RPS6KB1 and AKT1

  • Number of citations of the paper that reports this interaction (PMID 11438723)
  • 10
  • Data Source:
  • HPRD (in vitro)

RPS6KB1

AKT1

Gene Name ribosomal protein S6 kinase, 70kDa, polypeptide 1 v-akt murine thymoma viral oncogene homolog 1
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 54 interactors: ACTA1 AKT1 APP BTK CDC42 CDK1 CLEC3B COASY CSNK2A1 CSNK2B DPPA4 EEF2K EIF4B EIF4EBP1 EP300 GDI2P1 HTT IRS1 KAT2B KIR3DL1 LYN MAPK1 MAPK3 MAPK8 MAPK9 MAPT MLST8 MTOR MXD1 NCBP1 NEDD4 NEK6 NR1I2 PDK1 PDPK1 PIK3CA PIN1 POLDIP3 PPP1R9A PPP1R9B PPP2CA RAC1 RBX1 RHEB RICTOR RPS6 RPTOR SRC STK11 SYK TERT TRAF4 URI1 XPO1 191 interactors: ACAP1 AHNAK AKT1S1 AKT2 AKTIP ALYREF APLP2 APOH APP APPL1 AR ARFIP2 ARHGAP29 ARHGAP32 ATXN1 BAD BCL10 BCL2L1 BCL2L11 BPGM BRAF BRCA1 CAMKK1 CARHSP1 CASP3 CASP9 CCDC88A CDKN1A CDKN1B CDKN1C CHEK1 CHN2 CHUK CLIP3 CLK2 CREB1 CREBBP CSNK2A1 CTNNB1 CYLD DAB2IP DCTN1 DLC1 DNAJB1 DNMT1 EEF1G EIF4EBP1 EP300 ESR1 ESR2 EZH2 FANCA FOXO1 FOXO3 FOXO4 GAB2 GATA1 GATA2 GRB10 GSK3A GSK3B HIST2H2BE HMOX1 HSP90AA1 HSP90AB1 HSPB1 HTT IKBKB ILK IMPDH2 IRAK1 IRS1 ITGB3 ITPR1 ITPR3 JADE1 KAT2B KAT6A KRT10 KTN1 LRRK2 MAP2K4 MAP3K11 MAP3K5 MAP3K8 MAPK14 MAPK8IP1 MAPKAPK2 MAPT MDM2 MDM4 METTL1 MS4A2 MST1R MTCP1 MTOR MUL1 MXD1 NCOA4 NCOR2 NF2 NOS3 NOTCH1 NR4A1 PAK1 PAK6 PDE3B PDK2 PDPK1 PEA15 PFKFB1 PFKFB2 PHB2 PI4K2B PIAS1 PIAS2 PIK3R1 PKN2 PLCG1 PLEKHO1 PLXNA1 PPARGC1B PPL PPM1A PPP1CA PPP2CA PPP2R1A PPP2R4 PRG2 PRKCQ PRKCZ PRKDC PTEN PTPN1 RAB3D RAC1 RAF1 RARA RGCC RHEBL1 RICTOR RNF11 RNF115 RPS6KB1 RQCD1 S1PR1 SETDB1 SH2B2 SH3RF1 SIRT1 SIRT6 SKI SKP2 SMAD2 SMAD3 SMAD4 SMAD7 SMARCB1 SMARCC1 SNCA SORBS2 SORBS3 SRC STAT1 STK3 STK4 TBC1D4 TCL1A TCL1B TCL6 TERF2IP TERT THEM4 TNFSF11 TOPBP1 TRIB3 TSC1 TSC2 TTC3 USP4 UXS1 VEGFA VIM WNK1 WNK4 XIAP YAP1 YBX1 YWHAZ ZFP36L1 ZHX1
Entrez ID 6198 207
HPRD ID 10202 01261
Ensembl ID ENSG00000108443 ENSG00000142208
Uniprot IDs B2R779 B4DLT4 B4DTG1 F6UYM1 P23443 Q7Z721 B0LPE5 B3KVH4 P31749
PDB IDs 3A60 3A61 3A62 4L3J 4L3L 4L42 4L43 4L44 4L45 4L46 1H10 1UNP 1UNQ 1UNR 2UVM 2UZR 2UZS 3CQU 3CQW 3MV5 3MVH 3O96 3OCB 3OW4 3QKK 3QKL 3QKM 4EJN 4EKK 4EKL 4GV1
Enriched GO Terms of Interacting Partners?
Tagcloud ?
70kda  ablation  amp  ampk  aortas  apoe  apolipoprotein  arg2  arginase  atherogenesis  atherosclerosis  atherosclerotic  autophagy  crosstalk  h160f  impairs  interested  mtorc1  mtorc2  nonsenescent  polypeptide  prkaa  replicative  rictor  s6k1  senescent  ureahydrolase  wk 
advance  catenin  contributes  decreasing  deregulation  doi  dramatically  foxo1  glioma  gliomas  implicate  inducing  insights  introduction  invasion  january  micrornas  mir  mirnas  onc  oncogene  online  phosphorylated  publication  silencing  suppressed  tissues  tumorigenesis  unfavorable 
Tagcloud (Difference) ?
70kda  ablation  amp  ampk  aortas  apoe  apolipoprotein  arg2  arginase  atherogenesis  atherosclerosis  atherosclerotic  autophagy  crosstalk  h160f  impairs  interested  mtorc1  mtorc2  nonsenescent  polypeptide  prkaa  replicative  rictor  s6k1  senescent  ureahydrolase  wk 
advance  catenin  contributes  decreasing  deregulation  doi  dramatically  foxo1  glioma  gliomas  implicate  inducing  insights  introduction  invasion  january  micrornas  mir  mirnas  onc  oncogene  online  phosphorylated  publication  silencing  suppressed  tissues  tumorigenesis  unfavorable 
Tagcloud (Intersection) ?