SCYL3 and GABARAPL1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SCYL3	GABARAPL1
Description		SCY1 like pseudokinase 3	GABA type A receptor associated protein like 1
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Cytoplasm Endoplasmic Reticulum Golgi Apparatus Cytosol Lamellipodium Cell Projection	Autophagosome Membrane Cytoplasm Mitochondrion Autophagosome Endoplasmic Reticulum Golgi Apparatus Cytosol Cytoskeleton Microtubule Plasma Membrane Cilium Membrane Cytoplasmic Vesicle Membrane Cytoplasmic Vesicle Ciliary Basal Body
	Molecular Function	Protein Binding ATP Binding Kinase Activity Identical Protein Binding	Protein Binding Phospholipid Binding Phosphatidylethanolamine Binding Tat Protein Binding Ubiquitin Protein Ligase Binding Beta-tubulin Binding GABA Receptor Binding
	Biological Process	Inflammatory Response Intracellular Protein Localization Cell Migration Spinal Cord Motor Neuron Differentiation Neuron Development	Autophagosome Assembly Mitophagy Autophagy Cellular Response To Nitrogen Starvation Glycophagy Autophagosome Maturation
Pathways			Macroautophagy
Drugs
Diseases
GWAS		Acute anterior uveitis in ankylosing spondylitis ( 32492107)
Interacting Genes		7 interacting genes: EZR GABARAPL1 GABARAPL2 LHX8 SHANK3 TCAF1 TXN2	87 interacting genes: AHNAK2 AMBRA1 ANK2 APPL1 ARFGAP1 ATG13 ATG4A ATG4B ATG4D AZI2 BICC1 BNIP3L BRD9 BSCL2 BSDC1 CALCOCO1 CALCOCO2 CARS2 CCT2 CDC37 CREB3L2 CUL3 DISC1 DVL2 DYNLL1 ERBB2 ERBB3 FUNDC1 G3BP1 KBTBD7 KRTAP10-3 KRTAP10-7 KRTAP10-9 KXD1 MAP4K2 MAPK15 MEFV MLX MYBPC1 NCOR1 NEDD4 NFIA NUFIP2 OPRK1 OPTN OSBPL3 PBXIP1 PSMB4 PTPRR RABGAP1 RABGAP1L RB1CC1 RCN2 RESF1 RETREG3 SCYL3 SEC62 SNCA SQSTM1 SRPK1 SRPK2 STK3 STRN3 TAX1BP1 TBC1D1 TBC1D10A TBC1D10B TBC1D16 TBC1D17 TBC1D2 TBC1D25 TBC1D2B TBC1D5 TBC1D7 TBC1D9 TBC1D9B THAP7 TMEM131 TNIP1 TP53INP1 TRIM21 TRIM25 TRIM32 UMAD1 VDR WDFY3 ZBTB22
Entrez ID		57147	23710
HPRD ID		07459	07601
Ensembl ID		ENSG00000000457	ENSG00000139112
Uniprot IDs		Q8IZE3	Q9H0R8
PDB IDs			2L8J 2R2Q 5DPT 5LXH 5LXI 6HOI 6HOL 6YOO 7AA7 7AA9 7JHX 8X8A
Enriched GO Terms of Interacting Partners?		Cellular Response To Nitrogen Starvation Phosphatidylethanolamine Binding GABA Receptor Binding Organelle Assembly Beta-tubulin Binding Autophagosome Maturation Mitophagy Autophagosome Membrane Autophagy Of Mitochondrion ATPase Binding Autophagosome Terminal Web Assembly Positive Regulation Of Anion Channel Activity Autophagosome Organization Autophagosome Assembly Guanylate Kinase-associated Protein Clustering Protein Localization To Cell Cortex Intestinal D-glucose Absorption Positive Regulation Of Monoatomic Anion Transport Phospholipid Binding Positive Regulation Of Synapse Structural Plasticity Striatal Medium Spiny Neuron Differentiation Protein-containing Complex Disassembly Intestinal Hexose Absorption Synaptic Receptor Adaptor Activity Membrane To Membrane Docking Regulation Of Microvillus Length Macroautophagy Negative Regulation Of Cell Volume AMPA Glutamate Receptor Clustering NMDA Glutamate Receptor Clustering Vacuole Organization Cellular Response To Starvation Microvillus Assembly Postsynaptic Density Assembly Regulation Of Synapse Structural Plasticity Microvillus Organization Regulation Of Cellular Component Size Positive Regulation Of Early Endosome To Late Endosome Transport Positive Regulation Of Protein Localization To Early Endosome Establishment Of Centrosome Localization Microtubule Binding Regulation Of Cell Projection Size Negative Regulation Of P38MAPK Cascade Cortical Microtubule Organization Astral Microtubule Organization Response To Starvation Cellular Response To Nutrient Levels Tat Protein Binding Vocal Learning	Autophagosome Regulation Of Cilium Assembly Autophagy Macroautophagy GTPase Activator Activity Regulation Of Organelle Assembly Cytosol Regulation Of Autophagy Positive Regulation Of Autophagy Autophagy Of Mitochondrion Regulation Of Cell Projection Assembly Mitophagy Autophagosome Assembly Autophagosome Organization Aggrephagy Cytoplasmic Vesicle Piecemeal Microautophagy Of The Nucleus Cytoplasm Regulation Of Cell Projection Organization Microautophagy Nucleophagy Positive Regulation Of Catabolic Process Regulation Of Plasma Membrane Bounded Cell Projection Organization Vacuole Organization Regulation Of Organelle Organization Positive Regulation Of Metabolic Process Protein-phosphatidylethanolamide Deconjugating Activity Catabolic Process Protein Delipidation Response To Mitochondrial Depolarisation Organelle Assembly Regulation Of Macroautophagy Atg1/ULK1 Kinase Complex Regulation Of Cellular Component Organization Positive Regulation Of Macroautophagy Regulation Of Intracellular Signal Transduction Protein Polyubiquitination Negative Regulation Of Cell Communication Negative Regulation Of Signaling Regulation Of Signal Transduction Phagophore Assembly Site Negative Regulation Of Signal Transduction ERBB3:ERBB2 Complex Protein Localization To Phagocytic Vesicle Regulation Of Toll-like Receptor 4 Signaling Pathway Regulation Of Metabolic Process Response To Stress Regulation Of Signaling Regulation Of Cell Communication Negative Regulation Of Viral Process
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