SCYL3 and TCAF1

Number of citations: 50 (PubMedID 32296183)
Data Source: BioGRID (two hybrid)

		SCYL3	TCAF1
Name		SCY1 like pseudokinase 3	TRPM8 channel associated factor 1
Structure		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Cytoplasm Endoplasmic Reticulum Golgi Apparatus Cytosol Lamellipodium Cell Projection	Plasma Membrane Membrane
	Molecular Function	Protein Binding ATP Binding Kinase Activity Identical Protein Binding	Protein Binding Transmembrane Transporter Binding
	Biological Process	Inflammatory Response Intracellular Protein Localization Cell Migration Spinal Cord Motor Neuron Differentiation Neuron Development	Negative Regulation Of Cell Migration Positive Regulation Of Protein Targeting To Membrane Positive Regulation Of Anion Channel Activity
GWAS		Acute anterior uveitis in ankylosing spondylitis ( 32492107 )	No GWAS studies recorded
Interacting Genes		7 interacting genes: EZR GABARAPL1 GABARAPL2 LHX8 SHANK3 TCAF1 TXN2	36 interacting genes: BIRC2 CAMK2A CEP70 CNKSR1 COIL CYSRT1 DISC1 EFEMP2 IKZF3 IKZF4 KRTAP1-3 KRTAP10-8 KRTAP13-2 KRTAP6-3 MAD1L1 MID2 NBPF19 NFYA PRDM14 PRDM6 RBAK SCYL3 SF3B4 SPRY2 TAX1BP1 TCF3 TFIP11 TRAF2 TRIM42 TRIM54 TRIP6 UBC ZNF143 ZNF24 ZNF263 ZNF592
Entrez ID		57147	9747
HPRD ID		07459	13813
Ensembl ID		ENSG00000000457	ENSG00000198420
Uniprot IDs		Q8IZE3	B4DST7 Q9Y4C2
PDB IDs		Not available	Not available
GO Terms Enriched among Interactors		Cellular Response To Nitrogen Starvation Phosphatidylethanolamine Binding GABA Receptor Binding Organelle Assembly Beta-tubulin Binding Autophagosome Maturation Mitophagy Autophagosome Membrane Autophagy Of Mitochondrion ATPase Binding Autophagosome Terminal Web Assembly Positive Regulation Of Anion Channel Activity Autophagosome Organization Autophagosome Assembly Guanylate Kinase-associated Protein Clustering Protein Localization To Cell Cortex Intestinal D-glucose Absorption Positive Regulation Of Monoatomic Anion Transport Phospholipid Binding Positive Regulation Of Synapse Structural Plasticity Striatal Medium Spiny Neuron Differentiation Protein-containing Complex Disassembly Intestinal Hexose Absorption Synaptic Receptor Adaptor Activity Membrane To Membrane Docking Regulation Of Microvillus Length Macroautophagy Negative Regulation Of Cell Volume AMPA Glutamate Receptor Clustering NMDA Glutamate Receptor Clustering Vacuole Organization Cellular Response To Starvation Microvillus Assembly Postsynaptic Density Assembly Regulation Of Synapse Structural Plasticity Microvillus Organization Regulation Of Cellular Component Size Positive Regulation Of Early Endosome To Late Endosome Transport Positive Regulation Of Protein Localization To Early Endosome Establishment Of Centrosome Localization Microtubule Binding Regulation Of Cell Projection Size Negative Regulation Of P38MAPK Cascade Cortical Microtubule Organization Astral Microtubule Organization Response To Starvation Cellular Response To Nutrient Levels Tat Protein Binding Vocal Learning	Zinc Ion Binding Identical Protein Binding