TUBGCP4 and OBFC1

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		TUBGCP4	OBFC1
Gene Name		tubulin, gamma complex associated protein 4	oligonucleotide/oligosaccharide-binding fold containing 1
Image
Gene Ontology Annotations	Cellular Component	Spindle Pole Centrosome Cytosol Microtubule Gamma-tubulin Ring Complex Microtubule Cytoskeleton Membrane Recycling Endosome	Nuclear Chromosome, Telomeric Region Nucleus Nucleoplasm Nucleolus Intracellular Membrane-bounded Organelle Intermediate Filament Cytoskeleton Stn1-Ten1 Complex
	Molecular Function	Structural Constituent Of Cytoskeleton	Single-stranded DNA Binding Protein Binding Single-stranded Telomeric DNA Binding
	Biological Process	G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Protein Complex Assembly Microtubule Nucleation	Telomere Maintenance Telomere Maintenance Via Telomere Lengthening Positive Regulation Of DNA Replication
Pathways		G2/M Transition Centrosome maturation Mitotic G2-G2/M phases Recruitment of NuMA to mitotic centrosomes Cell Cycle, Mitotic Recruitment of mitotic centrosome proteins and complexes
Drugs
Diseases
GWAS			Endothelial function traits ( 17903301) Interstitial lung disease ( 23583980) Telomere length ( 23535734 20421499 23001564) Uterine fibroids ( 21460842)
Protein-Protein Interactions		26 interactors: ADAMTSL4 AP2B1 CCDC85B CHIC2 DGCR6 EFHC2 FBF1 GFAP GLYCTK GOLGA2 KCTD17 KRT15 KRT18 LZTR1 MAD1L1 NUDT3 OBFC1 PAK7 RNF146 RPRD1B SDSL SPERT TRIM27 TUBG1 USHBP1 VIM	6 interactors: APP LDLRAP1 MVP TPP1 TUBGCP4 ZDHHC17
Entrez ID		27229	79991
HPRD ID		10616	14872
Ensembl ID		ENSG00000137822
Uniprot IDs		Q9UGJ1	Q9H668
PDB IDs		3RIP	4JOI 4JQF
Enriched GO Terms of Interacting Partners?		Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Bergmann Glial Cell Differentiation Intermediate Filament Organization Astrocyte Development Cytoskeleton Organization Golgi To Plasma Membrane Transport Astrocyte Differentiation Diphosphoinositol Polyphosphate Catabolic Process Regulation Of Metaphase Plate Congression Golgi To Plasma Membrane CFTR Protein Transport Diadenosine Polyphosphate Catabolic Process Positive Regulation Of Schwann Cell Proliferation Organelle Organization Negative Regulation Of Interleukin-2 Secretion	Regulation Of Binding Regulation Of Protein Tyrosine Kinase Activity Neuromuscular Process Controlling Balance Negative Regulation Of Establishment Of Blood-brain Barrier Positive Regulation Of Single-stranded Telomeric DNA Binding Cholesterol Metabolic Process Sterol Metabolic Process Neuromuscular Process Regulation Of Establishment Of Blood-brain Barrier Synaptic Growth At Neuromuscular Junction Regulation Of Protein Kinase Activity Regulation Of Protein Binding Regulation Of Kinase Activity Collateral Sprouting In Absence Of Injury Receptor-mediated Endocytosis Of Low-density Lipoprotein Particle Involved In Cholesterol Transport Intermembrane Transport Chemical Homeostasis Vitamin E Metabolic Process Regulation Of Peptidyl-tyrosine Phosphorylation Collateral Sprouting Axon Midline Choice Point Recognition Protection From Non-homologous End Joining At Telomere Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Telomere Capping Protein Localization To Chromosome, Telomeric Region Negative Regulation Of Telomere Maintenance Via Telomerase Axon Choice Point Recognition Positive Regulation Of Telomerase Activity Telomere Assembly Regulation Of Protein Phosphorylation Steroid Metabolic Process Transport Neuron Remodeling Positive Regulation Of Cholesterol Metabolic Process Intracellular Cholesterol Transport Intracellular Sterol Transport Negative Regulation Of Telomere Maintenance Regulation Of Telomere Maintenance Via Telomerase Lipid Metabolic Process Negative Regulation Of Cell Development Regulation Of Phosphorylation Negative Regulation Of Protein Autophosphorylation Alcohol Metabolic Process Peptide Catabolic Process Protein Metabolic Process Homeostatic Process Regulation Of Signaling Protein Transport Regulation Of Telomerase Activity Regulation Of Cellular Amino Acid Metabolic Process
Tagcloud ?			aa ac ages biology cardiovascular caucasian cc cvd disequilibrium enrolled estimate etiologic genotyped hr insight intervals leukocyte linkage ltl minor polymorphisms rs3772190 rs4387287 rs9419958 similarly snps telomere terc trend
Tagcloud (Difference) ?			aa ac ages biology cardiovascular caucasian cc cvd disequilibrium enrolled estimate etiologic genotyped hr insight intervals leukocyte linkage ltl minor polymorphisms rs3772190 rs4387287 rs9419958 similarly snps telomere terc trend
Tagcloud (Intersection) ?