm Motility Cilium Movement Involved In Cell Motility Sperm Motility Cilium-dependent Cell Motility Methylation-dependent Protein Binding
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