TUBGCP4 and FBF1

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
BioGRID (two hybrid, two hybrid)
HPRD (two hybrid)

		TUBGCP4	FBF1
Gene Name		tubulin, gamma complex associated protein 4	Fas (TNFRSF6) binding factor 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Spindle Pole Centrosome Cytosol Microtubule Gamma-tubulin Ring Complex Microtubule Cytoskeleton Membrane Recycling Endosome	Spindle Pole Centrosome Centriole Cytosol Apical Junction Complex Keratin Filament Ciliary Transition Fiber
	Molecular Function	Structural Constituent Of Cytoskeleton	Protein Binding
	Biological Process	G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Protein Complex Assembly Microtubule Nucleation	Organelle Organization Cilium Assembly Apical Junction Assembly Establishment Of Epithelial Cell Polarity
Pathways		G2/M Transition Centrosome maturation Mitotic G2-G2/M phases Recruitment of NuMA to mitotic centrosomes Cell Cycle, Mitotic Recruitment of mitotic centrosome proteins and complexes	Organelle biogenesis and maintenance Assembly of the primary cilium Anchoring of the basal body to the plasma membrane
Drugs
Diseases
GWAS
Protein-Protein Interactions		26 interactors: ADAMTSL4 AP2B1 CCDC85B CHIC2 DGCR6 EFHC2 FBF1 GFAP GLYCTK GOLGA2 KCTD17 KRT15 KRT18 LZTR1 MAD1L1 NUDT3 OBFC1 PAK7 RNF146 RPRD1B SDSL SPERT TRIM27 TUBG1 USHBP1 VIM	48 interactors: ABI3 ACCS AES APP BLZF1 CALCOCO2 CCDC102B CCDC67 CCDC85B CEP55 CEP63 CINP DGCR6 FAM208B FAS GATA1 GCC1 GOLGA2 HIF1AN IFT20 IKZF3 KRT13 KRT31 KRT40 LZTS2 MEOX2 MID2 MIPOL1 PNMA1 RBPMS RHOXF2 SSX2IP SUMO1 TADA2A TCEA2 TEX11 TMCC2 TRAF1 TRAF2 TRIM23 TRIM27 TRIM29 TRIM54 TSGA10 TTC32 TUBGCP4 USHBP1 VPS37B
Entrez ID		27229	85302
HPRD ID		10616	10948
Ensembl ID		ENSG00000137822	ENSG00000188878
Uniprot IDs		Q9UGJ1	J3KPL7 Q8TES7
PDB IDs		3RIP
Enriched GO Terms of Interacting Partners?		Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Bergmann Glial Cell Differentiation Intermediate Filament Organization Astrocyte Development Cytoskeleton Organization Golgi To Plasma Membrane Transport Astrocyte Differentiation Diphosphoinositol Polyphosphate Catabolic Process Regulation Of Metaphase Plate Congression Golgi To Plasma Membrane CFTR Protein Transport Diadenosine Polyphosphate Catabolic Process Positive Regulation Of Schwann Cell Proliferation Organelle Organization Negative Regulation Of Interleukin-2 Secretion	Regulation Of Binding Cellular Component Assembly Negative Regulation Of Binding Microtubule-based Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Protein Binding Regulation Of RNA Metabolic Process Neuron Death Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Mitotic Cell Cycle Centriole Assembly Negative Regulation Of Viral Release From Host Cell Cell Cycle Regulation Of Extrinsic Apoptotic Signaling Pathway Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Regulation Of Signal Transduction Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of Gene Expression Negative Regulation Of RNA Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Negative Regulation Of Viral Transcription Regulation Of Viral Release From Host Cell Regulation Of Transcription From RNA Polymerase II Promoter Organelle Assembly Transcription, DNA-templated Regulation Of Signaling Positive Regulation Of NF-kappaB Transcription Factor Activity Immune Response Negative Regulation Of Gene Expression Organelle Organization Protein Complex Assembly Protein K63-linked Ubiquitination Negative Regulation Of Biosynthetic Process Microtubule-based Transport RNA Biosynthetic Process Positive Regulation Of Proteolysis Protein Trimerization Intraciliary Transport Cytoskeleton-dependent Intracellular Transport Regulation Of Protein Localization Peptidyl-histidine Hydroxylation Peptidyl-asparagine Hydroxylation Opsin Transport Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Peptidase Activity Innate Immune Response Negative Regulation Of Nucleic Acid-templated Transcription Protein Localization To Golgi Apparatus
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