RPS6KB1 and IRS1

  • Number of citations of the paper that reports this interaction (PMID 23045529)
  • 1
  • Data Source:
  • BioGRID (enzymatic study)

RPS6KB1

IRS1

Gene Name ribosomal protein S6 kinase, 70kDa, polypeptide 1 insulin receptor substrate 1
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 54 interactors: ACTA1 AKT1 APP BTK CDC42 CDK1 CLEC3B COASY CSNK2A1 CSNK2B DPPA4 EEF2K EIF4B EIF4EBP1 EP300 GDI2P1 HTT IRS1 KAT2B KIR3DL1 LYN MAPK1 MAPK3 MAPK8 MAPK9 MAPT MLST8 MTOR MXD1 NCBP1 NEDD4 NEK6 NR1I2 PDK1 PDPK1 PIK3CA PIN1 POLDIP3 PPP1R9A PPP1R9B PPP2CA RAC1 RBX1 RHEB RICTOR RPS6 RPTOR SRC STK11 SYK TERT TRAF4 URI1 XPO1 73 interactors: AKT1 ALK AP3S1 APP ATP2A1 ATP2A2 ATP2A3 BCL2L1 BCR CAV1 CDH1 CHUK CRK CSNK2A1 CSNK2B EGFR ERBB2 FBXO25 FBXW8 FER FES FYN GHR GRB10 GRB14 GRB2 IGF1R IKBKB IL4R INSR JAK1 JAK2 JAK3 MAPK1 MAPK8 MAPK9 MTOR NCK2 NEDD4 NPM1 NTRK1 PDPK1 PHIP PIK3R1 PIK3R2 PIK3R3 PLCG2 PRKCD PRKCG PRKCQ PRKCZ PTK2 PTPN1 PTPN11 PTPRC PTPRF PTPRU RAD51 ROCK1 RPS6KB1 RPTOR SH2B1 SHC1 SIK2 SOCS1 SOCS3 TUB TYK2 UBTF YWHAB YWHAE YWHAG YWHAZ
Entrez ID 6198 3667
HPRD ID 10202 00943
Ensembl ID ENSG00000108443 ENSG00000169047
Uniprot IDs B2R779 B4DLT4 B4DTG1 F6UYM1 P23443 Q7Z721 P35568
PDB IDs 3A60 3A61 3A62 4L3J 4L3L 4L42 4L43 4L44 4L45 4L46 1IRS 1K3A 1QQG 2Z8C
Enriched GO Terms of Interacting Partners?
Tagcloud ?
70kda  ablation  amp  ampk  aortas  apoe  apolipoprotein  arg2  arginase  atherogenesis  atherosclerosis  atherosclerotic  autophagy  crosstalk  h160f  impairs  interested  mtorc1  mtorc2  nonsenescent  polypeptide  prkaa  replicative  rictor  s6k1  senescent  ureahydrolase  wk 
action  adipocytes  biochem  biophys  coimmunoprecipitation  coincided  commun  docking  evidenced  extent  gh  initiating  insulin  involvement  kda  kinase  phosphatidylinositol  phosphorylated  pi  postreceptor  res  ridderstrale  seems  substrate  thereby  tornqvist  tyrosine  wortmannin 
Tagcloud (Difference) ?
70kda  ablation  amp  ampk  aortas  apoe  apolipoprotein  arg2  arginase  atherogenesis  atherosclerosis  atherosclerotic  autophagy  crosstalk  h160f  impairs  interested  mtorc1  mtorc2  nonsenescent  polypeptide  prkaa  replicative  rictor  s6k1  senescent  ureahydrolase  wk 
action  adipocytes  biochem  biophys  coimmunoprecipitation  coincided  commun  docking  evidenced  extent  gh  initiating  insulin  involvement  kda  kinase  phosphatidylinositol  phosphorylated  pi  postreceptor  res  ridderstrale  seems  substrate  thereby  tornqvist  tyrosine  wortmannin 
Tagcloud (Intersection) ?